Výsledky vyhľadávania - "Buchmeier, Michael J."

Severe Acute Respiratory Syndrome Coronavirus Nonstructural Proteins 3, 4, and 6 Induce Double-Membrane Vesicles Autor Angelini, Megan M., Akhlaghpour, Marzieh, Neuman, Benjamin W., Buchmeier, Michael J.

“…Coronaviruses (CoV), like other positive-stranded RNA viruses, redirect and rearrange host cell membranes for use as part of the viral genome replication and…”
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A structural analysis of M protein in coronavirus assembly and morphology Autor Neuman, Benjamin W., Kiss, Gabriella, Kunding, Andreas H., Bhella, David, Baksh, M. Fazil, Connelly, Stephen, Droese, Ben, Klaus, Joseph P., Makino, Shinji, Sawicki, Stanley G., Siddell, Stuart G., Stamou, Dimitrios G., Wilson, Ian A., Kuhn, Peter, Buchmeier, Michael J.

“…The M protein of coronavirus plays a central role in virus assembly, turning cellular membranes into workshops where virus and host factors come together to…”
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ICTV Virus Taxonomy Profile: Arenaviridae 2023 Autor Radoshitzky, Sheli R, Buchmeier, Michael J, Charrel, Rémi N, Gonzalez, Jean-Paul J, Günther, Stephan, Hepojoki, Jussi, Kuhn, Jens H, Lukashevich, Igor S, Romanowski, Víctor, Salvato, Maria S, Sironi, Manuela, Stenglein, Mark D, Torre, Juan Carlos de la

“…is a family for ambisense RNA viruses with genomes of about 10.5 kb that infect mammals, snakes, and fish. The arenavirid genome consists of two or three…”
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Severe acute respiratory syndrome coronavirus nonstructural protein 2 interacts with a host protein complex involved in mitochondrial biogenesis and intracellular signaling Autor Cornillez-Ty, Cromwell T, Liao, Lujian, Yates, 3rd, John R, Kuhn, Peter, Buchmeier, Michael J

“…The severe acute respiratory syndrome coronavirus (SARS-CoV) generates 16 nonstructural proteins (nsp's) through proteolytic cleavage of a large precursor…”
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Does form meet function in the coronavirus replicative organelle? Autor Neuman, Benjamin W., Angelini, Megan M., Buchmeier, Michael J.

“…•Most, but not all, +RNA viruses form intracellular replicative organelles.•The hallmark of nidovirus replicative organelles is membrane pairing, not…”
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Supramolecular architecture of severe acute respiratory syndrome coronavirus revealed by electron cryomicroscopy Autor Neuman, Benjamin W, Adair, Brian D, Yoshioka, Craig, Quispe, Joel D, Orca, Gretchen, Kuhn, Peter, Milligan, Ronald A, Yeager, Mark, Buchmeier, Michael J

“…Coronavirus particles are enveloped and pleomorphic and are thus refractory to crystallization and symmetry-assisted reconstruction. A novel methodology of…”
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Arenavirus Stable Signal Peptide Is the Keystone Subunit for Glycoprotein Complex Organization Autor Bederka, Lydia H., Bonhomme, Cyrille J., Ling, Emily L., Buchmeier, Michael J.

“…The rodent arenavirus glycoprotein complex encodes a stable signal peptide (SSP) that is an essential structural component of mature virions. The SSP, GP1, and…”
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Proteomics analysis unravels the functional repertoire of coronavirus nonstructural protein 3 Autor Neuman, Benjamin W, Joseph, Jeremiah S, Saikatendu, Kumar S, Serrano, Pedro, Chatterjee, Amarnath, Johnson, Margaret A, Liao, Lujian, Klaus, Joseph P, Yates, 3rd, John R, Wüthrich, Kurt, Stevens, Raymond C, Buchmeier, Michael J, Kuhn, Peter

“…Severe acute respiratory syndrome (SARS) coronavirus infection and growth are dependent on initiating signaling and enzyme actions upon viral entry into the…”
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Conserved residues in Lassa fever virus Z protein modulate viral infectivity at the level of the ribonucleoprotein Autor Capul, Althea A, de la Torre, Juan Carlos, Buchmeier, Michael J

“…Arenaviruses are negative-strand RNA viruses that cause human diseases such as lymphocytic choriomeningitis, Bolivian hemorrhagic fever, and Lassa hemorrhagic…”
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Nuclear magnetic resonance structure of the nucleic acid-binding domain of severe acute respiratory syndrome coronavirus nonstructural protein 3 Autor Serrano, Pedro, Johnson, Margaret A, Chatterjee, Amarnath, Neuman, Benjamin W, Joseph, Jeremiah S, Buchmeier, Michael J, Kuhn, Peter, Wüthrich, Kurt

