Výsledky vyhľadávania - "Complement component C3"

Human complement component C3 N-glycome changes in type 1 diabetes complications Autor Šoić, Dinko, Štambuk, Jerko, Tijardović, Marko, Keser, Toma, Lauc, Gordan, Bulum, Tomislav, Lovrenčić, Marijana Vučić, Rebrina, Sandra Vučković, Tomić, Martina, Novokmet, Mislav, Smirčić-Duvnjak, Lea, Gornik, Olga

“… Moreover, the role of complement component C3 in diabetic nephropathy and retinopathy has been implicated, and C3 N-glycome was found to be altered in young T1D patients…”
Získať plný text

Gender differences on oxidative stress markers and complement component C3 plasma values after an oral unsaturated fat load test Autor Ferri, Jordi, Navarro, Inmaculada, Alabadí, Blanca, Bosch-Sierra, Neus, Benito, Esther, Civera, Miguel, Ascaso, Juan F, Martinez-Hervas, Sergio, Real, Jose T

“…Post-prandial lipaemia (PL), oxidative stress (OS), and complement component C3 (C3) values are related to the atherosclerosis process…”
Zistit podrobnosti o prístupe

Gender differences on oxidative stress markers and complement component C3 plasma values after an oral unsaturated fat load test Autor Ferri, Jordi, Navarro, Inmaculada, Alabadí, Blanca, Bosch-Sierra, Neus, Benito, Esther, Civera, Miguel, Ascaso, Juan F., Martinez-Hervas, Sergio, Real, Jose T.

“…Post-prandial lipaemia (PL), oxidative stress (OS), and complement component C3 (C3) values are related to the atherosclerosis process…”
Získať plný text

Complement Component C3 Variant (R102G) and the Risk of Neovascular Age-Related Macular Degeneration in a Tunisian Population Autor Habibi, Imen, Sfar, Imen, Kort, Fedra, Bouraoui, Rim, Chebil, Ahmed, Limaiem, Rim, Ayed, Saloua, Ben Abdallah, Taïeb, El Matri, Leila, Gorgi, Yousr

“…) in 207 control subjects free of any eye disease (fundus normal) and 145 patients with exudative AMD…”
Zistit podrobnosti o prístupe

C3 inhibition with pegcetacoplan in subjects with paroxysmal nocturnal hemoglobinuria treated with eculizumab Autor Castro, Carlos, Grossi, Federico, Weitz, Ilene Ceil, Maciejewski, Jaroslaw, Sharma, Vivek, Roman, Eloy, Brodsky, Robert A., Tan, Lisa, Di Casoli, Carl, El Mehdi, Delphine, Deschatelets, Pascal, Francois, Cedric

“…‐label, phase Ib study was designed to assess the safety, tolerability, and pharmacokinetics of pegcetacoplan in subjects with PNH who remained anemic during treatment with eculizumab…”
Získať plný text

Efficacy and Safety of Abatacept in Lupus Nephritis: A Twelve‐Month, Randomized, Double‐Blind Study Autor Furie, Richard, Nicholls, Kathy, Cheng, Tien‐Tsai, Houssiau, Frederic, Burgos‐Vargas, Ruben, Chen, Shun‐Le, Hillson, Jan L., Meadows‐Shropshire, Stephanie, Kinaszczuk, Michael, Merrill, Joan T.

“…Objective To compare the efficacy and safety of intravenous (IV) abatacept, a selective T cell costimulation modulator, versus placebo for the treatment of…”
Získať plný text

Plasma proteomics identify biomarkers predicting Parkinson’s disease up to 7 years before symptom onset Autor Hällqvist, Jenny, Bartl, Michael, Dakna, Mohammed, Schade, Sebastian, Garagnani, Paolo, Bacalini, Maria-Giulia, Pirazzini, Chiara, Bhatia, Kailash, Schreglmann, Sebastian, Xylaki, Mary, Weber, Sandrina, Ernst, Marielle, Muntean, Maria-Lucia, Sixel-Döring, Friederike, Franceschi, Claudio, Doykov, Ivan, Śpiewak, Justyna, Vinette, Héloїse, Trenkwalder, Claudia, Heywood, Wendy E., Mills, Kevin, Mollenhauer, Brit

