Suchergebnisse - "Cell cycle"

Cell-Cycle Therapeutics Come of Age von Ingham, Matthew, Schwartz, Gary K

“… The ability to sustain unscheduled proliferation is a hallmark of cancer. The normal process of cell division occurs via the cell cycle, a series of highly …”
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Cohesins and condensins orchestrate the 4D dynamics of yeast chromosomes during the cell cycle von Lazar‐Stefanita, Luciana, Scolari, Vittore F, Mercy, Guillaume, Muller, Héloise, Guérin, Thomas M, Thierry, Agnès, Mozziconacci, Julien, Koszul, Romain

“… Here, we report the first comprehensive 4D analysis of the higher‐order organization of the Saccharomyces cerevisiae genome throughout the cell cycle and investigate the roles of SMC complexes in controlling structural transitions …”
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RFC2, a direct target of miR‐744, modulates the cell cycle and promotes the proliferation of CRC cells von Hu, Tao, Shen, Hengyang, Li, Jie, Yang, Peng, Gu, Qiou, Fu, Zan

“… Colorectal cancer (CRC) is a common digestive tract malignancy, which is characterized by high mortality, morbidity, and poor prognosis. Replication factor C …”
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The TIA1 RNA-Binding Protein Family Regulates EIF2AK2-Mediated Stress Response and Cell Cycle Progression von Meyer, Cindy, Garzia, Aitor, Mazzola, Michael, Gerstberger, Stefanie, Molina, Henrik, Tuschl, Thomas

“… accumulation of aberrantly spliced mRNAs, most of which are subject to nonsense-mediated decay. Loss of PRKRA by mis-splicing triggered the activation of the double-stranded RNA …”
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Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury von Kashani, Kianoush, Al-Khafaji, Ali, Ardiles, Thomas, Artigas, Antonio, Bagshaw, Sean M, Bell, Max, Bihorac, Azra, Birkhahn, Robert, Cely, Cynthia M, Chawla, Lakhmir S, Davison, Danielle L, Feldkamp, Thorsten, Forni, Lui G, Gong, Michelle Ng, Gunnerson, Kyle J, Haase, Michael, Hackett, James, Honore, Patrick M, Hoste, Eric AJ, Joannes-Boyau, Olivier, Joannidis, Michael, Kim, Patrick, Koyner, Jay L, Laskowitz, Daniel T, Lissauer, Matthew E, Marx, Gernot, McCullough, Peter A, Mullaney, Scott, Ostermann, Marlies, Rimmelé, Thomas, Shapiro, Nathan I, Shaw, Andrew D, Shi, Jing, Sprague, Amy M, Vincent, Jean-Louis, Vinsonneau, Christophe, Wagner, Ludwig, Walker, Michael G, Wilkerson, R Gentry, Zacharowski, Kai, Kellum, John A

“… Introduction Acute kidney injury (AKI) can evolve quickly and clinical measures of function often fail to detect AKI at a time when interventions are likely to …”
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10th Anniversary of Cells-Advances in Cell Cycle

“… The Special Issue entitled “10th Anniversary of Cells—Advances in Cell Cycle” was launched together with other sister Special Issues under the umbrella …”
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Inhibitors of cell cycle checkpoint target Wee1 kinase - a patent review (2003-2022) von Yan, Jingxue, Zhuang, Lili, Wang, Yong, Jiang, Yiqing, Tu, Zhenlin, Dong, Chao, Chen, Yadong, Zhu, Yong

“… DNA damage repair in most malignancies with mutation of p53 is more dependent on the G2/M checkpoint. Wee1 kinase is a key regulator of the G2/M checkpoint. If …”
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Polystyrene microplastics mediate cell cycle arrest, apoptosis, and autophagy in the G2/M phase through ROS in grass carp kidney cells von Lu, Hongmin, Hou, Lulu, Zhang, Yue, Guo, Tiantian, Wang, Yu, Xing, Mingwei

“… However, the role of reactive oxygen species (ROS) and cell cycle in nephrotoxicity induced by different concentrations of polystyrene microplastics (PS‐MPs) is unknown …”
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Rationally designed peptide induces apoptosis and cell cycle modulation in resistant melanoma von Rocha, Layza Sá, Jacobowski, Ana Cristina, Thiburcio, Eduarda, Pereira, Rafael Araujo, Almeida, Claudiane Vilharroel, Gutierrez, Camila De Oliveira, de Andrade Farias Rodrigues, Thaís, Oliveira, Rodrigo Juliano, Taveira, Gabriel B., Hiane, Priscila Aiko, de Araújo Boleti, Ana Paula, Franco, Octávio Luiz, Cardoso, Marlon Henrique, Macedo, Maria Ligia Rodrigues

