Výsledky vyhledávání - "Cell death"

Intestinal IFN-γ–producing type 1 regulatory T cells coexpress CCR5 and programmed cell death protein 1 and downregulate IL-10 in the inflamed guts of patients with inflammatory bowel disease Autor Alfen, Johanna Sophie, Larghi, Paola, Facciotti, Federica, Gagliani, Nicola, Bosotti, Roberto, Paroni, Moira, Maglie, Stefano, Gruarin, Paola, Vasco, Chiara Maria, Ranzani, Valeria, Frusteri, Cristina, Iseppon, Andrea, Moro, Monica, Crosti, Maria Cristina, Gatti, Stefano, Pagani, Massimiliano, Caprioli, Flavio, Abrignani, Sergio, Flavell, Richard A., Geginat, Jens

“…+ T cells isolated from the intestinal lamina propria of human subjects and mice were analyzed for phenotype, cytokine production, and suppressive capacities…”
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Iron homeostasis and iron-regulated ROS in cell death, senescence and human diseases Autor Nakamura, Toshitaka, Naguro, Isao, Ichijo, Hidenori

“… sophisticated mechanism of cellular signalling leading to cell death and associated with various diseases…”
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Programmed cell death in aging Autor Tower, John

“…•Programmed cell death (PCD) pathways are implicated in aging and aging-related disease…”
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Incidence of Programmed Cell Death 1 Inhibitor-Related Pneumonitis in Patients With Advanced Cancer: A Systematic Review and Meta-analysis Autor Nishino, Mizuki, Giobbie-Hurder, Anita, Hatabu, Hiroto, Ramaiya, Nikhil H, Hodi, F Stephen

“…Programmed cell death 1 (PD-1) inhibitor-related pneumonitis is a rare but clinically serious and potentially life-threatening adverse event…”
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Corrigendum to “CAMSAP3-mediated regulation of HMGB1 acetylation and subcellular localization in lung cancer cells: Implications for cell death modulation”. [BBA - General Subjects (2024) 1868: 130614] Autor Singharajkomron, N., Seephan, S., Iksen, I., Chantaravisoot, N., Wongkongkathep, P., Hayakawa, Y., Pongrakhananon, V.

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Induction of ferroptosis-like cell death of eosinophils exerts synergistic effects with glucocorticoids in allergic airway inflammation Autor Wu, Yanping, Chen, Haixia, Xuan, Nanxia, Zhou, Lingren, Wu, Yinfang, Zhu, Chen, Li, Miao, Weng, Qingyu, Shen, Jiaxin, Zhang, Hao, Zhang, Bin, Lan, Fen, Xia, Lixia, Xiong, Xuefang, Li, Zhouyang, Zhao, Yun, Wu, Mindan, Ying, Songmin, Li, Wen, Shen, Huahao, Chen, Zhihua

“… Ferroptosis is a recently described novel form of cell death; however, little is known about ferroptosis in eosinophils and related diseases…”
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Programmed cell death protein‐1 (PD‐1)‐targeted immunotherapy in advanced hepatocellular carcinoma: efficacy and safety data from an international multicentre real‐world cohort Autor Scheiner, Bernhard, Kirstein, Martha M., Hucke, Florian, Finkelmeier, Fabian, Schulze, Kornelius, von Felden, Johann, Koch, Sandra, Schwabl, Philipp, Hinrichs, Jan B., Waneck, Fredrik, Waidmann, Oliver, Reiberger, Thomas, Müller, Christian, Sieghart, Wolfgang, Trauner, Michael, Weinmann, Arndt, Wege, Henning, Trojan, Jörg, Peck‐Radosavljevic, Markus, Vogel, Arndt, Pinter, Matthias

“…Summary Background Programmed cell death protein‐1‐targeted immunotherapy has shown promising results in phase II studies of hepatocellular carcinoma…”
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A role in intracellular K+ in protecting pathogenic dimorphic fungi against induced cell death by bioinspired antimicrobial peptides Autor Damica, Filipe Zaniratti, Lucas, Douglas Ribeiro, Toledo, Estefany Bras, de Carvalho Ribeiro, Marilúcia, Façanha, Anna Lvovna Okorokova, Zeraik, Ana Eliza, Seabra, Sérgio Henrique, da Silva, Juliana Azevedo, Gomes, Valdirene Moreira, de Oliveira Carvalho, André

“…Antimicrobial peptides (AMPs) are promising drugs, though their fungal combat mechanisms remain partly unclear. We designed three AMPs (dAMPs) based on the…”
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Targeting Regulated Cell Death with Pharmacological Small Molecules: An Update on Autophagy-Dependent Cell Death, Ferroptosis, and Necroptosis in Cancer Autor Wu, Junhao, Ye, Jing, Xie, Qiang, Liu, Bo, Liu, Ming

“…Regulated cell death is a widely attractive subject among the topics of cancer therapy and has gained some advances for discovery of targeted anticancer drugs…”
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High levels of FAD autofluorescence indicate pathology preceding cell death Autor Bryanskaya, Ekaterina O., Vinokurov, Andrey Y., Dolgikh, Angelina I., Dunaev, Andrey V., Angelova, Plamena R., Abramov, Andrey Y.

