Suchergebnisse - "Brownlee, Wallace J"

Diagnosis of multiple sclerosis: progress and challenges von Brownlee, Wallace J, Hardy, Todd A, Fazekas, Franz, Miller, David H

“… The diagnosis of multiple sclerosis is based on neurological symptoms and signs, alongside evidence of dissemination of CNS lesions in space and time. MRI is …”
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Early imaging predictors of long-term outcomes in relapse-onset multiple sclerosis von Brownlee, Wallace J, Altmann, Dan R, Prados, Ferran, Miszkiel, Katherine A, Eshaghi, Arman, Gandini Wheeler-Kingshott, Claudia A M, Barkhof, Frederik, Ciccarelli, Olga

“… The clinical course of relapse-onset multiple sclerosis is highly variable. Demographic factors, clinical features and global brain T2 lesion load have limited …”
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Longitudinal spinal cord atrophy in multiple sclerosis using the generalized boundary shift integral von Moccia, Marcello, Prados, Ferran, Filippi, Massimo, Rocca, Maria A., Valsasina, Paola, Brownlee, Wallace J., Zecca, Chiara, Gallo, Antonio, Rovira, Alex, Gass, Achim, Palace, Jacqueline, Lukas, Carsten, Vrenken, Hugo, Ourselin, Sebastien, Gandini Wheeler‐Kingshott, Claudia A. M., Ciccarelli, Olga, Barkhof, Frederik

“… Objective Spinal cord atrophy is a clinically relevant feature of multiple sclerosis (MS), but longitudinal assessments on magnetic resonance imaging using …”
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Twenty years of natalizumab in multiple sclerosis: lessons learned and future outlook von Klotz, Luisa, Berger, Thomas, Brownlee, Wallace J., Chan, Andrew, Lycke, Jan, Oreja-Guevara, Celia, Palavra, Filipe, Sacca, Francesco, Sejbaek, Tobias, Weber, Martin S., Giovannoni, Gavin

“… Twenty years on from its initial approval as the first monoclonal antibody for the treatment of multiple sclerosis (MS), natalizumab remains a valuable …”
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Longitudinal Assessment of Multiple Sclerosis with the Brain‐Age Paradigm von Cole PhD, James H., Raffel MD, Joel, Friede PhD, Tim, Eshaghi MD, PhD, Arman, Brownlee PhD, FRACP, Wallace J., Chard MD, PhD, Declan, De Stefano MD, PhD, Nicola, Enzinger MD, Christian, Pirpamer MSc, Lukas, Filippi MD, FEAN, Massimo, Gasperini MD, Claudio, Rocca MD, Maria Assunta, Rovira MD, Alex, Ruggieri MD, Serena, Sastre‐Garriga MD, PhD, Jaume, Stromillo MD, PhD, Maria Laura, Uitdehaag MD, PhD, Bernard M. J., Vrenken PhD, Hugo, Barkhof MD PhD, Frederik, Nicholas MD, PhD, Richard, Ciccarelli PhD, FRCP, Olga

“… Objective During the natural course of multiple sclerosis (MS), the brain is exposed to aging as well as disease effects. Brain aging can be modeled …”
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Diagnostic and treatment challenges in patients at the borderlands of the idiopathic inflammatory demyelinating disorders von Brownlee, Wallace J

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The prognostic significance of early blood neurofilament light chain concentration and magnetic resonance imaging variables in relapse‐onset multiple sclerosis von Williams, Thomas, Heslegrave, Amanda, Zetterberg, Henrik, Miszkiel, Katherine A, Barkhof, Frederik, Ciccarelli, Olga, Brownlee, Wallace J, Chataway, Jeremy

“… Background Improved prognostication remains vital in multiple sclerosis to inform personalized treatment approaches. Blood neurofilament light (bNfL) is a …”
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Cladribine-induced liver injury: Implications for practice von Brownlee, Wallace J

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Disease-modifying therapies for multiple sclerosis von De Angelis, Floriana, John, Nevin A, Brownlee, Wallace J

“… What you need to know: Disease-modifying therapies (DMTs) early in the course of active relapsing multiple sclerosis can prevent relapses, new brain and spinal …”
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Navigating pregnancy in women with NMOSD in the monoclonal antibody era von Brownlee, Wallace J, Dobson, Ruth

