Suchergebnisse - "Bihl, Florian"

Differential boosting of innate and adaptive antiviral responses during pegylated-interferon-alpha therapy of chronic hepatitis B von Micco, Lorenzo, Peppa, Dimitra, Loggi, Elisabetta, Schurich, Anna, Jefferson, Lucy, Cursaro, Carmela, Panno, Arianna Martello, Bernardi, Mauro, Brander, Christian, Bihl, Florian, Andreone, Pietro, Maini, Mala K.

“… A better understanding of the immunomodulatory effects of PegIFNα therapy could allow more rational optimisation of future therapeutic approaches in chronic …”
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Virus-Specific Immune Response in HBeAg-Negative Chronic Hepatitis B: Relationship with Clinical Profile and HBsAg Serum Levels von Loggi, Elisabetta, Bihl, Florian K., Cursaro, Carmela, Granieri, Camilla, Galli, Silvia, Brodosi, Lucia, Furlini, Giuliano, Bernardi, Mauro, Brander, Christian, Andreone, Pietro

“… The immune impairment characterizing chronic hepatitis B (cHBV) infection is thought to be the consequence of persistent exposure to viral antigens. However, …”
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Modeling the Health and Economic Burden of Hepatitis C Virus in Switzerland von Müllhaupt, Beat, Bruggmann, Philip, Bihl, Florian, Blach, Sarah, Lavanchy, Daniel, Razavi, Homie, Semela, David, Negro, Francesco

“… Chronic hepatitis C virus infection is a major cause of liver disease in Switzerland and carries a significant cost burden. Currently, only conservative …”
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Progress toward implementing the Swiss Hepatitis Strategy: Is HCV elimination possible by 2030? von Müllhaupt, Beat, Bruggmann, Philip, Bihl, Florian, Blach, Sarah, Lavanchy, Daniel, Razavi, Homie, Robbins Scott, Sarah, Semela, David, Negro, Francesco

“… Catalyzed by the concerns over the growing public health and economic burden of Hepatitis C virus (HCV) in Switzerland, a diverse group of experts and patient …”
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Transfusion-transmitted infections von Bihl, Florian, Castelli, Damiano, Marincola, Francesco, Dodd, Roger Y, Brander, Christian

“… Although the risk of transfusion-transmitted infections today is lower than ever, the supply of safe blood products remains subject to contamination with known …”
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Liver transplantation from hepatitis B surface antigen positive donors: A safe way to expand the donor pool von Loggi, Elisabetta, Micco, Lorenzo, Ercolani, Giorgio, Cucchetti, Alessandro, Bihl, Florian K., Grazi, Gian Luca, Gitto, Stefano, Bontadini, Andrea, Bernardi, Mauro, Grossi, Paolo, Nanni Costa, Alessandro, Pinna, Antonio Daniele, Brander, Christian, Andreone, Pietro

“… The main limitation of orthotopic liver transplantation (OLT) is the scarcity of available donor organs. A possibility to increase the organ pool is to use …”
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Epidemiology of HEV Infection in Blood Donors in Southern Switzerland von Fontana, Stefano, Ripellino, Paolo, Niederhauser, Christoph, Widmer, Nadja, Gowland, Peter, Petrini, Orlando, Aprile, Manuela, Merlani, Giorgio, Bihl, Florian

“… From 2014 to 2016, the number of hepatitis E virus (HEV) infections in southern Switzerland increased dramatically and suggested food as a potential infection …”
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HIV Patients Developing Primary CNS Lymphoma Lack EBV-Specific CD4+ T Cell Function Irrespective of Absolute CD4+ T Cell Counts von Gasser, Olivier, Bihl, Florian K, Wolbers, Marcel, Loggi, Elisabetta, Steffen, Ingrid, Hirsch, Hans H, Günthard, Huldrych F, Walker, Bruce D, Brander, Christian, Battegay, Manuel, Hess, Christoph

“… In chronic HIV infection, antiretroviral therapy-induced normalization of CD4(+) T cell counts (immune reconstitution [IR]) is associated with a decreased …”
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Health-related quality of life outcomes after cholecystectomy von Carraro, Amedeo, Mazloum, Dania El, Bihl, Florian

“… Gallbladder diseases are very common in developed countries. Complicated gallstone disease represents the most frequent of biliary disorders for which surgery …”
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Host ethnicity and virus genotype shape the hepatitis B virus-specific T-cell repertoire von Tan, Anthony Tanoto, Loggi, Elisabetta, Boni, Carolina, Chia, Adeline, Gehring, Adam J, Sastry, Konduru S R, Goh, Vera, Fisicaro, Paola, Andreone, Pietro, Brander, Christian, Lim, Seng Gee, Ferrari, Carlo, Bihl, Florian, Bertoletti, Antonio

“… Repertoire composition, quantity, and qualitative functional ability are the parameters that define virus-specific T-cell responses and are linked with their …”
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Geoepidemiology of Primary Biliary Cholangitis: Lessons from Switzerland von Terziroli Beretta-Piccoli, Benedetta, Stirnimann, Guido, Cerny, Andreas, Semela, David, Hessler, Roxane, Helbling, Beat, Stickel, Felix, Kalid-de Bakker, Carolina, Bihl, Florian, Giostra, Emiliano, Filipowicz Sinnreich, Magdalena, Oneta, Carl, Baserga, Adriana, Invernizzi, Pietro, Carbone, Marco, Mertens, Joachim

