Search Results - "Cell Adhesion"

Elevated Expression of Serum Endothelial Cell Adhesion Molecules in COVID-19 Patients by Tong, Ming, Jiang, Yu, Xia, Da, Xiong, Ying, Zheng, Qing, Chen, Fang, Zou, Lianhong, Xiao, Wen, Zhu, Yimin

“…In a retrospective study of 39 COVID-19 patients and 32 control participants in China, we collected clinical data and examined the expression of endothelial…”
Get more information

Expression and function of epithelial cell adhesion molecule EpCAM: where are we after 40 years? by Gires, Olivier, Pan, Min, Schinke, Henrik, Canis, Martin, Baeuerle, Patrick A.

“…EpCAM (epithelial cell adhesion molecule) was discovered four decades ago as a tumor antigen on colorectal carcinomas. Owing to its frequent and high…”
Get full text

Heparan Sulfate Organizes Neuronal Synapses through Neurexin Partnerships by Zhang, Peng, Lu, Hong, Peixoto, Rui T, Pines, Mary K, Ge, Yuan, Oku, Shinichiro, Siddiqui, Tabrez J, Xie, Yicheng, Wu, Wenlan, Archer-Hartmann, Stephanie, Yoshida, Keitaro, Tanaka, Kenji F, Aricescu, A Radu, Azadi, Parastoo, Gordon, Michael D, Sabatini, Bernardo L, Wong, Rachel O L, Craig, Ann Marie

“…Synapses are fundamental units of communication in the brain. The prototypical synapse-organizing complex neurexin-neuroligin mediates synapse development and…”
Get more information

Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1 by Yousef, Hanadie, Czupalla, Cathrin J, Lee, Davis, Chen, Michelle B, Burke, Ashley N, Zera, Kristy A, Zandstra, Judith, Berber, Elisabeth, Lehallier, Benoit, Mathur, Vidhu, Nair, Ramesh V, Bonanno, Liana N, Yang, Andrew C, Peterson, Todd, Hadeiba, Husein, Merkel, Taylor, Körbelin, Jakob, Schwaninger, Markus, Buckwalter, Marion S, Quake, Stephen R, Butcher, Eugene C, Wyss-Coray, Tony

“…An aged circulatory environment can activate microglia, reduce neural precursor cell activity and impair cognition in mice. We hypothesized that brain…”
Get full text

An EpCAM/Trop2 mechanostat differentially regulates collective behaviour of human carcinoma cells by Aslemarz, Azam, Fagotto-Kaufmann, Marie, Ruppel, Artur, Fagotto-Kaufmann, Christine, Balland, Martial, Lasko, Paul, Fagotto, François

“…EpCAM and its close relative Trop2 are well-known cell surface markers of carcinoma, but their potential role in cancer metastasis remains unclear. They are…”
Get full text

Light-triggered in vivo activation of adhesive peptides regulates cell adhesion, inflammation and vascularization of biomaterials by Lee, Ted T., García, José R., Paez, Julieta I., Singh, Ankur, Phelps, Edward A., Weis, Simone, Shafiq, Zahid, Shekaran, Asha, del Campo, Aránzazu, García, Andrés J.

“…Materials engineered to elicit targeted cellular responses in regenerative medicine must display bioligands with precise spatial and temporal control. Although…”
Get full text

The role of nectins in different types of cell-cell adhesion by Rikitake, Yoshiyuki, Mandai, Kenji, Takai, Yoshimi

“…Mammalian tissues and organs are composed of different types of cells that adhere to each other homotypically (i.e. interactions between cells of the same cell…”
Get more information

Coordinated internodal and paranodal adhesion controls accurate myelination by oligodendrocytes by Elazar, Nimrod, Vainshtein, Anya, Rechav, Katya, Tsoory, Michael, Eshed-Eisenbach, Yael, Peles, Elior

“…Oligodendrocyte-axon contact is mediated by several cell adhesion molecules (CAMs) that are positioned at distinct sites along the myelin unit, yet their role…”
Get more information

Fascinating Fasciclins: A Surprisingly Widespread Family of Proteins that Mediate Interactions between the Cell Exterior and the Cell Surface by Seifert, Georg J.

“…The Fasciclin 1 (FAS1) domain is an ancient structural motif in extracellular proteins present in all kingdoms of life and particularly abundant in plants. The…”
Get full text

Lipid-induced endothelial vascular cell adhesion molecule 1 promotes nonalcoholic steatohepatitis pathogenesis by Furuta, Kunimaro, Guo, Qianqian, Pavelko, Kevin D., Lee, Jeong-Heon, Robertson, Keith D., Nakao, Yasuhiko, Melek, Jan, Shah, Vijay H., Hirsova, Petra, Ibrahim, Samar H.

