Suchergebnisse - "Cosgrove, Jason"

B cell zone reticular cell microenvironments shape CXCL13 gradient formation von Cosgrove, Jason, Novkovic, Mario, Albrecht, Stefan, Pikor, Natalia B., Zhou, Zhaoukun, Onder, Lucas, Mörbe, Urs, Cupovic, Jovana, Miller, Helen, Alden, Kieran, Thuery, Anne, O’Toole, Peter, Pinter, Rita, Jarrett, Simon, Taylor, Emily, Venetz, Daniel, Heller, Manfred, Uguccioni, Mariagrazia, Legler, Daniel F., Lacey, Charles J., Coatesworth, Andrew, Polak, Wojciech G., Cupedo, Tom, Manoury, Bénedicte, Thelen, Marcus, Stein, Jens V., Wolf, Marlene, Leake, Mark C., Timmis, Jon, Ludewig, Burkhard, Coles, Mark C.

“… Through the formation of concentration gradients, morphogens drive graded responses to extracellular signals, thereby fine-tuning cell behaviors in complex …”
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Selective withdrawal of a three-layer viscous fluid von West, Lachlan, Cosgrove, Jason M., Bassom, Andrew P.

“… Two dimensional, selective withdrawal of a three-layer fluid in a rectangular tank is considered. Each fluid is viscous, weakly compressible and miscible. The …”
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DRAG in situ barcoding reveals an increased number of HSPCs contributing to myelopoiesis with age von Urbanus, Jos, Cosgrove, Jason, Beltman, Joost B., Elhanati, Yuval, Moral, Rafael A., Conrad, Cecile, van Heijst, Jeroen W., Tubeuf, Emilie, Velds, Arno, Kok, Lianne, Merle, Candice, Magnusson, Jens P., Guyonnet, Léa, Frisén, Jonas, Fre, Silvia, Walczak, Aleksandra M., Mora, Thierry, Jacobs, Heinz, Schumacher, Ton N., Perié, Leïla

“… Ageing is associated with changes in the cellular composition of the immune system. During ageing, hematopoietic stem and progenitor cells (HSPCs) that produce …”
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Erythropoietin directly remodels the clonal composition of murine hematopoietic multipotent progenitor cells von Eisele, Almut S, Cosgrove, Jason, Magniez, Aurelie, Tubeuf, Emilie, Tenreira Bento, Sabrina, Conrad, Cecile, Cayrac, Fanny, Tak, Tamar, Lyne, Anne-Marie, Urbanus, Jos, Perié, Leïla

“… The cytokine erythropoietin (EPO) is a potent inducer of erythrocyte development and one of the most prescribed biopharmaceuticals. The action of EPO on …”
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High-Speed Single-Molecule Tracking of CXCL13 in the B-Follicle von Miller, Helen, Cosgrove, Jason, Wollman, Adam J. M., Taylor, Emily, Zhou, Zhaokun, O’Toole, Peter J., Coles, Mark C., Leake, Mark C.

“… Soluble factors are an essential means of communication between cells and their environment. However, many molecules readily interact with extracellular matrix …”
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Simulating CXCR5 Dynamics in Complex Tissue Microenvironments von Cosgrove, Jason, Alden, Kieran, Stein, Jens V., Coles, Mark C., Timmis, Jon

“… To effectively navigate complex tissue microenvironments, immune cells sense molecular concentration gradients using G-protein coupled receptors. However, due …”
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CellDestiny: A RShiny application for the visualization and analysis of single-cell lineage tracing data von Hadj Abed, Louisa, Tak, Tamar, Cosgrove, Jason, Perié, Leïla

“… Single-cell lineage tracing permits the labeling of individual cells with a heritable marker to follow the fate of each cell’s progeny. Over the last twenty …”
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Nonlinear behaviour of interacting mid-latitude atmospheric vortices von Cosgrove, Jason M., Forbes, Lawrence K.

“… Nonlinear behaviour of interacting large-scale atmospheric vortices is considered. These vortices are approximately fifteen kilometres high and can have …”
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A line vortex in a two-fluid system von Forbes, Lawrence K., Cosgrove, Jason M.

