Výsledky vyhľadávania - "Biomaterials"

Application of glutathione depletion in cancer therapy: Enhanced ROS-based therapy, ferroptosis, and chemotherapy Autor Niu, Boyi, Liao, Kaixin, Zhou, Yixian, Wen, Ting, Quan, Guilan, Pan, Xin, Wu, Chuanbin

“…Glutathione (GSH) is an important member of cellular antioxidative system. In cancer cells, a high level of GSH is indispensable to scavenge excessive reactive…”
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Promoting the healing of infected diabetic wound by an anti-bacterial and nano-enzyme-containing hydrogel with inflammation-suppressing, ROS-scavenging, oxygen and nitric oxide-generating properties Autor Tu, Chenxi, Lu, Huidan, Zhou, Tong, Zhang, Wanying, Deng, Liwen, Cao, Wangbei, Yang, Zhijian, Wang, Zhaolong, Wu, Xinyu, Ding, Jie, Xu, Feng, Gao, Changyou

“…The diabetic wound is easily to develop into a chronic wound because of the extremely serious and complex inflammatory microenvironment including biofilm…”
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ROS-scavenging hydrogel to promote healing of bacteria infected diabetic wounds Autor Zhao, He, Huang, Jie, Li, Yan, Lv, Xinjing, Zhou, Huiting, Wang, Hairong, Xu, Yunyun, Wang, Chao, Wang, Jian, Liu, Zhuang

“…Bacterial infection has been a great threat to dermal wounds, especially to difficult-to-heal diabetic wounds. It is known that reactive oxygen species (ROS)…”
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Progress in 3D bioprinting technology for tissue/organ regenerative engineering Autor Matai, Ishita, Kaur, Gurvinder, Seyedsalehi, Amir, McClinton, Aneesah, Laurencin, Cato T.

“…Escalating cases of organ shortage and donor scarcity worldwide are alarming reminders of the need for alternatives to allograft tissues. Within the last three…”
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Antibacterial adhesive injectable hydrogels with rapid self-healing, extensibility and compressibility as wound dressing for joints skin wound healing Autor Qu, Jin, Zhao, Xin, Liang, Yongping, Zhang, Tianlong, Ma, Peter X., Guo, Baolin

“…Designing wound dressing materials with outstanding therapeutic effects, self-healing, adhesiveness and suitable mechanical property has great practical…”
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M1 macrophage exosomes engineered to foster M1 polarization and target the IL-4 receptor inhibit tumor growth by reprogramming tumor-associated macrophages into M1-like macrophages Autor Gunassekaran, Gowri Rangaswamy, Poongkavithai Vadevoo, Sri Murugan, Baek, Moon-Chang, Lee, Byungheon

“…M2-polarized, pro-tumoral tumor-associated macrophages (TAMs) express the interleukin-4 receptor (IL4R) at higher levels compared with M1-polarized,…”
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Advances in nanomaterials for photodynamic therapy applications: Status and challenges Autor Chen, Jianming, Fan, Taojian, Xie, Zhongjian, Zeng, Qiqiao, Xue, Ping, Zheng, Tingting, Chen, Yun, Luo, Xiaoling, Zhang, Han

“…Photodynamic therapy (PDT), as a non-invasive therapeutic modality that is alternative to radiotherapy and chemotherapy, is extensively investigated for cancer…”
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Metal-organic frameworks for stimuli-responsive drug delivery Autor Wang, Ying, Yan, Jianhua, Wen, Nachuan, Xiong, Hongjie, Cai, Shundong, He, Qunye, Hu, Yaqin, Peng, Dongming, Liu, Zhenbao, Liu, Yanfei

“…Metal-organic framework (MOF), a novel hybrid porous material which is composited by metal ions and organic linkers, has drawn increasing attention and became…”
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A physicochemical double cross-linked multifunctional hydrogel for dynamic burn wound healing: shape adaptability, injectable self-healing property and enhanced adhesion Autor Yuan, Yang, Shen, Shihong, Fan, Daidi

“…Burn wounds are one of the most destructive skin traumas that cause more than 180000 deaths each year. Patients with large, irregular burn wounds suffer from…”
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Mesenchymal stem cell-macrophage crosstalk and bone healing Autor Pajarinen, Jukka, Lin, Tzuhua, Gibon, Emmanuel, Kohno, Yusuke, Maruyama, Masahiro, Nathan, Karthik, Lu, Laura, Yao, Zhenyu, Goodman, Stuart B.

