Suchergebnisse - "Bourgey, Mathieu"

Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy von Couturier, Charles P., Ayyadhury, Shamini, Le, Phuong U., Nadaf, Javad, Monlong, Jean, Riva, Gabriele, Allache, Redouane, Baig, Salma, Yan, Xiaohua, Bourgey, Mathieu, Lee, Changseok, Wang, Yu Chang David, Wee Yong, V., Guiot, Marie-Christine, Najafabadi, Hamed, Misic, Bratislav, Antel, Jack, Bourque, Guillaume, Ragoussis, Jiannis, Petrecca, Kevin

“… Cancer stem cells are critical for cancer initiation, development, and treatment resistance. Our understanding of these processes, and how they relate to …”
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A coordinated progression of progenitor cell states initiates urinary tract development von Sanchez-Ferras, Oraly, Pacis, Alain, Sotiropoulou, Maria, Zhang, Yuhong, Wang, Yu Chang, Bourgey, Mathieu, Bourque, Guillaume, Ragoussis, Jiannis, Bouchard, Maxime

“… The kidney and upper urinary tract develop through reciprocal interactions between the ureteric bud and the surrounding mesenchyme. Ureteric bud branching …”
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K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas von Khuong-Quang, Dong-Anh, Buczkowicz, Pawel, Rakopoulos, Patricia, Liu, Xiao-Yang, Fontebasso, Adam M., Bouffet, Eric, Bartels, Ute, Albrecht, Steffen, Schwartzentruber, Jeremy, Letourneau, Louis, Bourgey, Mathieu, Bourque, Guillaume, Montpetit, Alexandre, Bourret, Genevieve, Lepage, Pierre, Fleming, Adam, Lichter, Peter, Kool, Marcel, von Deimling, Andreas, Sturm, Dominik, Korshunov, Andrey, Faury, Damien, Jones, David T., Majewski, Jacek, Pfister, Stefan M., Jabado, Nada, Hawkins, Cynthia

“… Pediatric glioblastomas (GBM) including diffuse intrinsic pontine gliomas (DIPG) are devastating brain tumors with no effective therapy. Here, we investigated …”
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Evolution of chromosome-arm aberrations in breast cancer through genetic network rewiring von Kuzmin, Elena, Baker, Toby M., Lesluyes, Tom, Monlong, Jean, Abe, Kento T., Coelho, Paula P., Schwartz, Michael, Del Corpo, Joseph, Zou, Dongmei, Morin, Genevieve, Pacis, Alain, Yang, Yang, Martinez, Constanza, Barber, Jarrett, Kuasne, Hellen, Li, Rui, Bourgey, Mathieu, Fortier, Anne-Marie, Davison, Peter G., Omeroglu, Atilla, Guiot, Marie-Christine, Morris, Quaid, Kleinman, Claudia L., Huang, Sidong, Gingras, Anne-Claude, Ragoussis, Jiannis, Bourque, Guillaume, Van Loo, Peter, Park, Morag

“… The basal breast cancer subtype is enriched for triple-negative breast cancer (TNBC) and displays consistent large chromosomal deletions. Here, we characterize …”
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Transcriptome atlases of rat brain regions and their adaptation to diabetes resolution following gastrectomy in the Goto-Kakizaki rat von Brial, François, Le Lay, Aurélie, Rouch, Claude, Henrion, Edouard, Bourgey, Mathieu, Bourque, Guillaume, Lathrop, Mark, Magnan, Christophe, Gauguier, Dominique

“… Brain regions drive multiple physiological functions through specific gene expression patterns that adapt to environmental influences, drug treatments and …”
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Author Correction: Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy von Couturier, Charles P., Ayyadhury, Shamini, Le, Phuong U., Nadaf, Javad, Monlong, Jean, Riva, Gabriele, Allache, Redouane, Baig, Salma, Yan, Xiaohua, Bourgey, Mathieu, Lee, Changseok, Wang, Yu Chang David, Yong, V. Wee, Guiot, Marie-Christine, Najafabadi, Hamed, Misic, Bratislav, Antel, Jack, Bourque, Guillaume, Ragoussis, Jiannis, Petrecca, Kevin

