Výsledky vyhľadávania - "Critical reviews in oncology/hematology"

cAMP-dependent protein kinase: role in normal and malignant growth Autor Cho-Chung, Yoon S., Pepe, Stefano, Clair, Timothy, Budillon, AlfreD.O., Nesterova, Maria

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Anti-hypertensive drugs and skin cancer risk: a review of the literature and meta-analysis Autor Gandini, Sara, Palli, Domenico, Spadola, Giuseppe, Bendinelli, Benedetta, Cocorocchio, Emilia, Stanganelli, Ignazio, Miligi, Lucia, Masala, Giovanna, Caini, Saverio

“…•Long-term users of photosensitizing drugs might be at increased skin cancer risk.•We reviewed studies focusing on skin cancer risk among anti-hypertensives…”
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Meta-analysis of immune-related adverse events in phase 3 clinical trials assessing immune checkpoint inhibitors for lung cancer Autor Berti, Alvise, Bortolotti, Roberto, Dipasquale, Mariachiara, Kinspergher, Stefania, Prokop, Larry, Grandi, Guido, Inchiostro, Sandro, Paolazzi, Giuseppe, Caffo, Orazio, Veccia, Antonello

“…•This meta-analysis of immune-related adverse events (irAEs) of checkpoint inhibitors (ICIs) in lung cancer showed that immunotherapy is associated with a…”
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Triplet (FOLFOXIRI) versus doublet (FOLFOX or FOLFIRI) backbone chemotherapy as first-line treatment of metastatic colorectal cancer: A systematic review and meta-analysis Autor Marques, Rui Pedro, Duarte, Gonçalo S., Sterrantino, Carmelo, Pais, Helena Luna, Quintela, António, Martins, Ana Paula, Costa, João

“…•Uncertainty exists regarding initial chemotherapy for metastatic colorectal cancer.•Recent trials with FOLFOXIRI suggest it could be an important alternative…”
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Targeting immune suppressing myeloid-derived suppressor cells in oncology Autor Kao, Johnny, Ko, Eric C., Eisenstein, Samuel, Sikora, Andrew G., Fu, Shibo, Chen, Shu-hsia

“…Emerging data suggests that host immune cells with a suppressive phenotype represent a significant hurdle to successful therapy for metastatic cancer. Among…”
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Fertility management for malignant ovarian germ cell tumors patients Autor Di Tucci, Chiara, Casorelli, Assunta, Morrocchi, Elisa, Palaia, Innocenza, Muzii, Ludovico, Panici, Pierluigi Benedetti

“…•Fertility management of patients with malignant ovarian germ cell cancer.•Patients with malignant ovarian germ cell cancer underwent surgical and/or medical…”
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Developing drugs in cancer-related bone pain Autor Lucchesi, Maurizio, Lanzetta, Gaetano, Antonuzzo, Andrea, Rozzi, Antonio, Sardi, Iacopo, Favre, Claudio, Ripamonti, Carla Ida, Santini, Daniele, Armento, Grazia

“…•About 75% of patients with bone involvement is interested by pain.•Cancer-related bone pain has both a nociceptive and a neuropathic component.•Cancer-related…”
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Breast metastases from oligodendroglioma: An unusual extraneural spread in two young women and a review of the literature Autor Mazza, E., Belli, C., Terreni, M., Doglioni, C., Losio, C., Cantore, M., Mambrini, A., Reni, M.

“…Extraneural dissemination of oligodendroglioma is rare. Cases of breast metastases have never been described in the literature. We report the first two cases…”
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Tissue and serum biomarkers as prognostic variables in endometrioid-type endometrial cancer Autor Gadducci, Angiolo, Cosio, Stefania, Genazzani, Andrea Riccardo

“…FIGO stage, tumor grade, depth of myometrial invasion, lymph-vascular space status and lymph node status are the most important clinical-pathological…”
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Unmet supportive care needs of people with advanced cancer and their caregivers: A systematic scoping review Autor Hart, Nicolas H., Crawford-Williams, Fiona, Crichton, Megan, Yee, Jasmine, Smith, Thomas J., Koczwara, Bogda, Fitch, Margaret I., Crawford, Gregory B., Mukhopadhyay, Sandip, Mahony, Jane, Cheah, Chan, Townsend, James, Cook, Olivia, Agar, Meera R., Chan, Raymond J.

“…Examining and addressing unmet care needs is integral to improving the provision and quality of cancer services. This review explored the prevalence of unmet…”
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TMB or not TMB as a biomarker: That is the question Autor Addeo, Alfredo, Friedlaender, Alex, Banna, Giuseppe L., Weiss, Glen J.