“…Recent research has brought about a clear understanding that successful fracture healing is based on carefully coordinated cross-talk between inflammatory and…”
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Electrical stimulation and piezoelectric biomaterials for bone tissue engineering applications Autor Khare, Deepak, Basu, Bikramjit, Dubey, Ashutosh Kumar

“…Bioelectrical phenomenon in natural bone has been well recognized for its role in bone development and fracture healing. For example, the piezoelectricity…”
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Pancreatic cancer-targeting exosomes for enhancing immunotherapy and reprogramming tumor microenvironment Autor Zhou, Wenxi, Zhou, Yu, Chen, Xinli, Ning, Tingting, Chen, Hongyi, Guo, Qin, Zhang, Yiwen, Liu, Peixin, Zhang, Yujie, Li, Chao, Chu, Yongchao, Sun, Tao, Jiang, Chen

“…Immunotherapy has gained increasing focus in treating pancreatic ductal adenocarcinoma (PDAC), since conventional therapies like chemotherapy could not provide…”
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Bone regeneration strategies: Engineered scaffolds, bioactive molecules and stem cells current stage and future perspectives Autor Ho-Shui-Ling, Antalya, Bolander, Johanna, Rustom, Laurence E., Johnson, Amy Wagoner, Luyten, Frank P., Picart, Catherine

“…Bone fractures are the most common traumatic injuries in humans. The repair of bone fractures is a regenerative process that recapitulates many of the…”
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Microfluidic formulation of nanoparticles for biomedical applications Autor Shepherd, Sarah J., Issadore, David, Mitchell, Michael J.

“…Nanomedicine has made significant advances in clinical applications since the late-20th century, in part due to its distinct advantages in biocompatibility,…”
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Injectable Mussel‐Inspired highly adhesive hydrogel with exosomes for endogenous cell recruitment and cartilage defect regeneration Autor Zhang, Fang-Xue, Liu, Peng, Ding, Wang, Meng, Qing-Bing, Su, Di-Han, Zhang, Qi-Chen, Lian, Rui-Xian, Yu, Bao-Qing, Zhao, Ming-Dong, Dong, Jian, Li, Yu-Lin, Jiang, Li-Bo

“…In the early stage of osteoarthritis (OA), cartilage degradation in the surface region leads to superficial cartilage defect. However, enhancing the…”
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Nanomaterial-based blood-brain-barrier (BBB) crossing strategies Autor Xie, Jinbing, Shen, Zheyu, Anraku, Yasutaka, Kataoka, Kazunori, Chen, Xiaoyuan

“…Increasing attention has been paid to the diseases of central nervous system (CNS). The penetration efficiency of most CNS drugs into the brain parenchyma is…”
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Digital light processing 3D printed silk fibroin hydrogel for cartilage tissue engineering Autor Hong, Heesun, Seo, Ye Been, Kim, Do Yeon, Lee, Ji Seung, Lee, Young Jin, Lee, Hanna, Ajiteru, Olatunji, Sultan, Md Tipu, Lee, Ok Joo, Kim, Soon Hee, Park, Chan Hum

“…Three-dimensional printing with Digital Lighting Processing (DLP) printer has come into the new wave in the tissue engineering for regenerative medicine…”
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Exosome laden oxygen releasing antioxidant and antibacterial cryogel wound dressing OxOBand alleviate diabetic and infectious wound healing Autor Shiekh, Parvaiz A., Singh, Anamika, Kumar, Ashok

“…Lack of oxygen, reduced vascularization, elevated oxidative stress, and infection are critical clinical hallmarks of non-healing chronic diabetic wounds…”
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Antibacterial anti-oxidant electroactive injectable hydrogel as self-healing wound dressing with hemostasis and adhesiveness for cutaneous wound healing Autor Zhao, Xin, Wu, Hao, Guo, Baolin, Dong, Ruonan, Qiu, Yusheng, Ma, Peter X.

“…Injectable self-healing hydrogel dressing with multifunctional properties including anti-infection, anti-oxidative and conductivity promoting wound healing…”
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Surface functionalized exosomes as targeted drug delivery vehicles for cerebral ischemia therapy Autor Tian, Tian, Zhang, Hui-Xin, He, Chun-Peng, Fan, Song, Zhu, Yan-Liang, Qi, Cui, Huang, Ning-Ping, Xiao, Zhong-Dang, Lu, Zu-Hong, Tannous, Bakhos A., Gao, Jun

“…The safe and effective delivery of drugs is a major obstacle in the treatment of ischemic stroke. Exosomes hold great promise as an endogenous drug delivery…”
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