“… An amendment to this paper has been published and can be accessed via a link at the top of the paper …”
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A small number of early introductions seeded widespread transmission of SARS-CoV-2 in Québec, Canada von Murall, Carmen Lía, Fournier, Eric, Galvez, Jose Hector, N’Guessan, Arnaud, Reiling, Sarah J., Quirion, Pierre-Olivier, Naderi, Sana, Roy, Anne-Marie, Chen, Shu-Huang, Stretenowich, Paul, Bourgey, Mathieu, Bujold, David, Gregoire, Romain, Lepage, Pierre, St-Cyr, Janick, Willet, Patrick, Dion, Réjean, Charest, Hugues, Lathrop, Mark, Roger, Michel, Bourque, Guillaume, Ragoussis, Jiannis, Shapiro, B. Jesse, Moreira, Sandrine

“… Background Québec was the Canadian province most impacted by COVID-19, with 401,462 cases as of September 24th, 2021, and 11,347 deaths due mostly to a very …”
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Replication analysis confirms the association of ARID5B with childhood B-cell acute lymphoblastic leukemia von Healy, J., Richer, C., Bourgey, M., Kritikou, E. A., Sinnett, D.

“… Although childhood acute lymphoblastic leukemia is the most common pediatric cancer, its etiology remains poorly understood. In an attempt to replicate the …”
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Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease von Marie‐Gabrielle Duperron, Maria J. Knol, Quentin Le Grand, Tavia E Evans, Aniket Mishra, Gennady V. Roshchupkin, Takahiro Konuma, David Alexandre Tregouët, Jose Rafael Romero, Stefan Frenzel, Michelle Luciano, Edith Hofer, Mathieu Bourgey, Nicole D Dueker, Pilar Delgado, Saima Hilal, Rick M. Tankard, Florian Dubost, Jean Shin, Yasaman Saba, Christopher Chen, Tatjana Rundek, Alexander Teumer, Ami Tsuchida, Helena Schmidt, Perminder S. Sachdev, Wei Wen, Anne Joutel, Claudia L Satizabal, Ralph Sacco, Guillaume Bourque, Mark Lathrop, Tomas Paus, Israel Fernandez‐Cadenas, Bernard Mazoyer, Yukinori Okada, Hans J. Grabe, Karen A Mather, Reinhold Schmidt, M. Arfan Ikram, Christophe Tzourio, Joanna M Wardlaw, Sudha Seshadri, Hieab H.H. Adams, Stéphanie Debette

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Latency and interval therapy affect the evolution in metastatic colorectal cancer von Nikbakht, Hamid, Jessa, Selin, Sukhai, Mahadeo A., Arseneault, Madeleine, Zhang, Tong, Letourneau, Louis, Thomas, Mariam, Bourgey, Mathieu, Roehrl, Michael H. A., Eveleigh, Robert, Chen, Eric X., Krzyzanowska, Monika, Moore, Malcolm J., Giesler, Amanda, Yu, Celeste, Bedard, Philippe L., Kamel-Reid, Suzanne, Majewski, Jacek, Siu, Lillian L., Riazalhosseini, Yasser, Graham, Donna M.

“… While comparison of primary tumor and metastases has highlighted genomic heterogeneity in colorectal cancer (CRC), previous studies have focused on a single …”
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A cost-effective sequencing method for genetic studies combining high-depth whole exome and low-depth whole genome von Bhérer, Claude, Eveleigh, Robert, Trajanoska, Katerina, St-Cyr, Janick, Paccard, Antoine, Nadukkalam Ravindran, Praveen, Caron, Elizabeth, Bader Asbah, Nimara, McClelland, Peyton, Wei, Clare, Baumgartner, Iris, Schindewolf, Marc, Döring, Yvonne, Perley, Danielle, Lefebvre, François, Lepage, Pierre, Bourgey, Mathieu, Bourque, Guillaume, Ragoussis, Jiannis, Mooser, Vincent, Taliun, Daniel

“… Whole genome sequencing (WGS) at high-depth (30X) allows the accurate discovery of variants in the coding and non-coding DNA regions and helps elucidate the …”
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A Distributed Whole Genome Sequencing Benchmark Study von Corbett, Richard D., Eveleigh, Robert, Whitney, Joe, Barai, Namrata, Bourgey, Mathieu, Chuah, Eric, Johnson, Joanne, Moore, Richard A., Moradin, Neda, Mungall, Karen L., Pereira, Sergio, Reuter, Miriam S., Thiruvahindrapuram, Bhooma, Wintle, Richard F., Ragoussis, Jiannis, Strug, Lisa J., Herbrick, Jo-Anne, Aziz, Naveed, Jones, Steven J. M., Lathrop, Mark, Scherer, Stephen W., Staffa, Alfredo, Mungall, Andrew J.

