Výsledky vyhledávání - "Ceramides/classification"

LC/MS analysis of stratum corneum lipids: ceramide profiling and discovery Autor van Smeden, Jeroen, Hoppel, Louise, van der Heijden, Rob, Hankemeier, Thomas, Vreeken, Rob J, Bouwstra, Joke A

“…Ceramides (CERs) in the upper layer of the skin, the stratum corneum (SC), play a key role in the skin barrier function. In human SC, the literature currently…”
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Production of branched-chain very-long-chain fatty acids by fatty acid elongases and their tissue distribution in mammals Autor Tanno, Honoka, Sassa, Takayuki, Sawai, Megumi, Kihara, Akio

“…Although most mammalian fatty acids (FAs) are straight-chain, there also exist branched-chain FAs such as iso- and anteiso-FAs, especially in the meibomian…”
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Characterization of overall ceramide species in human stratum corneum Autor Masukawa, Yoshinori, Narita, Hirofumi, Shimizu, Eri, Kondo, Naoki, Sugai, Yoshiya, Oba, Tsuyoshi, Homma, Rika, Ishikawa, Junko, Takagi, Yutaka, Kitahara, Takashi, Takema, Yoshinori, Kita, Katsumi

“…Ceramides (CERs) in human stratum corneum (SC) play physicochemical roles in determining barrier and water-holding functions of the skin, and specific species…”
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Complete structural characterization of ceramides as [M−H]− ions by multiple-stage linear ion trap mass spectrometry Autor Hsu, Fong-Fu

“…Ceramide is a huge lipid family consisting of diversified structures including various modifications in the fatty acyl chain and the long chain base (LCB). In…”
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Obese Mice with Dyslipidemia Exhibit Meibomian Gland Hypertrophy and Alterations in Meibum Composition and Aqueous Tear Production Autor Osae, Eugene A., Bullock, Tiffany, Chintapalati, Madhavi, Brodesser, Susanne, Hanlon, Samuel, Redfern, Rachel, Steven, Philipp, Smith, C. Wayne, Rumbaut, Rolando E., Burns, Alan R.

“…Background: Dyslipidemia may be linked to meibomian gland dysfunction (MGD) and altered meibum lipid composition. The purpose was to determine if plasma and…”
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Human adipocyte differentiation and composition of disease-relevant lipids are regulated by miR-221-3p Autor Ahonen, Maria A., Asghar, Muhammad Yasir, Parviainen, Suvi J., Liebisch, Gerhard, Höring, Marcus, Leidenius, Marjut, Fischer-Posovszky, Pamela, Wabitsch, Martin, Mikkola, Tomi S., Törnquist, Kid, Savolainen-Peltonen, Hanna, Haridas, P.A. Nidhina, Olkkonen, Vesa M.

“…MicroRNA-221-3p (miR-221-3p) is associated with both metabolic diseases and cancers. However, its role in terminal adipocyte differentiation and lipid…”
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Ceramide subclasses identified as novel lipid biomarker elevated in women with polycystic ovary syndrome: a pilot study employing shotgun lipidomics Autor Jiang, Yihong, Qi, Jia, Xue, Xinli, Huang, Rong, Zheng, Jun, Liu, Wei, Yin, Huiyong, Li, Shengxian

“…This study aimed to identify potential lipid biomarkers in women with polycystic ovary syndrome (PCOS) and determine their predictive value for PCOS. Eighteen…”
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Consistent alteration of chain length-specific ceramides in human and mouse fibrotic kidneys Autor Eckes, Timon, Trautmann, Sandra, Djudjaj, Sonja, Beyer, Sandra, Patyna, Sammy, Schwalm, Stephanie, Gauer, Stefan, Thomas, Dominique, Schaefer, Liliana, Boor, Peter, Koch, Alexander, Pfeilschifter, Josef

“…Several studies revealed alterations of single sphingolipid species, such as chain length-specific ceramides, in plasma and serum of patients with kidney…”
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Skin Ceramide Profile in Children With Atopic Dermatitis Autor Shen, Chun-Ping, Zhao, Mu-Tong, Jia, Zhi-Xin, Zhang, Jin-Lan, Jiao, Lei, Ma, Lin

“…Atopic dermatitis (AD) is a common disease, which involves a disruption of the skin barrier function. Skin ceramide (CER) composition, which plays crucial…”
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Endogenous ligands of natural killer T cells are alpha-linked glycosylceramides Autor Kain, Lisa, Costanzo, Anne, Webb, Bill, Holt, Marie, Bendelac, Albert, Savage, Paul B., Teyton, Luc

