Suchergebnisse - "Braet, Filip"

Three-dimensional ultrastructure of giant mitochondria in human non-alcoholic fatty liver disease von Shami, Gerald J., Cheng, Delfine, Verhaegh, Pauline, Koek, Ger, Wisse, Eddie, Braet, Filip

“… Giant mitochondria are peculiarly shaped, extremely large mitochondria in hepatic parenchymal cells, the internal structure of which is characterised by …”
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‘Muscle superman’ Cristobal Guillermo dos Remedios: five decades of endless energy von Braet, Filip

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Glomerular endothelial cell fenestrations: an integral component of the glomerular filtration barrier von Satchell, Simon C, Braet, Filip

“… Glomerular endothelial cell (GEnC) fenestrations are analogous to podocyte filtration slits, but their important contribution to the glomerular filtration …”
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Tracking Fenestrae Dynamics in Live Murine Liver Sinusoidal Endothelial Cells von Zapotoczny, Bartlomiej, Szafranska, Karolina, Kus, Edyta, Braet, Filip, Wisse, Eddie, Chlopicki, Stefan, Szymonski, Marek

“… The fenestrae of liver sinusoidal endothelial cells (LSECs) allow passive transport of solutes, macromolecules, and particulate material between the sinusoidal …”
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Carbon Nanomaterials in Biosensors: Should You Use Nanotubes or Graphene von Yang, Wenrong, Ratinac, Kyle R, Ringer, Simon P, Thordarson, Pall, Gooding, J. Justin, Braet, Filip

“… From diagnosis of life-threatening diseases to detection of biological agents in warfare or terrorist attacks, biosensors are becoming a critical part of …”
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Giant mitochondria in cardiomyocytes: cellular architecture in health and disease von Li, Amy, Shami, Gerald J., Griffiths, Lisa, Lal, Sean, Irving, Helen, Braet, Filip

“… Giant mitochondria are frequently observed in different disease models within the brain, kidney, and liver. In cardiac muscle, these enlarged organelles are …”
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Graphene and Related Materials in Electrochemical Sensing von Ratinac, Kyle R., Yang, Wenrong, Gooding, J. Justin, Thordarson, Pall, Braet, Filip

“… Graphene and related materials, such as graphene oxide and reduced graphene oxide, have come to the forefront of research in electrochemical sensors during …”
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Disruption of Plasmodium falciparum kinetochore proteins destabilises the nexus between the centrosome equivalent and the mitotic apparatus von Li, Jiahong, Shami, Gerald J., Liffner, Benjamin, Cho, Ellie, Braet, Filip, Duraisingh, Manoj T., Absalon, Sabrina, Dixon, Matthew W. A., Tilley, Leann

“… Plasmodium falciparum is the causative agent of malaria and remains a pathogen of global importance. Asexual blood stage replication, via a process called …”
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Synthesis, characterization, and multilayer assembly of pH sensitive graphene-polymer nanocomposites von Liu, Jingquan, Tao, Lei, Yang, Wenrong, Li, Dan, Boyer, Cyrille, Wuhrer, Richard, Braet, Filip, Davis, Thomas P

“… pH sensitive graphene-polymer composites have been prepared by the modification of graphene basal planes with pyrene-terminated poly(2-N,N'-(dimethyl amino …”
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KCa3.1 mediates dysfunction of tubular autophagy in diabetic kidneys via PI3k/Akt/mTOR signaling pathways von Huang, Chunling, Lin, Mike Z., Cheng, Delfine, Braet, Filip, Pollock, Carol A., Chen, Xin-Ming

“… Autophagy is emerging as an important pathway in many diseases including diabetic nephropathy. It is acknowledged that oxidative stress plays a critical role …”
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Fat causes necrosis and inflammation in parenchymal cells in human steatotic liver von Wisse, Eddie, Braet, Filip, Shami, Gerald J., Zapotoczny, Bartlomiej, Vreuls, Celien, Verhaegh, Pauline, Frederik, Peter, Peters, Peters J., Olde Damink, Steven, Koek, Ger

“… Adapted fixation methods for electron microscopy allowed us to study liver cell fine structure in 217 biopsies of intact human livers over the course of …”
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Thioredoxin-interacting protein mediates dysfunction of tubular autophagy in diabetic kidneys through inhibiting autophagic flux von Huang, Chunling, Lin, Mike Z, Cheng, Delfine, Braet, Filip, Pollock, Carol A, Chen, Xin-Ming

“… Thioredoxin-interacting protein (TXNIP) expression is ubiquitous and is induced by a variety of cellular stresses, including high intracellular glucose. TXNIP …”
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Biophysical nanocharacterization of liver sinusoidal endothelial cells through atomic force microscopy von Zapotoczny, Bartlomiej, Braet, Filip, Wisse, Eddie, Lekka, Malgorzata, Szymonski, Marek

“… The structural-functional hallmark of the liver sinusoidal endothelium is the presence of fenestrae grouped in sieve plates. Fenestrae are open membrane bound …”
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Self-Assembled Gels for Biomedical Applications von Truong, Warren Ty, Su, Yingying, Meijer, Joris T., Thordarson, Pall, Braet, Filip

“… Natural and synthetic gel‐like materials have featured heavily in the development of biomaterials for wound healing and other tissue‐engineering purposes. More …”
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Dissolution and degradation of Fmoc-diphenylalanine self-assembled gels results in necrosis at high concentrations in vitro von Truong, Warren Ty, Su, Yingying, Gloria, Danmar, Braet, Filip, Thordarson, Pall

“… Herein we report an approach to assess in vitro cellular responses to the dissolution or degradation products from Fmoc-diphenylalanine (Fmoc-FF) …”
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Structural and functional aspects of liver sinusoidal endothelial cell fenestrae: a review von Braet, Filip, Wisse, Eddie

“… This review provides a detailed overview of the current state of knowledge about the ultrastructure and dynamics of liver sinusoidal endothelial fenestrae …”
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3-D EM exploration of the hepatic microarchitecture – lessons learned from large-volume in situ serial sectioning von Shami, Gerald John, Cheng, Delfine, Huynh, Minh, Vreuls, Celien, Wisse, Eddie, Braet, Filip

“… To-date serial block-face scanning electron microscopy (SBF-SEM) dominates as the premier technique for generating three-dimensional (3-D) data of …”
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Rac1, caveolin-1 and vascular endothelial growth factor -mediated liver sinusoidal endothelial cell angiogenesis von Braet, Filip

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Fixation methods for electron microscopy of human and other liver von Wisse, Eddie, Braet, Filip, Duimel, Hans, Vreuls, Celien, Koek, Ger, Olde Damink, Steven W M, van den Broek, Maartje A J, De Geest, Bart, Dejong, Cees H C, Tateno, Chise, Frederik, Peter

“… For an electron microscopic study of the liver, expertise and complicated, time-consuming processing of hepatic tissues and cells is needed. The interpretation …”
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KCa3.1 Mediates Dysregulation of Mitochondrial Quality Control in Diabetic Kidney Disease von Huang, Chunling, Yi, Hao, Shi, Ying, Cao, Qinghua, Shi, Yin, Cheng, Delfine, Braet, Filip, Chen, Xin-Ming, Pollock, Carol A.

“… Mitochondrial dysfunction is implicated in the pathogenesis of diabetic kidney disease. Mitochondrial quality control is primarily mediated by mitochondrial …”
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