Výsledky vyhľadávania - "Cerundolo, Lucia"

Intra-prostatic tumour evolution, steps in metastatic spread and histogenomic associations revealed by integration of multi-region whole-genome sequencing with histopathological features Autor Rao, Srinivasa, Verrill, Clare, Cerundolo, Lucia, Alham, Nasullah Khalid, Kaya, Zeynep, O’Hanlon, Miriam, Hayes, Alicia, Lambert, Adam, James, Martha, Tullis, Iain D. C., Niederer, Jane, Lovell, Shelagh, Omer, Altan, Lopez, Francisco, Leslie, Tom, Buffa, Francesca, Bryant, Richard J., Lamb, Alastair D., Vojnovic, Boris, Wedge, David C., Mills, Ian G., Woodcock, Dan J., Tomlinson, Ian, Hamdy, Freddie C.

“…Background Extension of prostate cancer beyond the primary site by local invasion or nodal metastasis is associated with poor prognosis. Despite significant…”
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Spatial transcriptomic characterization of COVID-19 pneumonitis identifies immune circuits related to tissue injury Autor Cross, Amy R., de Andrea, Carlos E., Villalba-Esparza, María, Landecho, Manuel F., Cerundolo, Lucia, Weeratunga, Praveen, Etherington, Rachel E., Denney, Laura, Ogg, Graham, Ho, Ling-Pei, Roberts, Ian S.D., Hester, Joanna, Klenerman, Paul, Melero, Ignacio, Sansom, Stephen N., Issa, Fadi

“…Severe lung damage resulting from COVID-19 involves complex interactions between diverse populations of immune and stromal cells. In this study, we used a…”
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Tumor-specific CD8 T cell characterization in HR+ breast cancer reveals an impaired antitumoral response in patients with lymph node metastasis Autor Pinho, Mariana Pereira, Antoun, Elie, Sandhar, Balraj, Shu, Ting, Gao, Fei, Yang, Xiaobao, Bates, Adam, Cerundolo, Lucia, Hamid, Megat H.B.A., Maldonado-Perez, David, Teague, Renuka, Warner, Eve, Winter, Lucinda, Alham, Nasullah Khalid, Verrill, Clare, Lord, Simon R., Rostron, Timothy, Clark, Sally-Ann, Waugh, Craig, Sopp, Paul, Conlon, Chris, Fernandes, Ricardo A., Harris, Adrian L., Peng, Yanchun, Adwani, Asha, Dong, Tao

“…Most breast cancers express the estrogen receptor (ER), but the immune response of hormone receptor-positive (HR+) breast cancer remains poorly characterized…”
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Ischemic preconditioning of cadaver donor livers protects allografts following transplantation Autor Jassem, Wayel, Fuggle, Susan V, Cerundolo, Lucia, Heaton, Nigel D, Rela, Mohamed

“…Ischemic preconditioning (IP) has been shown in animal models to protect livers against ischemia/reperfusion injury. The aim of this clinical study is to…”
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Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity Autor Hamid, Megat H. B. A., Cespedes, Pablo F., Jin, Chen, Chen, Ji-Li, Gileadi, Uzi, Antoun, Elie, Liang, Zhu, Gao, Fei, Teague, Renuka, Manoharan, Nikita, Maldonado-Perez, David, Khalid-Alham, Nasullah, Cerundolo, Lucia, Ciaoca, Raul, Hester, Svenja S., Pinto-Fernández, Adán, Draganov, Simeon D., Vendrell, Iolanda, Liu, Guihai, Yao, Xuan, Kvalvaag, Audun, Dominey-Foy, Delaney C. C., Nanayakkara, Charunya, Kanellakis, Nikolaos, Chen, Yi-Ling, Waugh, Craig, Clark, Sally-Ann, Clark, Kevin, Sopp, Paul, Rahman, Najib M., Verrill, Clare, Kessler, Benedikt M., Ogg, Graham, Fernandes, Ricardo A., Fisher, Roman, Peng, Yanchun, Dustin, Michael L., Dong, Tao