“…•The endogenous ligands of NKT cells are α-linked monoglycosylceramides.•α-Linked monoglycosylceramides were thought to be absent from mammalian lipidomes.•New…”
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Plasma ceramides are altered in mild cognitive impairment and predict cognitive decline and hippocampal volume loss Autor Mielke, Michelle M, Haughey, Norman J, Bandaru, Veera Venkata Ratnam, Schech, Steven, Carrick, Richard, Carlson, Michelle C, Mori, Susumu, Miller, Michael I, Ceritoglu, Can, Brown, Timothy, Albert, Marilyn, Lyketsos, Constantine G

“…A blood-based biomarker of Alzheimer's disease (AD) would be superior to cerebrospinal fluid (CSF) and neuroimaging measures in terms of cost, invasiveness,…”
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The association of the lipidomic profile with features of polycystic ovary syndrome Autor Moran, L J, Mundra, P A, Teede, H J, Meikle, P J

“…Polycystic ovary syndrome (PCOS) affects up to 18% of reproductive-aged women with reproductive and metabolic complications. While lipidomics can identify…”
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Decreased Serum Levels of Sphingomyelins and Ceramides in Sickle Cell Disease Patients Autor Aslan, Mutay, Kıraç, Ebru, Kaya, Sabriye, Özcan, Filiz, Salim, Ozan, Küpesiz, Osman Alphan

“…Limited data are available on the serum levels of different sphingomyelin (CerPCho) and ceramide (CER) species in sickle‐cell disease (SCD). This study was…”
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Serum lipids profiling perturbances in patients with ischemic heart disease and ischemic cardiomyopathy Autor Yang, Lin, Wang, Liang, Deng, Yangyang, Sun, Lizhe, Lou, Bowen, Yuan, Zuyi, Wu, Yue, Zhou, Bo, Liu, Junhui, She, Jianqing

“…Background Ischemic heart disease (IHD) is a common cardiovascular disorder associated with inadequate blood supply to the myocardium. Chronic coronary…”
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Profiling of lipid species by normal-phase liquid chromatography, nanoelectrospray ionization, and ion trap–orbitrap mass spectrometry Autor Sokol, Elena, Almeida, Reinaldo, Hannibal-Bach, Hans Kristian, Kotowska, Dorota, Vogt, Johannes, Baumgart, Jan, Kristiansen, Karsten, Nitsch, Robert, Knudsen, Jens, Ejsing, Christer S.

“…Detailed analysis of lipid species can be challenging due to their structural diversity and wide concentration range in cells, tissues, and biofluids. To…”
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Nano-LC–MS/MS for the quantitation of ceramides in mice cerebrospinal fluid using minimal sample volume Autor Thomas, D., Eberle, M., Schiffmann, S., Zhang, D.D., Geisslinger, G., Ferreirós, N.

“…A new nano-liquid chromatography–ESI–MS/MS method has been developed for the sensitive quantitation of C8:0, C16:0, C18:0, C18:1, C20:0, C24:1 and C24:0…”
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Analysis of Molecular Species Profiles of Ceramide-1-phosphate and Sphingomyelin Using MALDI-TOF Mass Spectrometry Autor Yamashita, Ryouhei, Tabata, Yumika, Iga, Erina, Nakao, Michiyasu, Sano, Shigeki, Kogure, Kentaro, Tokumura, Akira, Tanaka, Tamotsu

“…Ceramide-1-phosphate (C1P) is a potential signaling molecule that modulates various cellular functions in animals. It has been known that C1P with different…”
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Comparison of rat epidermal keratinocyte organotypic culture (ROC) with intact human skin: Lipid composition and thermal phase behavior of the stratum corneum Autor Pappinen, Sari, Hermansson, Martin, Kuntsche, Judith, Somerharju, Pentti, Wertz, Philip, Urtti, Arto, Suhonen, Marjukka

“…The present report is a part of our continuing efforts to explore the utility of the rat epidermal keratinocyte organotypic culture (ROC) as an alternative…”
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Differential effects of ceramide species on exocytosis in rat PC12 cells Autor Tang, Ning, Ong, Wei-Yi, Zhang, En-Ming, Chen, Peng, Yeo, Jin-Fei

“…Increases in several ceramide species have been shown by non-targeted lipid profiling (lipidomics) of the rat hippocampus after kainate lesions (Guan et al…”
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Glycosphingolipids of porcine blood: human blood group A and H antigens with type 1 chain in erythrocytes and plasma Autor Makita, A, Gasa, S, Sako, F, Hanagata, G

“…Glycosphingolipids were purified from porcine erythrocytes and plasma. Two minor glycolipids with human blood group A and H antigenicities were found in both…”
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