Suchergebnisse - "Carcinoma, Hepatocellular blood"

Ramucirumab after sorafenib in patients with advanced hepatocellular carcinoma and increased α-fetoprotein concentrations (REACH-2): a randomised, double-blind, placebo-controlled, phase 3 trial von Zhu, Andrew X, Kang, Yoon-Koo, Yen, Chia-Jui, Finn, Richard S, Galle, Peter R, Llovet, Josep M, Assenat, Eric, Brandi, Giovanni, Pracht, Marc, Lim, Ho Yeong, Rau, Kun-Ming, Motomura, Kenta, Ohno, Izumi, Merle, Philippe, Daniele, Bruno, Shin, Dong Bok, Gerken, Guido, Borg, Christophe, Hiriart, Jean-Baptiste, Okusaka, Takuji, Morimoto, Manabu, Hsu, Yanzhi, Abada, Paolo B, Kudo, Masatoshi

“… Patients with advanced hepatocellular carcinoma and increased α-fetoprotein concentrations have poor prognosis. We aimed to establish the efficacy of …”
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Detection of Circulating Tumor Cells and Their Implications as a Biomarker for Diagnosis, Prognostication, and Therapeutic Monitoring in Hepatocellular Carcinoma von Ahn, Joseph C., Teng, Pai‐Chi, Chen, Pin‐Jung, Posadas, Edwin, Tseng, Hsian‐Rong, Lu, Shelly C., Yang, Ju Dong

“… Hepatocellular carcinoma (HCC) is among the leading causes of worldwide cancer‐related morbidity and mortality. Poor prognosis of HCC is attributed primarily …”
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Prognostic role of plasma level of angiopoietin-1, angiopoietin-2, and vascular endothelial growth factor in hepatocellular carcinoma von Choi, Gwang Hyeon, Jang, Eun Sun, Kim, Jin-Wook, Jeong, Sook-Hyang

“… Most hepatocellular carcinomas (HCCs) are hypervascular, with characteristic features of hepatic arterial supply to the tumor. The factors involved in tumor …”
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Biology and significance of alpha‐fetoprotein in hepatocellular carcinoma von Galle, Peter R., Foerster, Friedrich, Kudo, Masatoshi, Chan, Stephen L., Llovet, Josep M., Qin, Shukui, Schelman, William R., Chintharlapalli, Sudhakar, Abada, Paolo B., Sherman, Morris, Zhu, Andrew X.

“… Hepatocellular carcinoma (HCC) is one of the most common causes of cancer‐related deaths globally due, in part, to the majority of patients being diagnosed …”
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Metroticket 2.0 Model for Analysis of Competing Risks of Death After Liver Transplantation for Hepatocellular Carcinoma von Mazzaferro, Vincenzo, Sposito, Carlo, Zhou, Jian, Pinna, Antonio D, De Carlis, Luciano, Fan, Jia, Cescon, Matteo, Di Sandro, Stefano, Yi-Feng, He, Lauterio, Andrea, Bongini, Marco, Cucchetti, Alessandro

“… Outcomes of liver transplantation for hepatocellular carcinoma (HCC) are determined by cancer-related and non-related events. Treatments for hepatitis C virus …”
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Assessment of liver function in patients with hepatocellular carcinoma: a new evidence-based approach-the ALBI grade von Johnson, Philip J, Berhane, Sarah, Kagebayashi, Chiaki, Satomura, Shinji, Teng, Mabel, Reeves, Helen L, O'Beirne, James, Fox, Richard, Skowronska, Anna, Palmer, Daniel, Yeo, Winnie, Mo, Frankie, Lai, Paul, Iñarrairaegui, Mercedes, Chan, Stephen L, Sangro, Bruno, Miksad, Rebecca, Tada, Toshifumi, Kumada, Takashi, Toyoda, Hidenori

“… Most patients with hepatocellular carcinoma (HCC) have associated chronic liver disease, the severity of which is currently assessed by the Child-Pugh (C-P) …”
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The Role of Angiogenesis in Hepatocellular Carcinoma von Morse, Michael A, Sun, Weijing, Kim, Richard, He, Aiwu Ruth, Abada, Paolo B, Mynderse, Michelle, Finn, Richard S