“…Parkinson’s disease is increasingly prevalent. It progresses from the pre-motor stage (characterised by non-motor symptoms like REM sleep behaviour disorder),…”
Získať plný text

Complement Activation via a C3a Receptor Pathway Alters CD4 + T Lymphocytes and Mediates Lung Cancer Progression Autor Kwak, Jeff W, Laskowski, Jennifer, Li, Howard Y, McSharry, Maria V, Sippel, Trisha R, Bullock, Bonnie L, Johnson, Amber M, Poczobutt, Joanna M, Neuwelt, Alexander J, Malkoski, Stephen P, Weiser-Evans, Mary C, Lambris, John D, Clambey, Eric T, Thurman, Joshua M, Nemenoff, Raphael A

“…), with tumors undetectable in many subjects. Growth inhibition was associated with increased numbers of IFNγ /TNFα…”
Zistit podrobnosti o prístupe

Coagulation factors induce human skin mast cell and basophil degranulation via activation of complement 5 and the C5a receptor Autor Yanase, Yuhki, Matsuo, Yoshimi, Takahagi, Shunsuke, Kawaguchi, Tomoko, Uchida, Kazue, Ishii, Kaori, Tanaka, Akio, Matsubara, Daiki, Ozawa, Koichiro, Hide, Michihiro

“…Because serine proteases, such as coagulation and/or fibrinolysis factors, may convert C5 into C5a and C5b, we investigated the effect of C5 in the presence of…”
Získať plný text

Type 1 interferon mediates chronic stress-induced neuroinflammation and behavioral deficits via complement component 3-dependent pathway Autor Tripathi, Ashutosh, Whitehead, Carl, Surrao, Katelyn, Pillai, Ananya, Madeshiya, Amit, Li, Yong, Khodadadi, Hesam, Ahmed, Anthony O, Turecki, Gustavo, Baban, Babak, Pillai, Anilkumar

“…Chronic stress is a major risk factor in the pathophysiology of many neuropsychiatric disorders. Further, chronic stress conditions can promote…”
Získať plný text

Salivary Proteomics for Detecting Novel Biomarkers of Periodontitis: A Systematic Review Autor Corana, Matteo, Baima, Giacomo, Iaderosa, Giovanni, Franco, Francesco, Zhang, Jianjian, Berta, Giovanni Nicolao, Romano, Federica, Aimetti, Mario

“… and gingivitis subjects, as well as to provide a qualitative methodological assessment of the current literature…”
Získať plný text

The gut microbiome regulates astrocyte reaction to Aβ amyloidosis through microglial dependent and independent mechanisms Autor Chandra, Sidhanth, Di Meco, Antonio, Dodiya, Hemraj B., Popovic, Jelena, Cuddy, Leah K., Weigle, Ian Q., Zhang, Xiaoqiong, Sadleir, Katherine, Sisodia, Sangram S., Vassar, Robert

“… + astrocytes, plaque-associated astrocytes (PAA), PAA morphological parameters, and astrocyte complement component C3 levels were quantified using a combination of immunohistochemistry, immunoblotting, widefield microscopy, and confocal microscopy…”
Získať plný text

Complement activation in polycystic ovary syndrome occurs in the postprandial and fasted state and is influenced by obesity and insulin sensitivity Autor Lewis, Ruth D., Narayanaswamy, Anil K., Farewell, Daniel, Rees, Dafydd Aled

“… Complement activation post‐oral fat tolerance test (OFTT) was compared in 40 additional subjects…”
Získať plný text

POS1178 IDENTIFYING THE NEW DISORDER “IDIOPATHIC HYPOCRYOGLOBULINAEMIA” IN PATIENTS WITH PREVIOUSLY UNIDENTIFIED CLINICAL CONDITIONS Autor Roccatello, D., Sciascia, S., Naretto, C., Barreca, A., Solfietti, L., Battaglia, L., Viziello, L., Fenoglio, R., Rossi, D.

