Suchergebnisse - "Cheng, Zhou‐Li"

Itaconate inhibits TET DNA dioxygenases to dampen inflammatory responses von Chen, Lei-Lei, Morcelle, Carmen, Cheng, Zhou-Li, Chen, Xiufei, Xu, Yanping, Gao, Yajing, Song, Junbin, Li, Zhijun, Smith, Matthew D., Shi, Miao, Zhu, Yezhang, Zhou, Neng, Cheng, Meng, He, Chenxi, Liu, Kwei‐Yan, Lu, Guoping, Zhang, Lei, Zhang, Cheng, Zhang, Jinye, Sun, Yiping, Qi, Tuan, Lyu, Yingying, Ren, Zhi-Zhong, Tan, Xian-Ming, Yin, Jiayong, Lan, Fei, Liu, Ying, Yang, Hui, Qian, Maoxiang, Duan, Caiwen, Chang, Xing, Zhou, Yufeng, Shen, Li, Baldwin, Albert S., Guan, Kun-Liang, Xiong, Yue, Ye, Dan

“… As one of the most induced genes in activated macrophages, immune-responsive gene 1 ( IRG1 ) encodes a mitochondrial metabolic enzyme catalysing the production …”
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Metabolic reprogramming by PCK1 promotes TCA cataplerosis, oxidative stress and apoptosis in liver cancer cells and suppresses hepatocellular carcinoma von Liu, Meng-Xi, Jin, Lei, Sun, Si-Jia, Liu, Peng, Feng, Xu, Cheng, Zhou-Li, Liu, Wei-Ren, Guan, Kun-Liang, Shi, Ying-Hong, Yuan, Hai-Xin, Xiong, Yue

“… Phosphoenolpyruvate carboxykinase (PEPCK or PCK) catalyzes the first rate-limiting step in hepatic gluconeogenesis pathway to maintain blood glucose levels …”
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SIRT5 inhibits peroxisomal ACOX1 to prevent oxidative damage and is downregulated in liver cancer von Chen, Xiu‐Fei, Tian, Meng‐Xin, Sun, Ren‐Qiang, Zhang, Meng‐Li, Zhou, Li‐Sha, Jin, Lei, Chen, Lei‐Lei, Zhou, Wen‐Jie, Duan, Kun‐Long, Chen, Yu‐Jia, Gao, Chao, Cheng, Zhou‐Li, Wang, Fang, Zhang, Jin‐Ye, Sun, Yi‐Ping, Yu, Hong‐Xiu, Zhao, Yu‐Zheng, Yang, Yi, Liu, Wei‐Ren, Shi, Ying‐Hong, Xiong, Yue, Guan, Kun‐Liang, Ye, Dan

“… Peroxisomes account for ~35% of total H 2 O 2 generation in mammalian tissues. Peroxisomal ACOX1 (acyl‐CoA oxidase 1) is the first and rate‐limiting enzyme in …”
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Destabilization of Fatty Acid Synthase by Acetylation Inhibits De Novo Lipogenesis and Tumor Cell Growth von Lin, Huai-Peng, Cheng, Zhou-Li, He, Ruo-Yu, Song, Lei, Tian, Meng-Xin, Zhou, Li-Sha, Groh, Beezly S, Liu, Wei-Ren, Ji, Min-Biao, Ding, Chen, Shi, Ying-Hong, Guan, Kun-Liang, Ye, Dan, Xiong, Yue

“… Fatty acid synthase (FASN) is the terminal enzyme in de novo lipogenesis and plays a key role in cell proliferation. Pharmacologic inhibitors of FASN are being …”
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Design, synthesis and evaluation of diosgenin carbamate derivatives as multitarget anti-Alzheimer’s disease agents von Yang, Gui-Xiang, Huang, Yan, Zheng, Lu-Lu, Zhang, Li, Su, Lin, Wu, Yu-Hang, Li, Jie, Zhou, Li-Cheng, Huang, Jin, Tang, Yun, Wang, Rui, Ma, Lei

