Výsledky vyhledávání - "Cholangitis, Sclerosing etiology"

Primary sclerosing cholangitis – a comprehensive review Autor Karlsen, Tom H., Folseraas, Trine, Thorburn, Douglas, Vesterhus, Mette

“…Primary sclerosing cholangitis (PSC) is a rare disorder characterised by multi-focal bile duct strictures and progressive liver disease. Inflammatory bowel…”
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Primary sclerosing cholangitis Autor Dyson, Jessica K, Beuers, Ulrich, Jones, David E J, Lohse, Ansgar W, Hudson, Mark

“…Primary sclerosing cholangitis is a rare, chronic cholestatic liver disease characterised by intrahepatic or extrahepatic stricturing, or both, with bile duct…”
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Primary Sclerosing Cholangitis Autor Lazaridis, Konstantinos N, LaRusso, Nicholas F

“…This review summarizes the current understanding of primary sclerosing cholangitis, a persistent, progressive disease for which there is no definitive therapy…”
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British Society of Gastroenterology and UK-PSC guidelines for the diagnosis and management of primary sclerosing cholangitis Autor Chapman, Michael Huw, Thorburn, Douglas, Hirschfield, Gideon M, Webster, George G J, Rushbrook, Simon M, Alexander, Graeme, Collier, Jane, Dyson, Jessica K, Jones, David EJ, Patanwala, Imran, Thain, Collette, Walmsley, Martine, Pereira, Stephen P

“…These guidelines on the management of primary sclerosing cholangitis (PSC) were commissioned by the British Society of Gastroenterology liver section. The…”
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Liver — guardian, modifier and target of sepsis Autor Strnad, Pavel, Tacke, Frank, Koch, Alexander, Trautwein, Christian

“…Key Points The liver represents a key integrator of microbial responses During microbial infection, the liver switches from tolerogenic towards immunogenic…”
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Primary sclerosing cholangitis: what is new in the therapeutic landscape Autor Curto, Armando, Cristoferi, Laura, Carbone, Marco, Galli, Andrea, Invernizzi, Pietro

“…Primary sclerosing cholangitis (PSC) is a rare, chronic cholestatic liver disease affecting the intra- and extra-hepatic bile ducts, leading to progressive…”
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Absence of the intestinal microbiota exacerbates hepatobiliary disease in a murine model of primary sclerosing cholangitis Autor Tabibian, James H., O'Hara, Steven P., Trussoni, Christy E., Tietz, Pamela S., Splinter, Patrick L., Mounajjed, Taofic, Hagey, Lee R., LaRusso, Nicholas F.

“…Primary sclerosing cholangitis (PSC) is a chronic, idiopathic, fibroinflammatory cholangiopathy. The role of the microbiota in PSC etiopathogenesis may be…”
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Integrin αvβ6 critically regulates hepatic progenitor cell function and promotes ductular reaction, fibrosis, and tumorigenesis Autor Peng, Zhen‐Wei, Ikenaga, Naoki, Liu, Susan B., Sverdlov, Deanna Y., Vaid, Kahini A., Dixit, Richa, Weinreb, Paul H., Violette, Shelia, Sheppard, Dean, Schuppan, Detlef, Popov, Yury

“…Integrin αvβ6 is rapidly up‐regulated on cells of epithelial lineage during tissue injury, where one of its primary functions is activation of latent…”
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Primary sclerosing cholangitis Autor Hirschfield, Gideon M, Karlsen, Tom H, Lindor, Keith D, Adams, David H

“…Primary sclerosing cholangitis is the classic hepatobiliary manifestation of inflammatory bowel disease and is generally chronic and progressive. Patients…”
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Risk factors for recurrent primary sclerosing cholangitis after liver transplantation Autor Ravikumar, Reena, Tsochatzis, Emmanuel, Jose, Sophie, Allison, Michael, Athale, Anuja, Creamer, Felicity, Gunson, Bridget, Iyer, Vikram, Madanur, Mansoor, Manas, Derek, Monaco, Andrea, Mirza, Darius, Owen, Nicola, Roberts, Keith, Sen, Gourab, Srinivasan, Parthi, Wigmore, Stephen, Fusai, Giuseppe, Fernando, Bimbi, Burroughs, Andrew

“…The association between primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD) is well recognised. However, the relationship between IBD and…”
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Cholangiocyte senescence by way of N‐ras activation is a characteristic of primary sclerosing cholangitis Autor Tabibian, James H., O'Hara, Steven P., Splinter, Patrick L., Trussoni, Christy E., LaRusso, Nicholas F.

