Search Results - "CALCIUM"

Ca2+ channel subtypes and pharmacology in the kidney by Hayashi, Koichi, Wakino, Shu, Sugano, Naoki, Ozawa, Yuri, Homma, Koichiro, Saruta, Takao

“…A large body of evidence has accrued indicating that voltage-gated Ca(2+) channel subtypes, including L-, T-, N-, and P/Q-type, are present within renal…”
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Opposite Roles in Short-Term Plasticity for N-Type and P/Q-Type Voltage-Dependent Calcium Channels in GABAergic Neuronal Connections in the Rat Cerebral Cortex by Yamamoto, Kiyofumi, Kobayashi, Masayuki

“…Neurotransmitter release is triggered by Ca influx through voltage-dependent Ca channels (VDCCs). Distinct expression patterns of VDCC subtypes localized on…”
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Calcium Homeostasis, Transporters, and Blockers in Health and Diseases of the Cardiovascular System by Bkaily, Ghassan, Jacques, Danielle

“…Calcium is a highly positively charged ionic species. It regulates all cell types’ functions and is an important second messenger that controls and triggers…”
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Fabrication of chondroitin sulfate calcium complex and its chondrocyte proliferation in vitro by Shen, Qingshan, Zhang, Chunhui, Mo, Haizhen, Zhang, Hongru, Qin, Xiaojie, Li, Juan, Zhang, Zhiqiang, Richel, Aurore

“…[Display omitted] •Chondroitin sulfate calcium complex (CSCa) was fabricated by cation exchange method.•Characterization of CSCa was analyzed by EDS, AFM,…”
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Glucose-mediated inhibition of calcium-activated potassium channels limits α-cell calcium influx and glucagon secretion by Dickerson, Matthew T, Dadi, Prasanna K, Altman, Molly K, Verlage, Kenneth R, Thorson, Ariel S, Jordan, Kelli L, Vierra, Nicholas C, Amarnath, Gautami, Jacobson, David A

“…Pancreatic α-cells exhibit oscillations in cytosolic Ca (Ca ), which control pulsatile glucagon (GCG) secretion. However, the mechanisms that modulate α-cell…”
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Improved calcium sensor GCaMP-X overcomes the calcium channel perturbations induced by the calmodulin in GCaMP by Yang, Yaxiong, Liu, Nan, He, Yuanyuan, Liu, Yuxia, Ge, Lin, Zou, Linzhi, Song, Sen, Xiong, Wei, Liu, Xiaodong

“…GCaMP, one popular type of genetically-encoded Ca 2+ indicator, has been associated with various side-effects. Here we unveil the intrinsic problem prevailing…”
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Discovery of nitrate–CPK–NLP signalling in central nutrient–growth networks by Liu, Kun-hsiang, Niu, Yajie, Konishi, Mineko, Wu, Yue, Du, Hao, Sun Chung, Hoo, Li, Lei, Boudsocq, Marie, McCormack, Matthew, Maekawa, Shugo, Ishida, Tetsuya, Zhang, Chao, Shokat, Kevan, Yanagisawa, Shuichi, Sheen, Jen

“…Nutrient signalling integrates and coordinates gene expression, metabolism and growth. However, its primary molecular mechanisms remain incompletely understood…”
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Molecular nature and physiological role of the mitochondrial calcium uniporter channel by Alevriadou, B Rita, Patel, Akshar, Noble, Megan, Ghosh, Sagnika, Gohil, Vishal M, Stathopulos, Peter B, Madesh, Muniswamy

“…Calcium (Ca ) signaling is critical for cell function and cell survival. Mitochondria play a major role in regulating the intracellular Ca concentration ([Ca ]…”
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The Physiology, Pathology, and Pharmacology of Voltage-Gated Calcium Channels and Their Future Therapeutic Potential by Zamponi, Gerald W, Striessnig, Joerg, Koschak, Alexandra, Dolphin, Annette C

“…Voltage-gated calcium channels are required for many key functions in the body. In this review, the different subtypes of voltage-gated calcium channels are…”
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The calcium transporter ANNEXIN1 mediates cold‐induced calcium signaling and freezing tolerance in plants by Liu, Qiangbo, Ding, Yanglin, Shi, Yiting, Ma, Liang, Wang, Yi, Song, Chunpeng, Wilkins, Katie A, Davies, Julia M, Knight, Heather, Knight, Marc R, Gong, Zhizhong, Guo, Yan, Yang, Shuhua