“… In order to produce an effective and multi-targeted clinical drug that could prevent progressive neurodegeneration, a series of diosgenin carbamate derivatives …”
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SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response von Chen, Lei-Lei, Lin, Huai-Peng, Zhou, Wen-Jie, He, Chen-Xi, Zhang, Zhi-Yong, Cheng, Zhou-Li, Song, Jun-Bin, Liu, Peng, Chen, Xin-Yu, Xia, Yu-Kun, Chen, Xiu-Fei, Sun, Ren-Qiang, Zhang, Jing-Ye, Sun, Yi-Ping, Song, Lei, Liu, Bing-Jie, Du, Rui-Kai, Ding, Chen, Lan, Fei, Huang, Sheng-Lin, Zhou, Feng, Liu, Suling, Xiong, Yue, Ye, Dan, Guan, Kun-Liang

“… The TET2 DNA dioxygenase regulates gene expression by catalyzing demethylation of 5-methylcytosine, thus epigenetically modulating the genome. TET2 does not …”
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Azvudine efficacy in reducing mortality in COVID-19 patients von Zhong, Zhen, Liu, Xiao-feng, Zhou, Xiao-zhong, Zhong, Jia-ning, Zhou, Li-cheng, Li, Rong, Liu, Xian-fa

“… Background Several therapeutic drugs have been authorized for the treatment of patients with Coronavirus disease 2019 (COVID-19). However, further research on …”
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The Zscan4-Tet2 Transcription Nexus Regulates Metabolic Rewiring and Enhances Proteostasis to Promote Reprogramming von Cheng, Zhou-Li, Zhang, Meng-Li, Lin, Huai-Peng, Gao, Chao, Song, Jun-Bin, Zheng, Zhihong, Li, Linpeng, Zhang, Yanan, Shen, Xiaoqi, Zhang, Hao, Huang, Zhenghui, Zhan, Wuqiang, Zhang, Cheng, Hu, Xu, Sun, Yi-Ping, Jiang, Lubing, Sun, Lei, Xu, Yanhui, Yang, Chen, Ge, Yuanlong, Zhao, Yong, Liu, Xingguo, Yang, Hui, Liu, Pengyuan, Guo, Xing, Guan, Kun-Liang, Xiong, Yue, Zhang, Mingliang, Ye, Dan

“… Evolutionarily conserved SCAN (named after SRE-ZBP, CTfin51, AW-1, and Number 18 cDNA)-domain-containing zinc finger transcription factors (ZSCAN) have been …”
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A comprehensive comparison on current deep learning approaches for plant image classification von Zhou, Cheng-Li, Ge, Lin-Mei, Guo, Yan-Bu, Zhou, Dong-Ming, Cun, Yu-Peng

“… Plant identification and classification play a key role in understanding, protecting and conserving biodiversity. Traditional plant taxonomy needs long time …”
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Chromium accumulation, microorganism population and enzyme activities in soils around chromium-containing slag heap of steel alloy factory von 黄顺红 彭兵 杨志辉 柴立元 周理程

“… The environmental risk of chromium pollution is pronounced in soils adjacent to chromate industry. It is important to investigate the functioning of soil …”
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Protocol for elucidating metabolite binding and regulation of TET2 dioxygenase von Zhang, Shuyuan, Cheng, Zhou-Li, Ye, Dan

“… Epigenetic enzyme activity is coupled to cellular metabolism through their reliance on metabolic cofactors and substrates. Here, we describe steps for …”
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NOTCH-induced aldehyde dehydrogenase 1A1 deacetylation promotes breast cancer stem cells von Zhao, Di, Mo, Yan, Li, Meng-Tian, Zou, Shao-Wu, Cheng, Zhou-Li, Sun, Yi-Ping, Xiong, Yue, Guan, Kun-Liang, Lei, Qun-Ying

