Suchergebnisse - "Cartwright, Emily K"

CD8(+) Lymphocytes Are Required for Maintaining Viral Suppression in SIV-Infected Macaques Treated with Short-Term Antiretroviral Therapy von Cartwright, Emily K, Spicer, Lori, Smith, S Abigail, Lee, David, Fast, Randy, Paganini, Sara, Lawson, Benton O, Nega, Melon, Easley, Kirk, Schmitz, Joern E, Bosinger, Steven E, Paiardini, Mirko, Chahroudi, Ann, Vanderford, Thomas H, Estes, Jacob D, Lifson, Jeffrey D, Derdeyn, Cynthia A, Silvestri, Guido

“… Infection with HIV persists despite suppressive antiretroviral therapy (ART), and treatment interruption results in rapid viral rebound. Antibody-mediated …”
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CD8+ lymphocyte control of SIV infection during antiretroviral therapy von Cao, Youfang, Cartwright, Emily K., Silvestri, Guido, Perelson, Alan S.

“… CD8+ lymphocytes play an important role in suppressing in vivo viral replication in HIV infection. However, both the extent to which and the mechanisms by …”
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CAR/CXCR5-T cell immunotherapy is safe and potentially efficacious in promoting sustained remission of SIV infection von Pampusch, Mary S., Abdelaal, Hadia M., Cartwright, Emily K., Molden, Jhomary S., Davey, Brianna C., Sauve, Jordan D., Sevcik, Emily N., Rendahl, Aaron K., Rakasz, Eva G., Connick, Elizabeth, Berger, Edward A., Skinner, Pamela J.

“… During chronic human immunodeficiency virus (HIV) or simian immunodeficiency virus (SIV) infection prior to AIDS progression, the vast majority of viral …”
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Development of an anti-CAR antibody response in SIV-infected rhesus macaques treated with CD4-MBL CAR/CXCR5 T cells von Davey, Brianna C., Pampusch, Mary S., Cartwright, Emily K., Abdelaal, Hadia M., Rakasz, Eva G., Rendahl, Aaron, Berger, Edward A., Skinner, Pamela J.

“… T cells expressing a simian immunodeficiency (SIV)-specific chimeric antigen receptor (CAR) and the follicular homing molecule, CXCR5, were infused into …”
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CXCR6 regulates localization of tissue-resident memory CD8 T cells to the airways von Wein, Alexander N, McMaster, Sean R, Takamura, Shiki, Dunbar, Paul R, Cartwright, Emily K, Hayward, Sarah L, McManus, Daniel T, Shimaoka, Takeshi, Ueha, Satoshi, Tsukui, Tatsuya, Masumoto, Tomoko, Kurachi, Makoto, Matsushima, Kouji, Kohlmeier, Jacob E

“… Resident memory T cells (T cells) are an important first-line defense against respiratory pathogens, but the unique contributions of lung T cell populations to …”
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Environmental cues regulate epigenetic reprogramming of airway-resident memory CD8+ T cells von Hayward, Sarah L., Scharer, Christopher D., Cartwright, Emily K., Takamura, Shiki, Li, Zheng-Rong Tiger, Boss, Jeremy M., Kohlmeier, Jacob E.

“… Tissue-resident memory T cells (T RM cells) are critical for cellular immunity to respiratory pathogens and reside in both the airways and the interstitium. In …”
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Long-term maintenance of lung resident memory T cells is mediated by persistent antigen von Uddbäck, Ida, Cartwright, Emily K., Schøller, Amalie S., Wein, Alexander N., Hayward, Sarah L., Lobby, Jenna, Takamura, Shiki, Thomsen, Allan R., Kohlmeier, Jacob E., Christensen, Jan P.

“… Tissue-resident memory T cells (TRM) in the lungs are pivotal for protection against repeated infection with respiratory viruses. However, the gradual loss of …”
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Pulmonary antigen encounter regulates the establishment of tissue-resident CD8 memory T cells in the lung airways and parenchyma von McMaster, Sean R., Wein, Alexander N., Dunbar, Paul R., Hayward, Sarah L., Cartwright, Emily K., Denning, Timothy L., Kohlmeier, Jacob E.

“… Resident memory CD8 T (TRM) cells in the lung parenchyma (LP) and airways provide heterologous protection against influenza virus challenge. However, scant …”
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Detection of Antigen-Specific T Cells Using In Situ MHC Tetramer Staining von Abdelaal, Hadia M., Cartwright, Emily K., Skinner, Pamela J.