“…Flavin adenine dinucleotide (FAD) autofluorescence from cells reports on the enzymatic activity which involves FAD as a cofactor. Most of the cellular FAD…”
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β Cell death and dysfunction during type 1 diabetes development in at-risk individuals Autor Herold, Kevan C., Usmani-Brown, Sahar, Ghazi, Tara, Lebastchi, Jasmin, Beam, Craig A., Bellin, Melena D., Ledizet, Michel, Sosenko, Jay M., Krischer, Jeffrey P., Palmer, Jerry P.

“…; however, this primary pathologic process of the disease has not been measured. Here, we measured β cell death with an assay that detects…”
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T-cells from HLA-B57:01+ human subjects are activated with abacavir through two independent pathways and induce cell death by multiple mechanisms Autor Bell, Catherine C, Faulkner, Lee, Martinsson, Klara, Farrell, John, Alfirevic, Ana, Tugwood, Jonathan, Pirmohamed, Munir, Naisbitt, Dean J, Park, B Kevin

“…+ drug-naive subjects and to explore the relationship between abacavir accumulation in antigen presenting cells and the T-cell response. Seventy-four CD8…”
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NOD-like receptor-mediated plant immunity: from structure to cell death Autor Saur, Isabel M L, Panstruga, Ralph, Schulze-Lefert, Paul

“…) to detect pathogens, resulting in the activation of immune responses that are often associated with localized host cell death…”
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Comparison of Magnetic Resonance Imaging Features Between Programmed Cell Death 1/Programmed Cell Death Ligand 1 Inhibitor-Induced Hypopituitarism and Idiopathic Hypopituitarism in Japanese Subjects Autor Iwamoto, Yuichiro, Kimura, Tomohiko, Dan, Kazunori, Iwamoto, Hideyuki, Sanada, Junpei, Fushimi, Yoshiro, Katakura, Yukino, Shimoda, Masashi, Nakanishi, Shuhei, Mune, Tomoatsu, Kaku, Kohei, Kaneto, Hideaki

“…Objective Immune checkpoint inhibitor-associated hypopituitarism (ICI-HP) is a rare immune-related adverse event (irAE) of ICIs. This study aimed to identify…”
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Omega-3 DHA- and EPA–dopamine conjugates induce PPARγ-dependent breast cancer cell death through autophagy and apoptosis Autor Rovito, Daniela, Giordano, Cinzia, Plastina, Pierluigi, Barone, Ines, De Amicis, Francesca, Mauro, Loredana, Rizza, Pietro, Lanzino, Marilena, Catalano, Stefania, Bonofiglio, Daniela, Andò, Sebastiano

“…The omega-3 docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) may form conjugates with amines that have potential health benefits against common…”
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Cell-based measures of viral persistence are associated with immune activation and programmed cell death protein 1 (PD-1)-expressing CD4+ T cells Autor Hatano, Hiroyu, Jain, Vivek, Hunt, Peter W, Lee, Tzong-Hae, Sinclair, Elizabeth, Do, Tri D, Hoh, Rebecca, Martin, Jeffrey N, McCune, Joseph M, Hecht, Frederick, Busch, Michael P, Deeks, Steven G

“… (CD38, HLA-DR, CCR5, and/or programmed cell death…”
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Various modes of cell death induced by DNA damage Autor Surova, O, Zhivotovsky, B

“… Mild DNA damage can be repaired with or without cell-cycle arrest. More severe and irreparable DNA injury leads to the appearance of cells that carry mutations or causes a shift towards induction of the senescence or cell death programs…”
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Mitophagy-related regulated cell death: molecular mechanisms and disease implications Autor Yang, Molin, Wei, Xiang, Yi, Xin, Jiang, Ding-Sheng

“… Over the past decade, numerous studies have indicated that different forms of regulated cell death (RCD…”
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Expression of programmed cell death protein 1 and T‐cell immunoglobulin‐ and mucin‐domain‐containing molecule‐3 on peripheral blood CD4+CD8+ double positive T cells in patients with chronic hepatitis C virus infection and in subjects who spontaneously cleared the virus Autor Caraballo Cortés, Kamila, Osuch, Sylwia, Perlejewski, Karol, Pawełczyk, Agnieszka, Kaźmierczak, Justyna, Janiak, Maciej, Jabłońska, Joanna, Nazzal, Khalil, Stelmaszczyk‐Emmel, Anna, Berak, Hanna, Bukowska‐Ośko, Iwona, Paciorek, Marcin, Laskus, Tomasz, Radkowski, Marek

“… by increased expression of programmed cell death protein 1 (PD‐1) and T‐cell immunoglobulin‐ and mucin‐domain‐containing molecule‐3 (Tim‐3) on T cells. The aim of our study was to determine PD…”
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Activation-induced Cell Death Drives Profound Lung CD4 + T-Cell Depletion in HIV-associated Chronic Obstructive Pulmonary Disease Autor Popescu, Iulia, Drummond, M. Bradley, Gama, Lucio, Coon, Tiffany, Merlo, Christian A., Wise, Robert A., Clements, Janice E., Kirk, Gregory D., McDyer, John F.

“…). To determine whether individuals with HIV-associated COPD exhibit dysregulated lung mucosal T-cell immunity compared with control subjects…”
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