“…The transient elevation of cytosolic free calcium concentration ([Ca 2+ ] cyt ) induced by cold stress is a well‐established phenomenon; however, the…”
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Calcium at the Center of Cell Signaling: Interplay between Endoplasmic Reticulum, Mitochondria, and Lysosomes by Raffaello, Anna, Mammucari, Cristina, Gherardi, Gaia, Rizzuto, Rosario

“…In recent years, rapid discoveries have been made relating to Ca2+ handling at specific organelles that have important implications for whole-cell Ca2+…”
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Mitochondrial calcium exchange in physiology and disease by Garbincius, Joanne F, Elrod, John W

“…The uptake of calcium into and extrusion of calcium from the mitochondrial matrix is a fundamental biological process that has critical effects on cellular…”
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Neuronal calcium signaling: function and dysfunction by Brini, Marisa, Calì, Tito, Ottolini, Denis, Carafoli, Ernesto

“…Calcium (Ca²⁺) is an universal second messenger that regulates the most important activities of all eukaryotic cells. It is of critical importance to neurons…”
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P-type calcium ATPases play important roles in biotic and abiotic stress signaling by Chandan, Kumari, Gupta, Meenakshi, Ahmad, Altaf, Sarwat, Maryam

“…Main conclusion Knowledge of Ca 2+ -ATPases is imperative for improving crop quality/ food security, highly threatened due to global warming. Ca 2+ -ATPases…”
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Genetic variants of calcium and vitamin D metabolism in kidney stone disease by Howles, Sarah A., Wiberg, Akira, Goldsworthy, Michelle, Bayliss, Asha L., Gluck, Anna K., Ng, Michael, Grout, Emily, Tanikawa, Chizu, Kamatani, Yoichiro, Terao, Chikashi, Takahashi, Atsushi, Kubo, Michiaki, Matsuda, Koichi, Thakker, Rajesh V., Turney, Benjamin W., Furniss, Dominic

“…Kidney stone disease (nephrolithiasis) is a major clinical and economic health burden with a heritability of ~45–60%. We present genome-wide association…”
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The structure of the MICU1‐MICU2 complex unveils the regulation of the mitochondrial calcium uniporter by Wu, Wenping, Shen, Qingya, Zhang, Ruiling, Qiu, Zhiyu, Wang, Youjun, Zheng, Jimin, Jia, Zongchao

“…The MICU1‐MICU2 heterodimer regulates the mitochondrial calcium uniporter (MCU) and mitochondrial calcium uptake. Herein, we present two crystal structures of…”
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Adrenergic Regulation of Calcium Channels in the Heart by Papa, Arianne, Kushner, Jared, Marx, Steven O

“…Each heartbeat is initiated by the action potential, an electrical signal that depolarizes the plasma membrane and activates a cycle of calcium influx via…”
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Why Calcium? How Calcium Became the Best Communicator by Carafoli, Ernesto, Krebs, Joachim

“…Calcium carries messages to virtually all important functions of cells. Although it was already active in unicellular organisms, its role became universally…”
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Morphological profile determines the frequency of spontaneous calcium events in astrocytic processes by Wu, Yu‐Wei, Gordleeva, Susan, Tang, Xiaofang, Shih, Pei‐Yu, Dembitskaya, Yulia, Semyanov, Alexey

“…Astrocytes express a complex repertoire of intracellular Ca2+ transients (events) that represent a major form of signaling within individual cells and in…”
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Evidence supporting the MICU1 occlusion mechanism and against the potentiation model in the mitochondrial calcium uniporter complex by Tsai, Chen-Wei, Liu, Tsung-Yun, Chao, Fan-Yi, Tu, Yung-Chi, Rodriguez, Madison X, Van Keuren, Anna M, Ma, Zhiwei, Bankston, John, Tsai, Ming-Feng

“…The mitochondrial calcium uniporter is a Ca channel that imports cytoplasmic Ca into the mitochondrial matrix to regulate cell bioenergetics, intracellular Ca…”
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