“…Cancer remains one of the leading causes of mortality worldwide, leading to increased interest in utilizing immunotherapy strategies for better cancer…”
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Self-Maintaining CD103 + Cancer-Specific T Cells Are Highly Energetic with Rapid Cytotoxic and Effector Responses Autor Abd Hamid, Megat, Colin-York, Huw, Khalid-Alham, Nasullah, Browne, Molly, Cerundolo, Lucia, Chen, Ji-Li, Yao, Xuan, Rosendo-Machado, Samara, Waugh, Craig, Maldonado-Perez, David, Bowes, Emma, Verrill, Clare, Cerundolo, Vincenzo, Conlon, Christopher P, Fritzsche, Marco, Peng, Yanchun, Dong, Tao

“…Enrichment of CD103 tumor-infiltrating T lymphocytes (TIL) is associated with improved outcomes in patients. However, the characteristics of human CD103…”
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Genomic Evolution and Transcriptional Changes in the Evolution of Prostate Cancer into Neuroendocrine and Ductal Carcinoma Types Autor Rao, Srinivasa R., Protheroe, Andrew, Cerundolo, Lucia, Maldonado-Perez, David, Browning, Lisa, Lamb, Alastair D., Bryant, Richard J., Mills, Ian G., Woodcock, Dan J., Hamdy, Freddie C., Tomlinson, Ian P. M., Verrill, Clare

“…Prostate cancer is typically of acinar adenocarcinoma type but can occasionally present as neuroendocrine and/or ductal type carcinoma. These are associated…”
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Increased EZH2 expression in prostate cancer is associated with metastatic recurrence following external beam radiotherapy Autor Wu, Xiaoning, Scott, Helen, Carlsson, Sigrid V., Sjoberg, Daniel D., Cerundolo, Lucia, Lilja, Hans, Prevo, Remko, Rieunier, Guillaume, Macaulay, Valentine, Higgins, Geoffrey S., Verrill, Clare L., Lamb, Alastair D., Cunliffe, Vincent T., Bountra, Chas, Hamdy, Freddie C., Bryant, Richard J.

“…Background Enhancer of zeste 2 (EZH2) promotes prostate cancer progression. We hypothesized that increased EZH2 expression is associated with postradiotherapy…”
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TOPK modulates tumour-specific radiosensitivity and correlates with recurrence after prostate radiotherapy Autor Pirovano, Giacomo, Ashton, Thomas M, Herbert, Katharine J, Bryant, Richard J, Verrill, Clare L, Cerundolo, Lucia, Buffa, Francesca M, Prevo, Remko, Harrap, Iona, Ryan, Anderson J, Macaulay, Valentine, McKenna, William G, Higgins, Geoff S

“…Background: Tumour-specific radiosensitising treatments may enhance the efficacy of radiotherapy without exacerbating side effects. In this study we determined…”
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Detailed Molecular and Immune Marker Profiling of Archival Prostate Cancer Samples Reveals an Inverse Association between TMPRSS2:ERG Fusion Status and Immune Cell Infiltration Autor Rao, Srinivasa R, Alham, Nasullah K, Upton, Elysia, McIntyre, Stacey, Bryant, Richard J, Cerundolo, Lucia, Bowes, Emma, Jones, Stephanie, Browne, Molly, Mills, Ian, Lamb, Alastair, Tomlinson, Ian, Wedge, David, Browning, Lisa, Sirinukunwattana, Korsuk, Palles, Claire, Hamdy, Freddie C, Rittscher, Jens, Verrill, Clare

“…Prostate cancer is a significant global health issue, and limitations to current patient management pathways often result in overtreatment or undertreatment…”
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Role of anti-vimentin antibodies in renal transplantation Autor Besarani, Dler, Cerundolo, Lucia, Smith, John D, Procter, Jeanette, Barnardo, Martin C N, Roberts, Ian S D, Friend, Peter J, Rose, Marlene L, Fuggle, Susan V

“…The role of non-HLA antibodies in rejection is not clear. We investigate whether antibodies to vimentin are made after renal transplantation and if production…”
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Altered expression of epithelial-to-mesenchymal transition proteins in extraprostatic prostate cancer Autor Verrill, Clare, Cerundolo, Lucia, Mckee, Chad, White, Michael, Kartsonaki, Christiana, Fryer, Eve, Morris, Emma, Brewster, Simon, Ratnayaka, Indrika, Marsden, Luke, Lilja, Hans, Muschel, Ruth, Lu, Xin, Hamdy, Freddie, Bryant, Richard J

