Search Results - "Curcumin - adverse effects"

Dose-escalation and pharmacokinetic study of nanoparticle curcumin, a potential anticancer agent with improved bioavailability, in healthy human volunteers by Kanai, Masashi, Imaizumi, Atsushi, Otsuka, Yoshihiko, Sasaki, Hiroki, Hashiguchi, Momo, Tsujiko, Kazu, Matsumoto, Shigemi, Ishiguro, Hiroshi, Chiba, Tsutomu

“… After an interval of 2 weeks, the same subjects then received THERACURMIN at a single dose of 210…”
Get full text

oral bioavailability of curcumin from micronized powder and liquid micelles is significantly increased in healthy humans and differs between sexes by Schiborr, Christina, Kocher, Alexa, Behnam, Dariush, Jandasek, Josef, Toelstede, Simone, Frank, Jan

“… METHODS AND RESULTS: In this crossover study, healthy subjects (13 women, 10 men) took, in random order, a single oral dose of 500 mg curcuminoids as native powder, micronized powder, or liquid micelles…”
Get full text

Potential of Curcumin in Skin Disorders by Vollono, Laura, Falconi, Mattia, Gaziano, Roberta, Iacovelli, Federico, Dika, Emi, Terracciano, Chiara, Bianchi, Luca, Campione, Elena

“…Curcumin is a compound isolated from turmeric, a plant known for its medicinal use. Recently, there is a growing interest in the medical community in…”
Get full text

Efficacy and Safety of Phytosomal Curcumin in Non-Alcoholic Fatty Liver Disease: A Randomized Controlled Trial by Panahi, Yunes, Kianpour, Parisa, Mohtashami, Reza, Jafari, Ramezan, Simental-Mendía, Luis E., Sahebkar, Amirhossein

“… This study aimed to evaluate the efficacy and safety of supplementation with phytosomal curcumin in subjects with NAFLD…”
Get full text

Eight Weeks of a High Dose of Curcumin Supplementation May Attenuate Performance Decrements Following Muscle-Damaging Exercise by Jäger, Ralf, Purpura, Martin, Kerksick, Chad M.

“…Background: It is known that unaccustomed exercise—especially when it has an eccentric component—causes muscle damage and subsequent performance decrements…”
Get full text

ProspeCtive study to evaluate efficacy, safety and tOlerability of dietary supplemeNT of Curcumin (BCM95) in subjects with Active relapsing MultIple Sclerosis treated with subcutaNeous Interferon beta 1a 44 mcg TIW (CONTAIN): A randomized, controlled trial by Petracca, Maria, Quarantelli, Mario, Moccia, Marcello, Vacca, Giovanni, Satelliti, Barbara, D'Ambrosio, Gianluigi, Carotenuto, Antonio, Ragucci, Monica, Assogna, Francesco, Capacchione, Antonio, Lanzillo, Roberta, Morra, Vincenzo Brescia

“… Here we investigated the efficacy of curcumin, a naturally occurring poly-phenolic phytochemical with potent anti-inflammatory and antioxidant properties, in subjects under treatment with IFN…”
Get full text

Short-term Curcuminoid Supplementation for Chronic Pulmonary Complications due to Sulfur Mustard Intoxication: Positive Results of a Randomized Double-blind Placebo-controlled Trial by Panahi, Y, Ghanei, M, Bashiri, S, Hajihashemi, A, Sahebkar, A

“…). The present pilot study aimed to investigate the clinical effects of supplementation with curcuminoids on markers of pulmonary function and systemic inflammation in SM-intoxicated subjects…”
Get more information

Curcumin as a therapeutic agent: the evidence from in vitro, animal and human studies by Epstein, Jenny, Sanderson, Ian R., MacDonald, Thomas T.

“… Curcumin is non-toxic to human subjects at high doses. It is a complex molecule with multiple biological targets and different cellular effects…”
Get full text

A Randomized Double-Blind Placebo-Controlled Phase IIB Trial of Curcumin in Oral Leukoplakia by Kuriakose, Moni Abraham, Ramdas, Kunnambath, Dey, Bindu, Iyer, Subramanya, Rajan, Gunaseelan, Elango, Kalavathy K, Suresh, Amritha, Ravindran, Divya, Kumar, Rajneesh R, R, Prathiba, Ramachandran, Surya, Kumar, Nisha Asok, Thomas, Gigi, Somanathan, Thara, Ravindran, Hiran K, Ranganathan, Kannan, Katakam, Sudhakar Babu, Parashuram, Shivashankar, Jayaprakash, Vijayvel, Pillai, M Radhakrishna

“… Subjects with oral leukoplakia (n = 223) were randomized (1:1 ratio) to receive orally, either…”
Get more information

A combination of hydroxytyrosol, omega-3 fatty acids and curcumin improves pain and inflammation among early stage breast cancer patients receiving adjuvant hormonal therapy: results of a pilot study by Martínez, N., Herrera, M., Frías, L., Provencio, M., Pérez-Carrión, R., Díaz, V., Morse, Michael, Crespo, M. C.