“… Population sequencing often requires collaboration across a distributed network of sequencing centers for the timely processing of thousands of samples. In …”
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ALG: Automated Genotype Calling of Luminex Assays von Bourgey, Mathieu, Lariviere, Mathieu, Richer, Chantal, Sinnett, Daniel

“… Single nucleotide polymorphisms (SNPs) are the most commonly used polymorphic markers in genetics studies. Among the different platforms for SNP genotyping, …”
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Human T-bet Governs Innate and Innate-like Adaptive IFN-γ Immunity against Mycobacteria von Yang, Rui, Mele, Federico, Worley, Lisa, Langlais, David, Rosain, Jérémie, Benhsaien, Ibithal, Elarabi, Houda, Croft, Carys A, Doisne, Jean-Marc, Zhang, Peng, Weisshaar, Marc, Jarrossay, David, Latorre, Daniela, Shen, Yichao, Han, Jing, Ogishi, Masato, Gruber, Conor, Markle, Janet, Al Ali, Fatima, Rahman, Mahbuba, Khan, Taushif, Seeleuthner, Yoann, Kerner, Gaspard, Husquin, Lucas T, Maclsaac, Julia L, Jeljeli, Mohamed, Errami, Abderrahmane, Ailal, Fatima, Kobor, Michael S, Oleaga-Quintas, Carmen, Roynard, Manon, Bourgey, Mathieu, El Baghdadi, Jamila, Boisson-Dupuis, Stéphanie, Puel, Anne, Batteux, Fréderic, Rozenberg, Flore, Marr, Nico, Pan-Hammarström, Qiang, Bogunovic, Dusan, Quintana-Murci, Lluis, Carroll, Thomas, Ma, Cindy S, Abel, Laurent, Bousfiha, Aziz, Di Santo, James P, Glimcher, Laurie H, Gros, Philippe, Tangye, Stuart G, Sallusto, Federica, Bustamante, Jacinta, Casanova, Jean-Laurent

“… Inborn errors of human interferon gamma (IFN-γ) immunity underlie mycobacterial disease. We report a patient with mycobacterial disease due to inherited …”
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Whole Exome Sequencing Reveals the Major Genetic Contributors to Nonsyndromic Tetralogy of Fallot von Page, Donna J, Miossec, Matthieu J, Williams, Simon G, Monaghan, Richard M, Fotiou, Elisavet, Cordell, Heather J, Sutcliffe, Louise, Topf, Ana, Bourgey, Mathieu, Bourque, Guillaume, Eveleigh, Robert, Dunwoodie, Sally L, Winlaw, David S, Bhattacharya, Shoumo, Breckpot, Jeroen, Devriendt, Koenraad, Gewillig, Marc, Brook, J David, Setchfield, Kerry J, Bu'Lock, Frances A, O'Sullivan, John, Stuart, Graham, Bezzina, Connie R, Mulder, Barbara J M, Postma, Alex V, Bentham, James R, Baron, Martin, Bhaskar, Sanjeev S, Black, Graeme C, Newman, William G, Hentges, Kathryn E, Lathrop, G Mark, Santibanez-Koref, Mauro, Keavney, Bernard D

