Search Results - "Cell Nucleus - metabolism"

Nesprin-2G, a Component of the Nuclear LINC Complex, Is Subject to Myosin-Dependent Tension by Arsenovic, Paul T, Ramachandran, Iswarya, Bathula, Kranthidhar, Zhu, Ruijun, Narang, Jiten D, Noll, Natalie A, Lemmon, Christopher A, Gundersen, Gregg G, Conway, Daniel E

“…The nucleus of a cell has long been considered to be subject to mechanical force…”
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Catalase: A critical node in the regulation of cell fate by Baker, Alison, Lin, Chi-Chuan, Lett, Casey, Karpinska, Barbara, Wright, Megan H., Foyer, Christine H.

“… CAT proteins are subject to many types of post-translational modification (PTM), which modify activity, ligand binding, stability, compartmentation and function…”
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Exploring the cell nucleus: From chromosome structure to single-cell omics by Fukagawa, Tatsuo, Torres-Padilla, Maria Elena

“…The cell nucleus is a fascinating organelle. The myriad of fundamental processes that ensure that the genetic information is read correctly and faithfully transmitted provides a rich subject of research across time scales and model systems…”
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RNAi Factors Are Present and Active in Human Cell Nuclei by Gagnon, Keith T., Li, Liande, Chu, Yongjun, Janowski, Bethany A., Corey, David R.

“… However, the presence and activity of RNAi factors in the mammalian nucleus has been the subject of considerable debate…”
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Quantitative subcellular acyl-CoA analysis reveals distinct nuclear metabolism and isoleucine-dependent histone propionylation by Trefely, Sophie, Huber, Katharina, Liu, Joyce, Noji, Michael, Stransky, Stephanie, Singh, Jay, Doan, Mary T, Lovell, Claudia D, von Krusenstiern, Eliana, Jiang, Helen, Bostwick, Anna, Pepper, Hannah L, Izzo, Luke, Zhao, Steven, Xu, Jimmy P, Bedi, Jr, Kenneth C, Rame, J Eduardo, Bogner-Strauss, Juliane G, Mesaros, Clementina, Sidoli, Simone, Wellen, Kathryn E, Snyder, Nathaniel W

“…Quantitative subcellular metabolomic measurements can explain the roles of metabolites in cellular processes but are subject to multiple confounding factors…”
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RNA localization: Making its way to the center stage by Chin, Ashley, Lécuyer, Eric

“…Cells are highly organized entities that rely on intricate addressing mechanisms to sort their constituent molecules to precise subcellular locations. These…”
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A nuclear F-actin scaffold stabilizes ribonucleoprotein droplets against gravity in large cells by Feric, Marina, Brangwynne, Clifford P.

“…Actin is abundant in the nuclei of oocytes but its role has been unclear. Feric and Brangwynne find that actin forms a network that prevents the sedimentation…”
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Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis by Haak, Andrew J, Kostallari, Enis, Sicard, Delphine, Ligresti, Giovanni, Choi, Kyoung Moo, Caporarello, Nunzia, Jones, Dakota L, Tan, Qi, Meridew, Jeffrey, Diaz Espinosa, Ana M, Aravamudhan, Aja, Maiers, Jessica L, Britt, Jr, Rodney D, Roden, Anja C, Pabelick, Christina M, Prakash, Y S, Nouraie, Seyed Mehdi, Li, Xiaoyun, Zhang, Yingze, Kass, Daniel J, Lagares, David, Tager, Andrew M, Varelas, Xaralabos, Shah, Vijay H, Tschumperlin, Daniel J

“…Tissue fibrosis is characterized by uncontrolled deposition and diminished clearance of fibrous connective tissue proteins, ultimately leading to organ…”
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Structure-Function Analysis of SMAX1 Reveals Domains That Mediate Its Karrikin-Induced Proteolysis and Interaction with the Receptor KAI2 by Khosla, Aashima, Morffy, Nicholas, Li, Qingtian, Faure, Lionel, Chang, Sun Hyun, Yao, Jiaren, Zheng, Jiameng, Cai, Mei L, Stanga, John, Flematti, Gavin R, Waters, Mark T, Nelson, David C

“…Karrikins (KARs) are butenolides found in smoke that can influence germination and seedling development of many plants. The KAR signaling mechanism is…”
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Identification of epilepsy-associated neuronal subtypes and gene expression underlying epileptogenesis by Pfisterer, Ulrich, Petukhov, Viktor, Demharter, Samuel, Meichsner, Johanna, Thompson, Jonatan J., Batiuk, Mykhailo Y., Asenjo-Martinez, Andrea, Vasistha, Navneet A., Thakur, Ashish, Mikkelsen, Jens, Adorjan, Istvan, Pinborg, Lars H., Pers, Tune H., von Engelhardt, Jakob, Kharchenko, Peter V., Khodosevich, Konstantin