“… Hepatocellular carcinoma (HCC) accounts for about 90% of all primary liver cancers and is the second leading cause of cancer-related deaths worldwide. The …”
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A Large‐scale, multicenter serum metabolite biomarker identification study for the early detection of hepatocellular carcinoma von Luo, Ping, Yin, Peiyuan, Hua, Rui, Tan, Yexiong, Li, Zaifang, Qiu, Gaokun, Yin, Zhenyu, Xie, Xingwang, Wang, Xiaomei, Chen, Wenbin, Zhou, Lina, Wang, Xiaolin, Li, Yanli, Chen, Hongsong, Gao, Ling, Lu, Xin, Wu, Tangchun, Wang, Hongyang, Niu, Junqi, Xu, Guowang

“… Hepatocellular carcinoma (HCC) is the third most lethal cancer worldwide. The lack of effective biomarkers for the early detection of HCC results in …”
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Evaluating the Impact of Liver Vasculature Model Complexity for Estimating Dose to Circulating Blood During Radiation Therapy von Xing, Shu, Correa-Alfonso, Camilo M, Shin, Jungwook, Pursley, Jennifer, Depauw, Nicolas, Domal, Sean, Withrow, Julia, Bolch, Wesley, Grassberger, Clemens, Paganetti, Harald

“… To assess the impact of liver model complexity on the estimated radiation dose to circulating blood during radiation therapy. Six patients with hepatocellular …”
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Circulating tumour DNA methylation markers for diagnosis and prognosis of hepatocellular carcinoma von Xu, Rui-hua, Wei, Wei, Krawczyk, Michal, Wang, Wenqiu, Luo, Huiyan, Flagg, Ken, Yi, Shaohua, Shi, William, Quan, Qingli, Li, Kang, Zheng, Lianghong, Zhang, Heng, Caughey, Bennett A., Zhao, Qi, Hou, Jiayi, Zhang, Runze, Xu, Yanxin, Cai, Huimin, Li, Gen, Hou, Rui, Zhong, Zheng, Lin, Danni, Fu, Xin, Zhu, Jie, Duan, Yaou, Yu, Meixing, Ying, Binwu, Zhang, Wengeng, Wang, Juan, Zhang, Edward, Zhang, Charlotte, Li, Oulan, Guo, Rongping, Carter, Hannah, Zhu, Jian-kang, Hao, Xiaoke, Zhang, Kang

“… An effective blood-based method for the diagnosis and prognosis of hepatocellular carcinoma (HCC) has not yet been developed. Circulating tumour DNA (ctDNA) …”
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Glypican‐3: A promising biomarker for hepatocellular carcinoma diagnosis and treatment von Zhou, Fubo, Shang, Wenting, Yu, Xiaoling, Tian, Jie

“… Liver cancer is the second leading cause of cancer‐related deaths, and hepatocellular carcinoma (HCC) is the most common type. Therefore, molecular targets are …”
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Preoperative gadoxetic acid–enhanced MRI for predicting microvascular invasion in patients with single hepatocellular carcinoma von Lee, Sunyoung, Kim, Seong Hyun, Lee, Ji Eun, Sinn, Dong Hyun, Park, Cheol Keun

“… [Display omitted] •MR imaging features were independent predictors for microvascular invasion of HCC.•MR imaging findings can be used as a biomarker for …”
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Randomized Trial of Hepatic Artery Embolization for Hepatocellular Carcinoma Using Doxorubicin-Eluting Microspheres Compared With Embolization With Microspheres Alone von Brown, Karen T, Do, Richard K, Gonen, Mithat, Covey, Anne M, Getrajdman, George I, Sofocleous, Constantinos T, Jarnagin, William R, D'Angelica, Michael I, Allen, Peter J, Erinjeri, Joseph P, Brody, Lynn A, O'Neill, Gerald P, Johnson, Kristian N, Garcia, Alessandra R, Beattie, Christopher, Zhao, Binsheng, Solomon, Stephen B, Schwartz, Lawrence H, DeMatteo, Ronald, Abou-Alfa, Ghassan K

“… Transarterial chemoembolization is accepted therapy for hepatocellular carcinoma (HCC). No randomized trial has demonstrated superiority of chemoembolization …”
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Phase II trial evaluating the clinical and biologic effects of bevacizumab in unresectable hepatocellular carcinoma von Siegel, Abby B, Cohen, Emil I, Ocean, Allyson, Lehrer, Deborah, Goldenberg, Alec, Knox, Jennifer J, Chen, Helen, Clark-Garvey, Sean, Weinberg, Alan, Mandeli, John, Christos, Paul, Mazumdar, Madhu, Popa, Elizabeta, Brown, Jr, Robert S, Rafii, Shahin, Schwartz, Jonathan D