“… This paper considers the classical problem of a line vortex in planar flow of a fluid. However, an interface is present at some finite radius from the line …”
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Parathyroid hormone-related protein maintains mammary epithelial fate and triggers nipple skin differentiation during embryonic breast development von Foley, J, Dann, P, Hong, J, Cosgrove, J, Dreyer, B, Rimm, D, Dunbar, M, Philbrick, W, Wysolmerski, J

“… Prior reports have demonstrated that both parathyroid hormone-related protein (PTHrP) and the type I PTH/PTHrP receptor are necessary for the proper …”
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3058 – METABOLIC HETEROGENEITY IN HEMATOPOIETIC STEM AND PROGENITOR CELLS FUELS INNATE IMMUNITY von Cosgrove, Jason, Perie, Leila

“… Recent technical advances permit metabolic profiling at the single-cell level but existing methods are destructive, making it difficult to link metabolic state …”
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Surgical salvage therapy for malignant intrathoracic metastases from nonseminomatous germ cell cancer of testicular origin: analysis of a single-institution experience von Kesler, Kenneth A, Wilson, Jamison L, Cosgrove, Jason A, Brooks, Jo Ann, Messiha, Ahdy, Fineberg, Naomi S, Einhorn, Lawrence H, Brown, John W

“… Cisplatin-based chemotherapy followed by surgical extirpation of residual benign disease represents the usual sequence of curative therapy for metastatic …”
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SELECTIVE WITHDRAWAL OF A TWO-LAYER VISCOUS FLUID von COSGROVE, JASON M., FORBES, LAWRENCE K.

“… Selective withdrawal of a two-layer fluid is considered. The fluid layers are weakly compressible, miscible and viscous and therefore flow rotationally. The …”
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3101 – HEMATOPOIESIS IN NUMBERS von Hustin, Lucie, Cosgrove, Jason, de Boer, Rob, Perié, Leïla

“… Hematopoiesis is a dynamic process in which stem and progenitor cells give rise to the ∼10^13 blood and immune cells distributed throughout the human body. We …”
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Using Emulation to Engineer and Understand Simulations of Biological Systems von Alden, Kieran, Cosgrove, Jason, Coles, Mark, Timmis, Jon

“… Modeling and simulation techniques have demonstrated success in studying biological systems. As the drive to better capture biological complexity leads to more …”
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Breast cancer remotely imposes a myeloid bias on haematopoietic stem cells by reprogramming the bone marrow niche von Gerber-Ferder, Yohan, Cosgrove, Jason, Duperray-Susini, Aleria, Missolo-Koussou, Yoann, Dubois, Marine, Stepaniuk, Kateryna, Pereira-Abrantes, Manuela, Sedlik, Christine, Lameiras, Sonia, Baulande, Sylvain, Bendriss-Vermare, Nathalie, Guermonprez, Pierre, Passaro, Diana, Perié, Leïla, Piaggio, Eliane, Helft, Julie

“… Myeloid cell infiltration of solid tumours generally associates with poor patient prognosis and disease severity 1 – 13 . Therefore, understanding the …”
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Hematopoiesis in numbers von Cosgrove, Jason, Hustin, Lucie S.P., de Boer, Rob J., Perié, Leïla

“… Hematopoiesis is a dynamic process in which stem and progenitor cells give rise to the ~1013 blood and immune cells distributed throughout the human body. We …”
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3130 – COMBINED SINGLE CELL PROFILING AND IN VIVO LINEAGE TRACING REVEALS THE HEMATOPOIETIC DYNAMICS AFTER CHEMOTHERAPY von Midoun, Adil, Tubeuf, Emilie, Cosgrove, Jason, Bento, Sabrina Tenreira, Conrad, Cécile, Duperray-Susini, Aléria, Passaro, Diana, Vargaftig, Jacques, Perié, Leïla

“… Chemotherapy for non-hematological cancers can place significant stress on the Hematopoietic Stem and Progenitor Cells (HSPCs), potentially leading to severe …”
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3130 – COMBINED SINGLE CELL PROFILING AND I N VIVO LINEAGE TRACING REVEALS THE HEMATOPOIETIC DYNAMICS AFTER CHEMOTHERAPY von Midoun, Adil, Tubeuf, Emilie, Cosgrove, Jason, Bento, Sabrina Tenreira, Conrad, Cécile, Duperray-Susini, Aléria, Passaro, Diana, Vargaftig, Jacques, Perié, Leïla

“… Chemotherapy for non-hematological cancers can place significant stress on the Hematopoietic Stem and Progenitor Cells (HSPCs), potentially leading to severe …”
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Natural Killer Cell-Mediated Cytotoxicity Shapes the Clonal Evolution of B-cell Leukemia von Buri, Michelle C, Shoeb, Mohamed R, Bykov, Aleksandr, Repiscak, Peter, Baik, Hayeon, Dupanovic, Alma, David, Faith O, Kovacic, Boris, Hall-Glenn, Faith, Dopa, Sara, Urbanus, Jos, Sippl, Lisa, Stofner, Susanne, Emminger, Dominik, Cosgrove, Jason, Schinnerl, Dagmar, Poetsch, Anna R, Lehner, Manfred, Koenig, Xaver, Perié, Leïla, Schumacher, Ton N, Gotthardt, Dagmar, Halbritter, Florian, Putz, Eva M

“… The term cancer immunoediting describes the dual role by which the immune system can suppress and promote tumor growth and is divided into three phases: …”
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