“… The development of in situ major histocompatibility complex (MHC) tetramer (IST) staining to detect antigen (Ag)-specific T cells in tissues has radically …”
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Initiation of Antiretroviral Therapy Restores CD4+ T Memory Stem Cell Homeostasis in Simian Immunodeficiency Virus-Infected Macaques von Cartwright, Emily K, Palesch, David, Mavigner, Maud, Paiardini, Mirko, Chahroudi, Ann, Silvestri, Guido

“… Treatment of human immunodeficiency virus (HIV) infection with antiretroviral therapy (ART) has significantly improved prognosis. Unfortunately, interruption …”
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Pulmonary monocytes interact with effector T cells in the lung tissue to drive TRM differentiation following viral infection von Dunbar, Paul R., Cartwright, Emily K., Wein, Alexander N., Tsukamoto, Tetsuo, Tiger Li, Zheng-Rong, Kumar, Nivedha, Uddbäck, Ida E., Hayward, Sarah L., Ueha, Satoshi, Takamura, Shiki, Kohlmeier, Jacob E.

“… Lung resident memory CD8 T cells (TRM) are critical for protection against respiratory viruses, but the cellular interactions required for their development …”
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Pulmonary monocytes interact with effector T cells in the lung tissue to drive T RM differentiation following viral infection von Dunbar, Paul R, Cartwright, Emily K, Wein, Alexander N, Tsukamoto, Tetsuo, Tiger Li, Zheng-Rong, Kumar, Nivedha, Uddbäck, Ida E, Hayward, Sarah L, Ueha, Satoshi, Takamura, Shiki, Kohlmeier, Jacob E

“… Lung resident memory CD8 T cells (T ) are critical for protection against respiratory viruses, but the cellular interactions required for their development are …”
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Divergent CD4+ T memory stem cell dynamics in pathogenic and nonpathogenic simian immunodeficiency virus infections von Cartwright, Emily K, McGary, Colleen S, Cervasi, Barbara, Micci, Luca, Lawson, Benton, Elliott, Sarah T C, Collman, Ronald G, Bosinger, Steven E, Paiardini, Mirko, Vanderford, Thomas H, Chahroudi, Ann, Silvestri, Guido

“… Recent studies have identified a subset of memory T cells with stem cell-like properties (T(SCM)) that include increased longevity and proliferative potential …”
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HIV-Specific CAR T Cells with CD28 or 4-1BB Signaling Domains Are Phenotypically and Functionally Distinct and Effective at Suppressing HIV and Simian Immunodeficiency Virus von Cartwright, Emily K, Pampusch, Mary S, Rendahl, Aaron K, Berger, Edward A, Coleman-Fuller, Natalie, Skinner, Pamela J

“… Despite mounting a robust antiviral CD8 T cell response to HIV infection, most infected individuals are unable to control HIV viral load without antiretroviral …”
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Plasmacytoid Dendritic Cell Infection and Sensing Capacity during Pathogenic and Nonpathogenic Simian Immunodeficiency Virus Infection von Jochems, Simon P, Jacquelin, Beatrice, Chauveau, Lise, Huot, Nicolas, Petitjean, Gaël, Lepelley, Alice, Liovat, Anne-Sophie, Ploquin, Mickaël J, Cartwright, Emily K, Bosinger, Steven E, Silvestri, Guido, Barré-Sinoussi, Françoise, Lebon, Pierre, Schwartz, Olivier, Müller-Trutwin, Michaela C

“… Human immunodeficiency virus (HIV) in humans and simian immunodeficiency virus (SIV) in macaques (MAC) lead to chronic inflammation and AIDS. Natural hosts, …”
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Environmental cues regulate epigenetic reprogramming of airway-resident memory CD8.sup.+ T cells von Hayward, Sarah L, Scharer, Christopher D, Cartwright, Emily K, Takamura, Shiki, Li, Zheng-Rong Tiger, Boss, Jeremy M, Kohlmeier, Jacob E

“… Tissue-resident memory T cells (T.sub.RM cells) are critical for cellular immunity to respiratory pathogens and reside in both the airways and the …”
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CAR/CXCR5-T cell immunotherapy is safe and potentially efficacious in promoting sustained remission of SIV infection von Pampusch, Mary S, Abdelaal, Hadia M, Cartwright, Emily K, Molden, Jhomary S, Davey, Brianna C, Sauve, Jordan D, Rendahl, Aaron K, Rakasz, Eva G, Connick, Elizabeth, Berger, Edward A, Skinner, Pamela J

“… During chronic human immunodeficiency virus (HIV) or simian immunodeficiency virus (SIV) infection prior to AIDS progression, the vast majority of viral …”
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