“… High aldehyde dehydrogenase (ALDH) activity is a marker commonly used to isolate stem cells, particularly breast cancer stem cells (CSCs). Here, we determined …”
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Targeting IRG1 reverses the immunosuppressive function of tumor-associated macrophages and enhances cancer immunotherapy von Chen, Yu-Jia, Li, Guan-Nan, Li, Xian-Jing, Wei, Lin-Xing, Fu, Min-Jie, Cheng, Zhou-Li, Yang, Zhen, Zhu, Gui-Qi, Wang, Xu-Dong, Zhang, Cheng, Zhang, Jin-Ye, Sun, Yi-Ping, Saiyin, Hexige, Zhang, Jin, Liu, Wei-Ren, Zhu, Wen-Wei, Guan, Kun-Liang, Xiong, Yue, Yang, Yong, Ye, Dan, Chen, Lei-Lei

“… Immune-responsive gene 1 (IRG1) encodes aconitate decarboxylase (ACOD1) that catalyzes the production of itaconic acids (ITAs). The anti-inflammatory function …”
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Design, synthesis, and biological evaluation of diosgenin-indole derivatives as dual-functional agents for the treatment of Alzheimer’s disease von Zhou, Li-Cheng, Liang, Ying-Fan, Huang, Yi, Yang, Gui-Xiang, Zheng, Lu-Lu, Sun, Jia-Min, Li, Yang, Zhu, Fu-Li, Qian, He-Wen, Wang, Rui, Ma, Lei

“… The complex pathogenesis of Alzheimer’s disease (AD) has become a major obstacle in its treatment. An effective approach is to develop multifunctional agents …”
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Pathogen-derived glyoxylate inhibits Tet2 DNA dioxygenase to facilitate bacterial persister formation von Cheng, Zhou-Li, Zhang, Shuyuan, Wang, Zhenning, Song, Aixia, Gao, Chao, Song, Jun-Bin, Wang, Pu, Zhang, Lei, Zhou, Yue, Shan, Wenyan, Zhang, Chen, Zhang, Jinye, Sun, Yiping, Xu, Yanhui, Lan, Fei, Zhong, Ming, Lyu, Liang-Dong, Huang, Guanghua, Chen, Fei Xavier, Li, Gang, Wang, Zixin, Chen, Faying, Xue, Jianhuang, Shi, Jiejun, Liu, Yujun, Lin, Zihao, Wu, Duojiao, Na, Jim, Chen, Lei-Lei, Guan, Kun-Liang, Xiong, Yue, Ye, Dan

“… Pathogenic bacterial persistence enables survival during antibiotic treatment, leading to treatment failure and recurrent infections, yet its underlying …”
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Accelerated genetic algorithm based on search-space decomposition for change detection in remote sensing images von Mu, Cai-Hong, Li, Cheng-Zhou, Liu, Yi, Qu, Rong, Jiao, Li-Cheng

“… Detecting change areas among two or more remote sensing images is a key technique in remote sensing. It usually consists of generating and analyzing a …”
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Phototactic Behavior of Harmonia axyridis (Pallas) (Coleoptera: Coccinellidae) von Chen, Zhen, Li, Hong-Mei, Zhou, Cheng-Li

“… Harmonia axyridis (Pallas) (Coleoptera: Coccinellidae) is a well-known aphid predator in its native Asian habitat. Currently, H. axyridis are predominantly …”
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Visual and Olfactory Responses of Seven Butterfly Species During Foraging von Tang, Yu-Chong, Zhou, Cheng-Li, Chen, Xiao-Ming, Zheng, Hua

“… Foraging responses of seven butterfly species were determined for flower models that differed in color, size, and depth of artificial corolla. We measured …”
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Adult Behavior Feature of Danaus chrysippus von Tang, Yu-chong, Chen, Xiao-ming, Zhou, Cheng-li

“… [Objective]To study the behavior characteristics of the adult Danaus chrysippus. [Method]The adult butterflies D. chrysippus were observed by tracking the …”
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Impact of acetylation on tumor metabolism von Zhao, Di, Li, Fu-Long, Cheng, Zhou-Li, Lei, Qun-Ying

“… Acetylation of protein lysine residues is a reversible and dynamic process that is controlled by histone acetyltransferases (HATs) and deacetylases (HDACs and …”
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