“… Familial recurrence studies provide strong evidence for a genetic component to the predisposition to sporadic, nonsyndromic Tetralogy of Fallot (TOF), the most …”
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Rare loss-of-function variants in type I IFN immunity genes are not associated with severe COVID-19 von Povysil, Gundula, Butler-Laporte, Guillaume, Shang, Ning, Wang, Chen, Khan, Atlas, Alaamery, Manal, Nakanishi, Tomoko, Zhou, Sirui, Forgetta, Vincenzo, Eveleigh, Robert J.M., Bourgey, Mathieu, Aziz, Naveed, Jones, Steven J.M., Knoppers, Bartha, Scherer, Stephen W., Strug, Lisa J., Lepage, Pierre, Ragoussis, Jiannis, Bourque, Guillaume, Alghamdi, Jahad, Aljawini, Nora, Albes, Nour, Al-Afghani, Hani M., Alghamdi, Bader, Almutairi, Mansour S., Mahmoud, Ebrahim Sabri, Abu-Safieh, Leen, El Bardisy, Hadeel, Harthi, Fawz S. Al, Alshareef, Abdulraheem, Suliman, Bandar Ali, Alqahtani, Saleh A., Almalik, Abdulaziz, Alrashed, May M., Massadeh, Salam, Mooser, Vincent, Lathrop, Mark, Fawzy, Mohamed, Arabi, Yaseen M., Mbarek, Hamdi, Saad, Chadi, Al-Muftah, Wadha, Jung, Junghyun, Mangul, Serghei, Badji, Radja, Thani, Asma Al, Ismail, Said I., Gharavi, Ali G., Abedalthagafi, Malak S., Richards, J. Brent, Goldstein, David B., Kiryluk, Krzysztof

“… A recent report found that rare predicted loss-of-function (pLOF) variants across 13 candidate genes in TLR3- and IRF-7 dependent type I IFN pathways explain …”
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GenPipes: an open-source framework for distributed and scalable genomic analyses von Bourgey, Mathieu, Dali, Rola, Eveleigh, Robert, Chen, Kuang Chung, Letourneau, Louis, Fillon, Joel, Michaud, Marc, Caron, Maxime, Sandoval, Johanna, Lefebvre, Francois, Leveque, Gary, Mercier, Eloi, Bujold, David, Marquis, Pascale, Van, Patrick Tran, Anderson de Lima Morais, David, Tremblay, Julien, Shao, Xiaojian, Henrion, Edouard, Gonzalez, Emmanuel, Quirion, Pierre-Olivier, Caron, Bryan, Bourque, Guillaume

“… NRC publication: Yes …”
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Legacy Data Confound Genomics Studies von Anderson-Trocmé, Luke, Farouni, Rick, Bourgey, Mathieu, Kamatani, Yoichiro, Higasa, Koichiro, Seo, Jeong-Sun, Kim, Changhoon, Matsuda, Fumihiko, Gravel, Simon

“… Recent reports have identified differences in the mutational spectra across human populations. Although some of these reports have been replicated in other …”
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Epigenetic and integrative cross-omics analyses of cerebral white matter hyperintensities on MRI von Yang, Yunju, Knol, Maria J, Wang, Ruiqi, Mishra, Aniket, Liu, Dan, Luciano, Michelle, Teumer, Alexander, Armstrong, Nicola, Bis, Joshua C, Jhun, Min A, Li, Shuo, Adams, Hieab H H, Aziz, Nasir Ahmad, Bastin, Mark E, Bourgey, Mathieu, Brody, Jennifer A, Frenzel, Stefan, Gottesman, Rebecca F, Hosten, Norbert, Hou, Lifang, Kardia, Sharon L R, Lohner, Valerie, Marquis, Pascale, Maniega, Susana Muñoz, Satizabal, Claudia L, Sorond, Farzaneh A, Valdés Hernández, Maria C, van Duijn, Cornelia M, Vernooij, Meike W, Wittfeld, Katharina, Yang, Qiong, Zhao, Wei, Boerwinkle, Eric, Levy, Daniel, Deary, Ian J, Jiang, Jiyang, Mather, Karen A, Mosley, Thomas H, Psaty, Bruce M, Sachdev, Perminder S, Smith, Jennifer A, Sotoodehnia, Nona, DeCarli, Charles S, Breteler, Monique M B, Ikram, M Arfan, Grabe, Hans J, Wardlaw, Joanna, Longstreth, W T, Launer, Lenore J, Seshadri, Sudha, Debette, Stephanie, Fornage, Myriam

“… Cerebral white matter hyperintensities on MRI are markers of cerebral small vessel disease, a major risk factor for dementia and stroke. Despite the successful …”
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RNA-Seq as a Tool to Study the Tumor Microenvironment von Panichnantakul, Pudchalaluck, Bourgey, Mathieu, Montpetit, Alexandre, Bourque, Guillaume, Riazalhosseini, Yasser

“… The transcriptome is composed of different types of RNA molecules including mRNAs, tRNAs, rRNAs, and other noncoding RNAs that are found inside a cell at a …”
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