“…The nuclear magnetic resonance (NMR) structure of a globular domain of residues 1071 to 1178 within the previously annotated nucleic acid-binding region (NAB)…”
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Ribonucleocapsid formation of severe acute respiratory syndrome coronavirus through molecular action of the N-terminal domain of N protein Autor Saikatendu, Kumar Singh, Joseph, Jeremiah S, Subramanian, Vanitha, Neuman, Benjamin W, Buchmeier, Michael J, Stevens, Raymond C, Kuhn, Peter

“…Conserved among all coronaviruses are four structural proteins: the matrix (M), small envelope (E), and spike (S) proteins that are embedded in the viral…”
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The CD8+ T-cell response to lymphocytic choriomeningitis virus involves the L antigen: uncovering new tricks for an old virus Autor Kotturi, Maya F, Peters, Bjoern, Buendia-Laysa, Jr, Fernando, Sidney, John, Oseroff, Carla, Botten, Jason, Grey, Howard, Buchmeier, Michael J, Sette, Alessandro

“…CD8(+) T-cell responses control lymphocytic choriomeningitis virus (LCMV) infection in H-2(b) mice. Although antigen-specific responses against LCMV infection…”
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Arenavirus Z-glycoprotein association requires Z myristoylation but not functional RING or late domains Autor Capul, Althea A, Perez, Mar, Burke, Emily, Kunz, Stefan, Buchmeier, Michael J, de la Torre, Juan C

“…Generation of infectious arenavirus-like particles requires the virus RING finger Z protein and surface glycoprotein precursor (GPC) and the correct processing…”
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DC-SIGN and DC-SIGNR Bind Ebola Glycoproteins and Enhance Infection of Macrophages and Endothelial Cells Autor Simmons, Graham, Reeves, Jacqueline D., Grogan, Case C., Vandenberghe, Luk H., Baribaud, Frédéric, Whitbeck, J.Charles, Burke, Emily, Buchmeier, Michael J., Soilleux, Elizabeth J., Riley, James L., Doms, Robert W., Bates, Paul, Pöhlmann, Stefan

“…Ebola virus exhibits a broad cellular tropism in vitro. In humans and animal models, virus is found in most tissues and organs during the latter stages of…”
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LCMV Glycosylation Modulates Viral Fitness and Cell Tropism Autor Bonhomme, Cyrille J., Knopp, Kristeene A., Bederka, Lydia H., Angelini, Megan M., Buchmeier, Michael J.

“…The glycoprotein (GP) of arenaviruses is glycosylated at 11 conserved N-glycosylation sites. We constructed recombinant lymphocytic choriomeningitis virus…”
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Distinct neural stem cell tropism, early immune activation, and choroid plexus pathology following coxsackievirus infection in the neonatal central nervous system Autor Puccini, Jenna M, Ruller, Chelsea M, Robinson, Scott M, Knopp, Kristeene A, Buchmeier, Michael J, Doran, Kelly S, Feuer, Ralph

“…Coxsackievirus B3 (CVB3) and lymphocytic choriomeningitis virus (LCMV) are both neurotropic RNA viruses, which can establish a persistent infection and cause…”
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Crystal structure of a monomeric form of severe acute respiratory syndrome coronavirus endonuclease nsp15 suggests a role for hexamerization as an allosteric switch Autor Joseph, Jeremiah S, Saikatendu, Kumar Singh, Subramanian, Vanitha, Neuman, Benjamin W, Buchmeier, Michael J, Stevens, Raymond C, Kuhn, Peter

“…Mature nonstructural protein-15 (nsp15) from the severe acute respiratory syndrome coronavirus (SARS-CoV) contains a novel uridylate-specific Mn2+-dependent…”
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Single Nucleoprotein Residue Modulates Arenavirus Replication Complex Formation Autor Knopp, Kristeene A., Ngo, Tuan, Gershon, Paul D., Buchmeier, Michael J.

“…The Arenaviridae are enveloped, negative-sense RNA viruses with several family members that cause hemorrhagic fevers. This work provides immunofluorescence…”
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Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models Autor Burrer, Renaud, Neuman, Benjamin W, Ting, Joey P C, Stein, David A, Moulton, Hong M, Iversen, Patrick L, Kuhn, Peter, Buchmeier, Michael J

“…The recent emergence of novel pathogenic human and animal coronaviruses has highlighted the need for antiviral therapies that are effective against a spectrum…”
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Crystal structure of nonstructural protein 10 from the severe acute respiratory syndrome coronavirus reveals a novel fold with two zinc-binding motifs Autor Joseph, Jeremiah S, Saikatendu, Kumar Singh, Subramanian, Vanitha, Neuman, Benjamin W, Brooun, Alexei, Griffith, Mark, Moy, Kin, Yadav, Maneesh K, Velasquez, Jeffrey, Buchmeier, Michael J, Stevens, Raymond C, Kuhn, Peter

“…The severe acute respiratory syndrome coronavirus (SARS-CoV) possesses a large 29.7-kb positive-stranded RNA genome. The first open reading frame encodes…”
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