“…Primary sclerosing cholangitis (PSC) is an incurable cholangiopathy of unknown etiopathogenesis. Here we tested the hypothesis that cholangiocyte senescence is…”
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The First European Evidence-based Consensus on Extra-intestinal Manifestations in Inflammatory Bowel Disease Autor Harbord, Marcus, Annese, Vito, Vavricka, Stephan R, Allez, Matthieu, Barreiro-de Acosta, Manuel, Boberg, Kirsten Muri, Burisch, Johan, De Vos, Martine, De Vries, Anne-Marie, Dick, Andrew D, Juillerat, Pascal, Karlsen, Tom H, Koutroubakis, Ioannis, Lakatos, Peter L, Orchard, Tim, Papay, Pavol, Raine, Tim, Reinshagen, Max, Thaci, Diamant, Tilg, Herbert, Carbonnel, Franck

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A Pilot Integrative Analysis of Colonic Gene Expression, Gut Microbiota, and Immune Infiltration in Primary Sclerosing Cholangitis-Inflammatory Bowel Disease: Association of Disease With Bile Acid Pathways Autor Quraishi, Mohammed Nabil, Acharjee, Animesh, Beggs, Andrew D, Horniblow, Richard, Tselepis, Chris, Gkoutos, Georgios, Ghosh, Subrata, Rossiter, A E, Loman, Nicholas, van Schaik, Willem, Withers, David, Walters, Julian R F, Hirschfield, Gideon M, Iqbal, Tariq H

“…Abstract Background Although a majority of patients with PSC have colitis [PSC-IBD; primary sclerosing cholangitis-inflammatory bowel disease], this is…”
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Pathogenesis of primary sclerosing cholangitis and advances in diagnosis and management Autor Eaton, John E, Talwalkar, Jayant A, Lazaridis, Konstantinos N, Gores, Gregory J, Lindor, Keith D

“…Primary sclerosing cholangitis (PSC), first described in the mid-1850s, is a complex liver disease that is heterogeneous in its presentation. PSC is…”
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Cyclosporine vs. tacrolimus after liver transplantation for primary sclerosing cholangitis – a propensity score-matched intention-to-treat analysis Autor Åberg, Fredrik, Sallinen, Ville, Tuominen, Samuli, Adam, René, Karam, Vincent, Mirza, Darius, Heneghan, Michael A., Line, Pål-Dag, Bennet, William, Ericzon, Bo-Göran, Grat, Michal, Lodge, Peter, Rasmussen, Allan, Schmelzle, Moritz, Thorburn, Douglas, Fondevila, Constantino, Helanterä, Ilkka, Nordin, Arno

“…There is controversy regarding the optimal calcineurin inhibitor type after liver transplant(ation) (LT) for primary sclerosing cholangitis (PSC). We compared…”
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Role of intravenous ketamine in the pathogenesis of secondary sclerosing cholangitis in critically ill patients: perpetrator or innocent bystander? Answers provided by forensic toxicology Autor Leonhardt, Silke, Baumann, Sven, Jürgensen, Christian, Hüter, Lars, Leonhardt, Julia

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Primary sclerosing cholangitis in children with inflammatory bowel disease: An ESPGHAN position paper from the Hepatology Committee and the IBD Porto group Autor Rheenen, Patrick F., Kolho, Kaija‐Leena, Russell, Richard K., Aloi, Marina, Deganello, Annamaria, Hussey, Séamus, Junge, Norman, De Laffolie, Jan, Deneau, Mark R., Fitzpatrick, Emer, Griffiths, Anne M., Hojsak, Iva, Nicastro, Emanuele, Nita, Andreia, Pakarinen, Mikko, Ricciuto, Amanda, Ridder, Lissy, Sonzogni, Aurelio, Tenca, Andrea, Samyn, Marianne, Indolfi, Giuseppe

“…Objective We aimed to provide an evidence‐supported approach to diagnose, monitor, and treat children with inflammatory bowel disease (IBD) and primary…”
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Primary Sclerosing Cholangitis and Inflammatory Bowel Disease Autor Escobar, Jessica Colin, Pereyra, Maria Navarez, Abbass, Mohammad Ali

“…Primary sclerosing cholangitis (PSC) is a rare pathology seen in patients with inflammatory bowel disease (IBD), especially ulcerative colitis. PSC increases…”
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NADPH Oxidase: A Potential Therapeutic Target to Reduce Primary Sclerosis Cholangitis Following Liver Transplantation Autor Aliakbarian, Mohsen, Ashrafzadeh, Kiarash, Ferns, Gordon A, Hadian, Reyhaneh, Khodashahi, Rozita, Arjmand, Mohammad-Hassan

“…The molecular mechanisms and causes of primary sclerosis cholangitis (PSC) post-liver transplantation are still unclear. PSC is a progressive cholestatic…”
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Extraintestinal Manifestations of Pediatric Inflammatory Bowel Disease: Prevalence, Presentation, and Anti-TNF Treatment Autor Greuter, Thomas, Bertoldo, Fabio, Rechner, Roman, Straumann, Alex, Biedermann, Luc, Zeitz, Jonas, Misselwitz, Benjamin, Scharl, Michael, Rogler, Gerhard, Safroneeva, Ekaterina, Ali, Raja A R, Braegger, Christian, Heyland, Klaas, Mueller, Pascal, Nydegger, Andreas, Petit, Laetitia-Marie, Schibli, Susanne, Furlano, Raoul I, Spalinger, Johannes, Schäppi, Michela, Zamora, Samuel, Froehlich, Florian, Herzog, Denise, Schoepfer, Alain M, Vavricka, Stephan R

“…There is a paucity of data on extraintestinal manifestations (EIM) and their treatment in pediatric patients with inflammatory bowel disease (IBD). Since 2008,…”
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