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COVID-19 and high-efficacy multiple sclerosis therapies: Time for business as usual? von Brownlee, Wallace J

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Neurology in the time of COVID-19 von Manji, Hadi, Carr, Aisling S, Brownlee, Wallace J, Lunn, Michael P

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Differential diagnosis of multiple sclerosis: The better explanations in clinical practice von Brownlee, Wallace J

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Optic Nerve in Multiple Sclerosis Diagnostic Criteria: An Aye to the Eyes? von Brownlee, Wallace J, Galetta, Steven

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Misdiagnosis of multiple sclerosis: If you have a hammer, everything looks like a nail? von Brownlee, Wallace J

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Instead of tweaking the diagnostic criteria for MS in those with CIS, we should develop diagnostic criteria that distinguish MS from other conditions - No von Brownlee, Wallace J

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Inclusion of optic nerve involvement in dissemination in space criteria for multiple sclerosis von Brownlee, Wallace J, Miszkiel, Katherine A, Tur, Carmen, Barkhof, Frederik, Miller, David H, Ciccarelli, Olga

“… To investigate the effect of including optic nerve involvement in dissemination in space (DIS) criteria for diagnosis of multiple sclerosis (MS) in patients …”
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Differential diagnosis of suspected multiple sclerosis: an updated consensus approach von Solomon, Andrew J, Arrambide, Georgina, Brownlee, Wallace J, Flanagan, Eoin P, Amato, Maria Pia, Amezcua, Lilyana, Banwell, Brenda L, Barkhof, Frederik, Corboy, John R, Correale, Jorge, Fujihara, Kazuo, Graves, Jennifer, Harnegie, Mary Pat, Hemmer, Bernhard, Lechner-Scott, Jeannette, Marrie, Ruth Ann, Newsome, Scott D, Rocca, Maria A, Royal, Walter, Waubant, Emmanuelle L, Yamout, Bassem, Cohen, Jeffrey A

“… Accurate diagnosis of multiple sclerosis requires careful attention to its differential diagnosis—many disorders can mimic the clinical manifestations and …”
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Deep gray matter volume loss drives disability worsening in multiple sclerosis von Eshaghi, Arman, Prados, Ferran, Brownlee, Wallace J., Altmann, Daniel R., Tur, Carmen, Cardoso, M. Jorge, De Angelis, Floriana, van de Pavert, Steven H., Cawley, Niamh, De Stefano, Nicola, Stromillo, M. Laura, Battaglini, Marco, Ruggieri, Serena, Gasperini, Claudio, Filippi, Massimo, Rocca, Maria A., Rovira, Alex, Sastre‐Garriga, Jaume, Vrenken, Hugo, Leurs, Cyra E., Killestein, Joep, Pirpamer, Lukas, Enzinger, Christian, Ourselin, Sebastien, Wheeler‐Kingshott, Claudia A.M. Gandini, Chard, Declan, Thompson, Alan J., Alexander, Daniel C., Barkhof, Frederik, Ciccarelli, Olga

“… Objective Gray matter (GM) atrophy occurs in all multiple sclerosis (MS) phenotypes. We investigated whether there is a spatiotemporal pattern of GM atrophy …”
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Progression of regional grey matter atrophy in multiple sclerosis von Eshaghi, Arman, Marinescu, Razvan V, Young, Alexandra L, Firth, Nicholas C, Prados, Ferran, Jorge Cardoso, M, Tur, Carmen, De Angelis, Floriana, Cawley, Niamh, Brownlee, Wallace J, De Stefano, Nicola, Laura Stromillo, M, Battaglini, Marco, Ruggieri, Serena, Gasperini, Claudio, Filippi, Massimo, Rocca, Maria A, Rovira, Alex, Sastre-Garriga, Jaume, Geurts, Jeroen J G, Vrenken, Hugo, Wottschel, Viktor, Leurs, Cyra E, Uitdehaag, Bernard, Pirpamer, Lukas, Enzinger, Christian, Ourselin, Sebastien, Gandini Wheeler-Kingshott, Claudia A, Chard, Declan, Thompson, Alan J, Barkhof, Frederik, Alexander, Daniel C, Ciccarelli, Olga

“… See Stankoff and Louapre (doi:10.1093/brain/awy114) for a scientific commentary on this article. Grey matter atrophy in multiple sclerosis affects certain …”
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