Výsledky vyhľadávania - "Dar, Abid Hamid"
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The modulation of PI3K/Akt pathway by 3β hydroxylup‐12‐en‐28‐oic acid isolated from Thymus linearis induces cell death in HCT‐116 cells
ISSN: 1747-0277, 1747-0285, 1747-0285Vydavateľské údaje: England 01.01.2022Vydané v Chemical biology & drug design (01.01.2022)“…The presence of intricate carbon skeletons in natural compounds enhances their bioactivity spectrum with unique modes of action at several targets in various…”
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Emerging role of sphingolipids and extracellular vesicles in development and therapeutics of cardiovascular diseases
ISSN: 2352-9067, 2352-9067Vydavateľské údaje: Ireland Elsevier B.V 01.08.2024Vydané v International journal of cardiology. Heart & vasculature (01.08.2024)“…•Highlight the role of Sphingolipid pathway in CVDs and biogenesis and secretion ofsmall extracellular vesicles (sEVs)/ exosomes.•The manuscript highlights the…”
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Bioactive potential of Lagotis cashmeriana: a study on morphology, phytochemicals, and antioxidant activity
ISSN: 1478-6419, 1478-6427, 1478-6427Vydavateľské údaje: England Taylor & Francis 02.09.2025Vydané v Natural product research (02.09.2025)“…The present study aimed to investigate the morphological features, phytochemicals, phenolic content, and antioxidant activity in different parts of Lagotis…”
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Role of human organic cation transporter-1 (OCT-1/SLC22A1) in modulating the response to metformin in patients with type 2 diabetes
ISSN: 1472-6823, 1472-6823Vydavateľské údaje: London BioMed Central 26.05.2022Vydané v BMC endocrine disorders (26.05.2022)“…Background Organic cation transporter 1 primarily governs the action of metformin in the liver. There are considerable inter-individual variations in metformin…”
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Extracellular vesicles: A new paradigm in understanding, diagnosing and treating neurodegenerative disease
ISSN: 1663-4365, 1663-4365Vydavateľské údaje: Frontiers Media S.A 03.11.2022Vydané v Frontiers in aging neuroscience (03.11.2022)“…Neurodegenerative disorders (NDs) are becoming one of the leading causes of disability and death across the globe due to lack of timely preventions and…”
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Tumor microenvironment promotes breast cancer chemoresistance
ISSN: 0344-5704, 1432-0843, 1432-0843Vydavateľské údaje: Berlin/Heidelberg Springer Berlin Heidelberg 01.02.2021Vydané v Cancer chemotherapy and pharmacology (01.02.2021)“…Breast cancer is presently the most predominant tumor type and the second leading cause of tumor-related deaths among women. Although advancements in diagnosis…”
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Chlorpyrifos and dimethoate exposure impairs female fertility by deregulating WNT signaling pathway & uterine receptivity
ISSN: 0890-6238, 1873-1708, 1873-1708Vydavateľské údaje: United States Elsevier Inc 01.12.2024Vydané v Reproductive toxicology (Elmsford, N.Y.) (01.12.2024)“…The study assessed histological, biochemical, oxidative stress, and molecular parameters to evaluate the consequences of Chlorpyrifos and Dimethoate exposure…”
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Pesticide-induced epigenetic suppression of WNT signaling and NF-κB-driven inflammation impairs ovarian function in rats
ISSN: 0278-6915, 1873-6351, 1873-6351Vydavateľské údaje: England Elsevier Ltd 01.11.2025Vydané v Food and chemical toxicology (01.11.2025)“…The study examined the impact of chlorpyrifos, dimethoate, and their co-exposure on ovarian structure and function in female Wistar rats. The study involved 24…”
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Synthesis and Biological Evaluation of Novel Uracil Derivatives as Thymidylate Synthase Inhibitors
ISSN: 0273-2289, 1559-0291, 1559-0291Vydavateľské údaje: New York Springer US 01.10.2023Vydané v Applied biochemistry and biotechnology (01.10.2023)“…Cell division is driven by nucleic acid metabolism, and thymidylate synthase (TYMS) catalyzes a rate-limiting step in nucleotide synthesis. As a result,…”
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Genotoxicity and immunotoxic effects of 1,2-dichloroethane in Wistar rats
ISSN: 1059-0501, 1532-4095, 1532-4095Vydavateľské údaje: United States Taylor & Francis 02.07.2016Vydané v Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews (02.07.2016)“…Dichloroethane is widely used as a solvent, degreasing agent and in a variety of commercial products, and is known for being a ubiquitous contaminant in the…”
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Biochemical and Molecular Mechanisms of Intestinal Folate Transport Regulation in Chronic Ethanol Fed Rats
ISBN: 9798286484591Vydavateľské údaje: ProQuest Dissertations & Theses 01.01.2006“…Folate is an essential vitamin for normal cellular proliferation and tissue regeneration. It can't be synthesized by mammals; rather, it is obtained from…”
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Dissertation