“… To determine the clinical and biologic effects of bevacizumab, an anti-vascular endothelial growth factor (VEGF) monoclonal antibody, in unresectable …”
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GALAD Score for Hepatocellular Carcinoma Detection in Comparison with Liver Ultrasound and Proposal of GALADUS Score von Yang, Ju Dong, Addissie, Benyam D, Mara, Kristin C, Harmsen, William S, Dai, Jianliang, Zhang, Ning, Wongjarupong, Nicha, Ali, Hawa M, Ali, Hamdi A, Hassan, Fatima A, Lavu, Sravanthi, Cvinar, Jessica L, Giama, Nasra H, Moser, Catherine D, Miyabe, Katsuyuki, Allotey, Loretta K, Algeciras-Schimnich, Alicia, Theobald, J Paul, Ward, Melissa M, Nguyen, Mindie H, Befeler, Alex S, Reddy, K Rajender, Schwartz, Myron, Harnois, Denise M, Yamada, Hiroyuki, Srivastava, Sudhir, Rinaudo, Jo Ann, Gores, Gregory J, Feng, Ziding, Marrero, Jorge A, Roberts, Lewis R

“… The GALAD score is a serum biomarker-based model that predicts the probability of having hepatocellular carcinoma (HCC) in patients with chronic liver disease …”
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Prognostic factors and predictors of sorafenib benefit in patients with hepatocellular carcinoma: Analysis of two phase III studies von Bruix, Jordi, Cheng, Ann-Lii, Meinhardt, Gerold, Nakajima, Keiko, De Sanctis, Yoriko, Llovet, Josep

“… [Display omitted] •Prognostic and predictive factors for survival in patients with HCC were identified.•Vascular invasion, high alpha-fetoprotein, and high …”
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aMAP risk score predicts hepatocellular carcinoma development in patients with chronic hepatitis von Fan, Rong, Papatheodoridis, George, Sun, Jian, Innes, Hamish, Toyoda, Hidenori, Xie, Qing, Mo, Shuyuan, Sypsa, Vana, Guha, Indra Neil, Kumada, Takashi, Niu, Junqi, Dalekos, George, Yasuda, Satoshi, Barnes, Eleanor, Lian, Jianqi, Suri, Vithika, Idilman, Ramazan, Barclay, Stephen T., Dou, Xiaoguang, Berg, Thomas, Hayes, Peter C., Flaherty, John F., Zhou, Yuanping, Zhang, Zhengang, Buti, Maria, Hutchinson, Sharon J., Guo, Yabing, Calleja, Jose Luis, Lin, Lanjia, Zhao, Longfeng, Chen, Yongpeng, Janssen, Harry L.A., Zhu, Chaonan, Shi, Lei, Tang, Xiaoping, Gaggar, Anuj, Wei, Lai, Jia, Jidong, Irving, William L., Johnson, Philip J., Lampertico, Pietro, Hou, Jinlin

“… Hepatocellular carcinoma (HCC) is the leading cause of death in patients with chronic hepatitis. In this international collaboration, we sought to develop a …”
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Combined Effect of PNPLA3, TM6SF2, and HSD17B13 Variants on Risk of Cirrhosis and Hepatocellular Carcinoma in the General Population von Gellert‐Kristensen, Helene, Richardson, Tom G., Davey Smith, George, Nordestgaard, Børge G., Tybjærg‐Hansen, Anne, Stender, Stefan

“… Background and Aims We hypothesized that a genetic risk score (GRS) for fatty liver disease influences the risk of cirrhosis and hepatocellular carcinoma …”
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Circulating tumor-derived DNA is shorter than somatic DNA in plasma von Mouliere, Florent, Rosenfeld, Nitzan

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Delivery of nitric oxide with a nanocarrier promotes tumour vessel normalization and potentiates anti-cancer therapies von Sung, Yun-Chieh, Jin, Pei-Ru, Chu, Li-An, Hsu, Fu-Fei, Wang, Mei-Ren, Chang, Chih-Chun, Chiou, Show-Jen, Qiu, Jiantai Timothy, Gao, Dong-Yu, Lin, Chu-Chi, Chen, Yu-Sing, Hsu, Yi-Chiung, Wang, Jane, Wang, Fu-Nien, Yu, Pei-Lun, Chiang, Ann-Shyn, Wu, Anthony Yan-Tang, Ko, John Jun-Sheng, Lai, Charles Pin-Kuang, Lu, Tsai-Te, Chen, Yunching

“… Abnormal tumour vasculature has a significant impact on tumour progression and response to therapy. Nitric oxide (NO) regulates angiogenesis and maintains …”
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