“…BackgroundA considerable number of patients with high clinical suspicion for cryoglobulinaemic vasculitis either.show negative results for the detection of…”
Získať plný text

AB1496 MICROCIRCULATION CHARACTERIZATION IN ANOREXIA NERVOSA PATIENTS WITH RAYNAUD’S PHENOMENON Autor Natalello, G., Zoli, A., Cerasuolo, P. G., Murro, S. DI, Alonzi, G., Fiore, S., Boni, V., De Lorenzis, E., Policola, C., Moccia, L., Anesini, M. B., Rinaldi, L., Sani, G., Pontecorvi, A., D’agostino, M. A., Bosello, S. L.

“…) were recruited among female subjects with a body mass index (BMI) >20 kg/m2 undergoing screening NVC due to RP and no concomitant rheumatic disease (primary RP…”
Získať plný text

Association between hemoglobin glycation index with insulin resistance and carotid atherosclerosis in non-diabetic individuals Autor Marini, Maria Adelaide, Fiorentino, Teresa Vanessa, Succurro, Elena, Pedace, Elisabetta, Andreozzi, Francesco, Sciacqua, Angela, Perticone, Francesco, Sesti, Giorgio

“… and it has been found to be positively associated with micro- and macro-vascular complications in subjects with type 2 diabetes…”
Získať plný text

Janus kinase 1/2 inhibition for the treatment of autoinflammation associated with heterozygous TNFAIP3 mutation Autor Mulhern, Ciara M., Hong, Ying, Omoyinmi, Ebun, Jacques, Thomas S., D'Arco, Felice, Hemingway, Cheryl, Brogan, Paul A., Eleftheriou, Despina

“…, TNF, IL-6, and monocyte chemoattractant protein 1 (MCP-1) in the brain.3 CNS involvement as the sole clinical manifestation of heterozygous TNFAIP3 variants in human subjects has never been described…”
Získať plný text

Dendritic spine loss in epileptogenic Type II focal cortical dysplasia: Role of enhanced classical complement pathway activation Autor Rossini, Laura, De Santis, Dalia, Cecchini, Erica, Cagnoli, Cinzia, Maderna, Emanuela, Cartelli, Daniele, Morgan, Bryan Paul, Torvell, Megan, Spreafico, Roberto, Giacomo, Roberta, Tassi, Laura, Curtis, Marco, Garbelli, Rita

“… Neocortical tissues were collected from 20 subjects, mainly adults with a mean age at surgery of 31…”
Získať plný text

High Prevalence and Disease Correlation of Autoantibodies Against p40 Encoded by Long Interspersed Nuclear Elements in Systemic Lupus Erythematosus Autor Carter, Victoria, LaCava, John, Taylor, Martin S., Liang, Shu Ying, Mustelin, Cecilia, Ukadike, Kennedy C., Bengtsson, Anders, Lood, Christian, Mustelin, Tomas

“…‐matched healthy subjects by immunoblotting and enzyme‐linked immunosorbent assay (ELISA). Preparations of p40 that also contained associated proteins were analyzed by immunoblotting…”
Získať plný text

Prolonged Prothrombotic Effects of Antecedent Hypoglycemia in Individuals With Type 2 Diabetes Autor Chow, Elaine, Iqbal, Ahmed, Walkinshaw, Emma, Phoenix, Fladia, Macdonald, Ian A, Storey, Robert F, Ajjan, Ramzi, Heller, Simon R

“…Hypoglycemia has been linked to persistent increases in cardiovascular (CV) mortality in type 2 diabetes after the event. Our aim was to examine acute and…”
Zistit podrobnosti o prístupe