“… No data on primary biliary cholangitis (PBC) are available in Switzerland. We established a national patient cohort to obtain information on PBC phenotypes and …”
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Impact of HLA-B alleles, epitope binding affinity, functional avidity, and viral coinfection on the immunodominance of virus-specific CTL responses von Bihl, Florian, Frahm, Nicole, Di Giammarino, Loriana, Sidney, John, John, Mina, Yusim, Karina, Woodberry, Tonia, Sango, Kaori, Hewitt, Hannah S, Henry, Leah, Linde, Caitlyn H, Chisholm, 3rd, John V, Zaman, Tauheed M, Pae, Eunice, Mallal, Simon, Walker, Bruce D, Sette, Alessandro, Korber, Bette T, Heckerman, David, Brander, Christian

“… Immunodominance is variably used to describe either the most frequently detectable response among tested individuals or the strongest response within a single …”
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Control of Raw Pork Liver Sausage Production Can Reduce the Prevalence of HEV Infection von Ripellino, Paolo, Pianezzi, Enea, Martinetti, Gladys, Zehnder, Cinzia, Mathis, Barbara, Giannini, Petra, Forrer, Nicola, Merlani, Giorgio, Dalton, Harry R., Petrini, Orlando, Bihl, Florian, Fontana, Stefano, Gobbi, Claudio

“… After an acute hepatitis E (HEV) outbreak in Southern Switzerland, in January 2017 the local public health authorities started an active program of food chain …”
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Birth cohort distribution and screening for viraemic hepatitis C virus infections in Switzerland von Bruggmann, Philip, Negro, Francesco, Bihl, Florian, Blach, Sarah, Lavanchy, Daniel, Müllhaupt, Beat, Razavi, Homie, Semela, David

“… OBJECTIVE: In Switzerland, fewer than 40% of hepatitis C virus (HCV) infected individuals have been diagnosed. The aim of this project was to analyse the …”
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Anticoagulant therapy for nodular regenerative hyperplasia in a HIV-infected patient von Bihl, Florian, Janssens, Filip, Boehlen, Francoise, Rubbia-Brandt, Laura, Hadengue, Antoine, Spahr, Laurent

“… Background Nodular regenerative hyperplasia (NRH) has been recently recognized as an emergent cause of liver disease in HIV-infected patients. NRH may cause …”
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Lytic and latent antigens of the human gammaherpesviruses Kaposi's sarcoma-associated herpesvirus and Epstein-Barr virus induce T-cell responses with similar functional properties and memory phenotypes von Bihl, Florian, Narayan, Murli, Chisholm, 3rd, John V, Henry, Leah M, Suscovich, Todd J, Brown, Elizabeth E, Welzel, Tania M, Kaufmann, Daniel E, Zaman, Tauheed M, Dollard, Sheila, Martin, Jeff N, Wang, Fred, Scadden, David T, Kaye, Kenneth M, Brander, Christian

“… The cellular immunity against Kaposi's sarcoma-associated herpesvirus (KSHV) is poorly characterized and has not been compared to T-cell responses against …”
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Simultaneous assessment of cytotoxic T lymphocyte responses against multiple viral infections by combined usage of optimal epitope matrices, anti- CD3 mAb T-cell expansion and "RecycleSpot" von Bihl, Florian K, Loggi, Elisabetta, Chisholm, John V, Hewitt, Hannah S, Henry, Leah M, Linde, Caitlyn, Suscovich, Todd J, Wong, Johnson T, Frahm, Nicole, Andreone, Pietro, Brander, Christian

“… The assessment of cellular anti-viral immunity is often hampered by the limited availability of adequate samples, especially when attempting simultaneous, …”
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Targets of emerging therapies for viral hepatitis B and C von Yerly, Daniel, Di Giammarino, Loriana, Bihl, Florian, Cerny, Andreas

“… Viral hepatitis B and C, structurally two completely different viruses, commonly infect human hepatocytes and cause similar clinical manifestations. Since …”
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Hyperimmune anti-HBs plasma as alternative to commercial immunoglobulins for prevention of HBV recurrence after liver transplantation von Bihl, Florian, Russmann, Stefan, Gurtner, Vanina, Di Giammarino, Loriana, Pizzi-Bosman, Loredana, Michel, Martine, Cerny, Andreas, Hadengue, Antoine, Majno, Pietro, Giostra, Emiliano, Castelli, Damiano, Mentha, Gilles

“… Background Hepatitis B immune globulins (HBIG) in combination with nucleos(t)ide analogues (NA) are effectively used for the prevention of hepatitis B virus …”
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Discovery and characterization of highly immunogenic and broadly recognized mimics of the HIV‐1 CTL epitope Gag77–85 von Boggiano, César, Moya, Rosa, Pinilla, Clemencia, Bihl, Florian, Brander, Christian, Sidney, John, Sette, Alessandro, Blondelle, Sylvie E.

“… Human immunodeficiency virus (HIV)‐specific cytotoxic T lymphocytes (CTL) play an important role in HIV infection. Given the viral genetic diversity, the …”
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