“… of >110,000 neuronal transcriptomes derived from temporal cortex samples of multiple temporal lobe epilepsy and non-epileptic subjects…”
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Alterations in the chromatin packaging, driven by transcriptional activity, revealed by AFM by Bairamukov, V. Yu, Kovalev, R.A., Ankudinov, A.V., Pantina, R.A., Fedorova, N.D., Bukatin, A.S., Grigoriev, S.V., Varfolomeeva, E. Yu

“…The gene expression differs in the nuclei of normal and malignant mammalian cells, and transcription is a critical initial step, which defines the difference…”
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SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity by Yao, Fan, Zhou, Zhicheng, Kim, Jongchan, Hang, Qinglei, Xiao, Zhenna, Ton, Baochau N., Chang, Liang, Liu, Na, Zeng, Liyong, Wang, Wenqi, Wang, Yumeng, Zhang, Peijing, Hu, Xiaoyu, Su, Xiaohua, Liang, Han, Sun, Yutong, Ma, Li

“… Here, we report that YAP is subject to non-proteolytic, K63-linked polyubiquitination by the SCF SKP2 E3 ligase complex (SKP2…”
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Histone acetyltransferase MoHat1 acetylates autophagy-related proteins MoAtg3 and MoAtg9 to orchestrate functional appressorium formation and pathogenicity in Magnaporthe oryzae by Yin, Ziyi, Chen, Chen, Yang, Jie, Feng, Wanzhen, Liu, Xinyu, Zuo, Rongfang, Wang, Jingzhen, Yang, Lina, Zhong, Kaili, Gao, Chuyun, Zhang, Haifeng, Zheng, Xiaobo, Wang, Ping, Zhang, Zhengguang

“… We also found that MoHat1 was subject to regulation by the protein kinase MoGsk1 that modulated the translocation of MoHat1 from the nucleus to the cytoplasm with the assistance of MoSsb1, a protein chaperone…”
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The molecular mechanism and functional diversity of UPR signaling sensor IRE1 by Bashir, Samirul, Banday, Mariam, Qadri, Ozaira, Bashir, Arif, Hilal, Nazia, Nida-i-Fatima, Rader, Stephen, Fazili, Khalid Majid

“… However, the organelle is subject to varied stress conditions from time to time, which lead to the activation of a signaling program known as the Unfolded Protein Response (UPR) pathway…”
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Tension and Resolution: Dynamic, Evolving Populations of Organelle Genomes within Plant Cells by Johnston, Iain G.

“…Mitochondria and plastids form dynamic, evolving populations physically embedded in the fluctuating environment of the plant cell. Their evolutionary heritage…”
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The membrane-bound NAC transcription factor ANAC013 functions in mitochondrial retrograde regulation of the oxidative stress response in Arabidopsis by De Clercq, Inge, Vermeirssen, Vanessa, Van Aken, Olivier, Vandepoele, Klaas, Murcha, Monika W, Law, Simon R, Inzé, Annelies, Ng, Sophia, Ivanova, Aneta, Rombaut, Debbie, van de Cotte, Brigitte, Jaspers, Pinja, Van de Peer, Yves, Kangasjärvi, Jaakko, Whelan, James, Van Breusegem, Frank

“…Upon disturbance of their function by stress, mitochondria can signal to the nucleus to steer the expression of responsive genes. This mitochondria-to-nucleus…”
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Mechanical confinement triggers spreading and migration of immobile cells by deforming nucleus by Rao, Ran, Yang, Haoxiang, Qiu, Kailong, Xu, Min, Liu, Hao, Shen, Jinghao, Wang, Weihao, Nie, Runjie, Chen, Huan, Jiang, Hongyuan

“…Cells in vivo are often subject to the challenge of spatial confinement from neighboring cells and extracellular matrix (ECM…”
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Chromatin hydrodynamics by Bruinsma, Robijn, Grosberg, Alexander Y, Rabin, Yitzhak, Zidovska, Alexandra

“… solute. This system is subject to both passive thermal fluctuations and active scalar and vector events that are associated with free energy consumption, such as ATP hydrolysis…”
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Nuclear lamins are not required for lamina-associated domain organization in mouse embryonic stem cells by Amendola, Mario, van Steensel, Bas

“…In mammals, the nuclear lamina interacts with hundreds of large genomic regions, termed lamina‐associated domains (LADs) that are generally in a…”
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NIK1-mediated translation suppression functions as a plant antiviral immunity mechanism by Zorzatto, Cristiane, Machado, João Paulo B., Lopes, Kênia V. G., Nascimento, Kelly J. T., Pereira, Welison A., Brustolini, Otávio J. B., Reis, Pedro A. B., Calil, Iara P., Deguchi, Michihito, Sachetto-Martins, Gilberto, Gouveia, Bianca C., Loriato, Virgílio A. P., Silva, Marcos A. C., Silva, Fabyano F., Santos, Anésia A., Chory, Joanne, Fontes, Elizabeth P. B.

“…A new mechanism that plants use to combat begomoviruses—one of the most pathogenic groups of plant viruses, causing severe disease in major crops worldwide—is…”
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