“…Epithelial to mesenchymal transition (EMT) of cancer cells involves loss of epithelial polarity and adhesiveness, and gain of invasive and migratory…”
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Leukocyte infiltration and inflammatory antigen expression in cadaveric and living-donor livers before transplant Autor Jassem, Wayel, Koo, Dicken D H, Cerundolo, Lucia, Rela, Mohamed, Heaton, Nigel D, Fuggle, Susan V

“…There is evidence to indicate that organs obtained from cadaveric donors may be injured as a result of inflammatory events occurring at around the time of…”
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Cadaveric versus living-donor livers: differences in inflammatory markers after transplantation Autor Jassem, Wayel, Koo, Dicken D H, Cerundolo, Lucia, Rela, Mohamed, Heaton, Nigel D, Fuggle, Susan V

“…Prolonged cold storage of organs for transplantation may lead to inflammatory damage upon reperfusion. The aim of this study was to investigate whether organs…”
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Apoptosis in ischemia/reperfusion injury of human renal allografts Autor Burns, A T, Davies, D R, McLaren, A J, Cerundolo, L, Morris, P J, Fuggle, S V

“…Ischemia/reperfusion injury of human renal allografts has a number of clinically significant consequences. A number of mechanisms of ischemia/ reperfusion…”
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C4d deposition in early renal allograft protocol biopsies Autor Koo, Dicken D H, Roberts, Ian S D, Quiroga, Isabel, Procter, Jeanette, Barnardo, Martin C N M, Sutton, Margaret, Cerundolo, Lucia, Davies, David R, Friend, Peter J, Morris, Peter J, Fuggle, Susan V

“…Deposition of the complement protein C4d in renal allograft biopsies obtained during graft dysfunction and rejection has been proposed to be a sensitive marker…”
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Non-heart-beating versus cadaveric and living-donor livers: differences in inflammatory markers before transplantation Autor Jassem, Wayel, Koo, Dicken D H, Muiesan, Paolo, Cerundolo, Lucia, Rela, Mohamed, Fuggle, Susan V, Heaton, Nigel D

“…Liver transplantation from non-heart-beating donors (NHBD) has been reintroduced into clinical practice to increase the donor pool; however, little is known…”
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Detection of microchimerism after allogeneic blood transfusion using nested polymerase chain reaction amplification with sequence-specific primers (PCR-SSP): a cautionary tale Autor Carter, A S, Bunce, M, Cerundolo, L, Welsh, K I, Morris, P J, Fuggle, S V

“…In bone marrow transplantation, the detection of chimerism is an important adjunct to the repertoire of tests available for determining acceptance of the…”
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Nested polymerase chain reaction with sequence-specific primers typing for HLA-A, -B, and -C alleles: detection of microchimerism in DR-matched individuals Autor Carter, A S, Cerundolo, L, Bunce, M, Koo, D D, Welsh, K I, Morris, P J, Fuggle, S V

“…It is widely accepted that donor leukocytes survive within the recipient periphery after blood transfusion or solid organ transplantation. The significance of…”
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Intra-prostatic tumour evolution, steps in metastatic spread and histogenomic associations revealed by integration of multi-region whole genome sequencing with histopathological features Autor Srinivasa Rao Rao, Verrill, Clare, Cerundolo, Lucia, Nasullah Khalid Alham, Kaya, Zeynep, O'hanlon, Miriam, Hayes, Alicia, Lambert, Adam, James, Martha, Tullis, Iain D C, Niederer, Jane, Lovell, Shelagh, Altan Omer, Lopez, Francisco, Leslie, Tom, Buffa, Francesca M, Bryant, Richard John, Lamb, Alastair D, Vojnovic, Boris, Wedge, David C, Mills, Ian G, Woodcock, Dan J, Tomlinson, Ian Pm, Hamdy, Freddie C

“…Extension of prostate cancer beyond the primary site into the surrounding organs by local invasion or nodal metastasis is associated with poor prognosis. The…”
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