“… ). Cell cycle analysis in B16F10-Nex2 cells revealed a moderate accumulation in G0/G1 phase (62.9 …”
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TOE1 deadenylase inhibits gastric cancer cell proliferation by regulating cell cycle progression von Sun, Xiao-Lin, Song, Huan-Xi, Li, Jia-Hui, Liu, Yi-Jin, Wang, Xin-Ya, Zhang, Li-Na

“… Our recent research indicates that hCaf1a and hCaf1b isoenzymes, highly expressed in gastric cancer, promote gastric cancer cell proliferation and tumorigenicity via modulating cell cycle progression …”
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Intraoperative prediction of cardiac surgery-associated acute kidney injury using urinary biomarkers of cell cycle arrest von Cummings, Jared J, Shaw, Andrew D, Shi, Jing, Lopez, Marcos G, O'Neal, Jason B, Billings, 4th, Frederic T

“… ] between subjects who did and did not develop KDIGO stage 2 or 3 AKI within 48 hours of surgery, adjusted for AKI risk factors. Fourteen patients (3.5 …”
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Derivation and validation of cutoffs for clinical use of cell cycle arrest biomarkers von Hoste, Eric A J, McCullough, Peter A, Kashani, Kianoush, Chawla, Lakhmir S, Joannidis, Michael, Shaw, Andrew D, Feldkamp, Thorsten, Uettwiller-Geiger, Denise L, McCarthy, Paul, Shi, Jing, Walker, Michael G, Kellum, John A

“… One hundred subjects (14%) in Sapphire and 27 (18%) in Opal met the primary end point …”
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Repair of Oxidative DNA Damage, Cell-Cycle Regulation and Neuronal Death May Influence the Clinical Manifestation of Alzheimer’s Disease von Silva, Aderbal R. T., Santos, Ana Cecília Feio, Farfel, Jose M., Grinberg, Lea T., Ferretti, Renata E. L., Campos, Antonio Hugo Jose Froes Marques, Cunha, Isabela Werneck, Begnami, Maria Dirlei, Rocha, Rafael M., Carraro, Dirce M., de Bragança Pereira, Carlos Alberto, Jacob-Filho, Wilson, Brentani, Helena

“… (neuritic plaques and neurofibrillary tangles). Several studies have implicated oxidative damage to DNA, DNA repair, and altered cell-cycle regulation in addition to cell death in AD post-mitotic neurons …”
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Integrating DNA damage repair with the cell cycle von Murray, Johanne M, Carr, Antony M

“… Cell duplication is orchestrated by the cell division cycle and specific DNA structures are processed differently depending on where in the cell cycle they are detected …”
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Cell cycle entry, maintenance, and exit during plant development von Polyn, Stefanie, Willems, Alex, De Veylder, Lieven

“… Although over the past decades the molecular components underlying cell cycle progression have been the subject of intensive research, knowledge remains scarce on how the various elements connect …”
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DNA Repair and Cell Cycle Biomarkers of Radiation Exposure and Inflammation Stress in Human Blood von Budworth, Helen, Snijders, Antoine M., Marchetti, Francesco, Mannion, Brandon, Bhatnagar, Sandhya, Kwoh, Ely, Tan, Yuande, Wang, Shan X., Blakely, William F., Coleman, Matthew, Peterson, Leif, Wyrobek, Andrew J.

“… DNA damage and repair are hallmarks of cellular responses to ionizing radiation. We hypothesized that monitoring the expression of DNA repair-associated genes …”
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Progenitors in the adult cerebral cortex: Cell cycle properties and regulation by physiological stimuli and injury von Simon, Christiane, Götz, Magdalena, Dimou, Leda

“… Here, we first characterized the cell cycle length, proliferative fraction, and progeny of dividing cells in the adult cerebral cortex and then compared these proliferation characteristics after two …”
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G9a and DNMT1 inhibition modulates CDKN1A promoter methylation and the cell cycle leading to improvement in kidney fibrosis von Yang, Yuanyuan, Zhou, Zijian, Wang, Lujia, Gao, Peng, Wu, Zhong

“… Antifibrogenic activity and safety of CM272 were studied in UUO mouse. Cell cycle were analyzed with flow cytometry …”
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Hunting the Cell Cycle Snark von Norris, Vic

“… In this very personal hunt for the meaning of the bacterial cell cycle, the snark, I briefly revisit and update some of the mechanisms we and many others have proposed to regulate the bacterial cell cycle …”
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Exosomes from patients with septic shock convey miRNAs related to inflammation and cell cycle regulation: new signaling pathways in sepsis? von Real, Juliana Monte, Ferreira, Ludmila Rodrigues Pinto, Esteves, Gustavo Henrique, Koyama, Fernanda Christtanini, Dias, Marcos Vinícius Salles, Bezerra-Neto, João Evangelista, Cunha-Neto, Edécio, Machado, Flavia Ribeiro, Salomão, Reinaldo, Azevedo, Luciano Cesar Pontes

“… Twelve healthy volunteers were used as control subjects. Exosomes were isolated by ultracentrifugation, and their miRNA …”
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