“…Purpose Breast cancer patients receiving hormonal therapies face risks of relapse, increased rates of cardiovascular events, and toxicities of therapy such as…”
Get full text

Efficacy and safety of curcumin in primary sclerosing cholangitis: an open label pilot study by Eaton, John E., Nelson, Kevin M., Gossard, Andrea A., Carey, Elizabeth J., Tabibian, James H, Lindor, Keith D., LaRusso, Nicholas F.

“…Goals: To assess if curcumin improves markers of cholestasis among subjects with primary sclerosing cholangitis (PSC). Background…”
Get full text

Safety, tolerability and pharmacokinetics of liposomal curcumin in healthy humans by Storka, Angela, Vcelar, Brigitta, Klickovic, Uros, Gouya, Ghazaleh, Weisshaar, Stefan, Aschauer, Stefan, Bolger, Gordon, Helson, Lawrence, Wolzt, Michael

“… In this phase I clinical trial we investigated the pharmacokinetics, safety, and tolerability of intravenously administered liposomal curcumin in healthy subjects…”
Get more information

Human Pharmacokinetics of High Dose Oral Curcumin and Its Effect on Heme Oxygenase-1 Expression in Healthy Male Subjects by Klickovic, Uros, Doberer, Daniel, Gouya, Ghazaleh, Aschauer, Stefan, Weisshaar, Stefan, Storka, Angela, Bilban, Martin, Wolzt, Michael

“… We investigated the inducibility of HO-1 by orally administered curcumin in healthy male subjects and its correlation with the GT length polymorphism. Methods…”
Get full text

Sensitization of GSH synthesis by curcumin curtails acrolein-induced alveolar epithelial apoptosis via Keap1 cysteine conjugation: A randomized controlled trial and experimental animal model of pneumonitis by Hee Jo, Eun, Eun Moon, Ji, Han Chang, Moon, Jin Lim, Ye, Hyun Park, Jung, Hee Lee, Suk, Rae Cho, Young, Cho, Art E, Pil Pack, Seung, Kim, Hyeon-Wee, Crowley, Liana, Le, Brandy, Nukhet, Aykin-Burns, Chen, Yinfeng, Zhong, Yihang, Zhao, Jiangchao, Li, Ying, Cha, Hanvit, Hoon Pan, Jeong, Kyeom Kim, Jae, Hyup Lee, Jin

“…[Display omitted] •Curcumin improves systemic inflammation in subjects residing in an air-polluted area…”
Get full text

Curcumin effects on blood lipid profile in a 6-month human study by Baum, Larry, Cheung, Stanley K.K., Mok, Vincent C.T., Lam, Linda C.W., Leung, Vivian P.Y., Hui, Elsie, Ng, Chelsia C.Y., Chow, Moses, Ho, Ping C., Lam, Sherry, Woo, Jean, Chiu, Helen F.K., Goggins, William, Zee, Benny, Wong, Adrian, Mok, Hazel, Cheng, William K.F., Fong, Carmen, Lee, Jenny S.W., Chan, Ming-Houng, Szeto, Samuel S.L., Lui, Victor W.C., Tsoh, Joshua, Kwok, Timothy C.Y., Chan, Iris H.S., Lam, Christopher W.K.

“… This study investigated the effects of consuming curcumin on the serum lipid profile in men and women. Elderly subjects ( n = 36…”
Get full text

A randomized, placebo-controlled, double-blind clinical trial of curcuminoids in oral lichen planus by Chainani-Wu, N., Silverman, S., Reingold, A., Bostrom, A., Mc Culloch, C., Lozada-Nur, F., Weintraub, J.

“… The first interim analysis was conducted in October 2004 using data from the first 33 subjects…”
Get full text

Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa) by Chainani-Wu, Nita

“…Tumeric is a spice that comes from the root Curcuma longa, a member of the ginger family, Zingaberaceae. In Ayurveda (Indian traditional medicine), tumeric has…”
Get more information