“…[Display omitted] •Immune checkpoint inhibitors (ICIs) have revolutionized the landscape of therapeutic options for many cancers.•The only biomarker predictive…”
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Matrix metalloproteinases participation in the metastatic process and their diagnostic and therapeutic applications in cancer Autor Gonzalez-Avila, Georgina, Sommer, Bettina, Mendoza-Posada, Daniel A., Ramos, Carlos, Garcia-Hernandez, A. Armando, Falfan-Valencia, Ramces

“…Matrix metalloproteinases (MMPs) participate from the initial phases of cancer onset to the settlement of a metastatic niche in a second organ. Their role in…”
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The impact of gender on The efficacy of immune checkpoint inhibitors in cancer patients: The MOUSEION-01 study Autor Santoni, Matteo, Rizzo, Alessandro, Mollica, Veronica, Matrana, Marc R., Rosellini, Matteo, Faloppi, Luca, Marchetti, Andrea, Battelli, Nicola, Massari, Francesco

“…[Display omitted] •Previous studies and meta-analysis have suggested the possible existence of sex-related differences in response to immunotherapy.•We…”
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Mechanistic role of HPV-associated early proteins in cervical cancer: Molecular pathways and targeted therapeutic strategies Autor Bhattacharjee, Rahul, Das, Sabya Sachi, Biswal, Smruti Sudha, Nath, Arijit, Das, Debangshi, Basu, Asmita, Malik, Sumira, Kumar, Lamha, Kar, Sulagna, Singh, Sandeep Kumar, Upadhye, Vijay Jagdish, Iqbal, Danish, Almojam, Suliman, Roychoudhury, Shubhadeep, Ojha, Shreesh, Ruokolainen, Janne, Jha, Niraj Kumar, Kesari, Kavindra Kumar

“…Cervical cancer (CC), one of the major causes of death of women throughout the world is primarily caused due to Human Papilloma Virus (HPV) 16 and 18. The…”
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Cancer patients and research during COVID-19 pandemic: A systematic review of current evidence Autor Moujaess, Elissar, Kourie, Hampig Raphael, Ghosn, Marwan

“…The novel coronavirus, also known as SARS-Cov-2 or COVID-19 has become a worldwide threat and the major healthcare concern of the year 2020. Cancer research…”
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New advances in exosome-based targeted drug delivery systems Autor Ferreira, Débora, Moreira, João Nuno, Rodrigues, Lígia R.

“…In recent years, various drug nano-delivery platforms have emerged to enhance drug effectiveness in cancer treatment. However, their successful translation to…”
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The clinical use of circulating tumor cells (CTCs) enumeration for staging of metastatic breast cancer (MBC): International expert consensus paper Autor Cristofanilli, Massimo, Pierga, Jean-Yves, Reuben, James, Rademaker, Alfred, Davis, Andrew A., Peeters, Dieter J., Fehm, Tanja, Nolé, Franco, Gisbert-Criado, Rafael, Mavroudis, Dimitrios, Grisanti, Salvatore, Giuliano, Mario, Garcia-Saenz, Jose A., Stebbing, Justin, Caldas, Carlos, Gazzaniga, Paola, Manso, Luis, Zamarchi, Rita, de Lascoiti, Angela Fernandez, De Mattos-Arruda, Leticia, Ignatiadis, Michail, Cabel, Luc, van Laere, Steven J., Meier-Stiegen, Franziska, Sandri, Maria-Teresa, Vidal-Martinez, Jose, Politaki, Eleni, Consoli, Francesca, Generali, Daniele, Cappelletti, Maria Rosa, Diaz-Rubio, Eduardo, Krell, Jonathan, Dawson, Sarah-Jane, Raimondi, Cristina, Rutten, Annemie, Janni, Wolfgang, Munzone, Elisabetta, Carañana, Vicente, Agelaki, Sofia, Almici, Camillo, Dirix, Luc, Solomayer, Erich-Franz, Zorzino, Laura, Darrigues, Lauren, Reis-Filho, Jorge S., Gerratana, Lorenzo, Michiels, Stefan, Bidard, François-Clément, Pantel, Klaus

“…The heterogeneity of metastatic breast cancer (MBC) necessitates novel biomarkers allowing stratification of patients for treatment selection and drug…”
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Lung cancer in never smokers: The role of different risk factors other than tobacco smoking Autor Corrales, Luis, Rosell, Rafael, Cardona, Andrés F., Martín, Claudio, Zatarain-Barrón, Zyanya Lucia, Arrieta, Oscar

“…Lung cancer (LC), the leading cause of cancer-related deaths worldwide, is a complex and highly heterogeneous disease. Additional to its biological complexity,…”
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The Wnt signaling pathway in cancer Autor Duchartre, Yann, Kim, Yong-Mi, Kahn, Michael

“…The Wnt signaling pathway is critically involved in both the development and homeostasis of tissues via regulation of their endogenous stem cells. Aberrant Wnt…”
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The systemic inflammation-based neutrophil–lymphocyte ratio: Experience in patients with cancer Autor Guthrie, Graeme J.K., Charles, Kellie A., Roxburgh, Campbell S.D., Horgan, Paul G., McMillan, Donald C., Clarke, Stephen J.

“…There is increasing and consistent evidence that cancer-associated inflammation is a key determinant of outcome in patients with cancer. Various markers of…”
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