“…Monocyte homing to the liver and adhesion to the liver sinusoidal endothelial cells (LSECs) are key elements in nonalcoholic steatohepatitis (NASH)…”
Get full text

The neurexin ligands, neuroligins and leucine-rich repeat transmembrane proteins, perform convergent and divergent synaptic functions in vivo by Soler-Llavina, Gilberto J, Fuccillo, Marc V, Ko, Jaewon, Südhof, Thomas C, Malenka, Robert C

“…Synaptic cell adhesion molecules, including the neurexin ligands, neuroligins (NLs) and leucine-rich repeat transmembrane proteins (LRRTMs), are thought to…”
Get more information

Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization by Er, Ekrem Emrah, Valiente, Manuel, Ganesh, Karuna, Zou, Yilong, Agrawal, Saloni, Hu, Jing, Griscom, Bailey, Rosenblum, Marc, Boire, Adrienne, Brogi, Edi, Giancotti, Filippo G., Schachner, Melitta, Malladi, Srinivas, Massagué, Joan

“…Metastatic seeding by disseminated cancer cells principally occurs in perivascular niches. Here, we show that mechanotransduction signalling triggered by the…”
Get full text

Serum EpCAM or PECAM Levels and Risk of Ischemic Stroke: A Two-Sample Mendelian Randomization Study by Yikun, Gao, Yilin, Li, Yina, Li, Jin, Wang, Qiang, Cai, Lijuan, Gu

“…Elevated serum Epithelial cell adhesion molecule (EpCAM) or Platelet endothelial cell adhesion molecule (PECAM) are associated with ischemic stroke (IS), but…”
Get full text

Programming multicellular assembly with synthetic cell adhesion molecules by Stevens, Adam J., Harris, Andrew R., Gerdts, Josiah, Kim, Ki H., Trentesaux, Coralie, Ramirez, Jonathan T., McKeithan, Wesley L., Fattahi, Faranak, Klein, Ophir D., Fletcher, Daniel A., Lim, Wendell A.

“…Cell adhesion molecules are ubiquitous in multicellular organisms, specifying precise cell–cell interactions in processes as diverse as tissue development,…”
Get full text

Reelin controls neuronal positioning by promoting cell-matrix adhesion via inside-out activation of integrin α5β1 by Sekine, Katsutoshi, Kawauchi, Takeshi, Kubo, Ken-Ichiro, Honda, Takao, Herz, Joachim, Hattori, Mitsuharu, Kinashi, Tatsuo, Nakajima, Kazunori

“…Birthdate-dependent neuronal layering is fundamental to neocortical functions. The extracellular protein Reelin is essential for the establishment of the…”
Get more information

Functions of EpCAM in physiological processes and diseases (Review) by Huang, Li, Yang, Yanhong, Yang, Fei, Liu, Shaomin, Zhu, Ziqin, Lei, Zili, Guo, Jiao

“…EpCAM (epithelial cell adhesion molecule) is a type I transmembrane glycoprotein, which was originally identified as a tumor-associated antigen due to its high…”
Get full text

Junctional adhesion molecule-C: A multifunctional mediator of cell adhesion by Ebnet, Klaus, Aurrand-Lions, Michel

“…Junctional Adhesion Molecule-C (JAM-C) is a member of the JAM family of cell adhesion molecules. JAM-C is expressed by a large variety of tissues including…”
Get full text

Chemico-genetic discovery of astrocytic control of inhibition in vivo by Takano, Tetsuya, Wallace, John T., Baldwin, Katherine T., Purkey, Alicia M., Uezu, Akiyoshi, Courtland, Jamie L., Soderblom, Erik J., Shimogori, Tomomi, Maness, Patricia F., Eroglu, Cagla, Soderling, Scott H.

“…Perisynaptic astrocytic processes are an integral part of central nervous system synapses 1 , 2 ; however, the molecular mechanisms that govern…”
Get full text

Nitric Oxide Inhibits Hetero-adhesion of Cancer Cells to Endothelial Cells: Restraining Circulating Tumor Cells from Initiating Metastatic Cascade by Lu, Yusheng, Yu, Ting, Liang, Haiyan, Wang, Jichuang, Xie, Jingjing, Shao, Jingwei, Gao, Yu, Yu, Suhong, Chen, Shuming, Wang, Lie, Jia, Lee

“…Adhesion of circulating tumor cells (CTCs) to vascular endothelial bed becomes a crucial starting point in metastatic cascade. We hypothesized that nitric…”
Get full text

Quantitatively Mapping the Assembly Pattern of EpCAM on Cell Membranes with Peptide Probes by Jing, Yingying, Zhou, Lulu, Chen, Junling, Xu, Haijiao, Sun, Jiayin, Cai, Mingjun, Jiang, Junguang, Gao, Jing, Wang, Hongda

“…Epithelial cell adhesion molecule (EpCAM) is an important type I transmembrane protein that is overexpressed on the surfaces of most cancer cells and involved…”
Get more information