Suchergebnisse - "Bezerra, Marcos André C"

DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease von Lettre, Guillaume, Sankaran, Vijay G, Bezerra, Marcos André C, Araújo, Aderson S, Uda, Manuela, Sanna, Serena, Cao, Antonio, Schlessinger, David, Costa, Fernando F, Hirschhorn, Joel N, Orkin, Stuart H

“… Sickle cell disease (SCD) is a debilitating monogenic blood disorder with a highly variable phenotype characterized by severe pain crises, acute clinical …”
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BMP6 and VDR gene polymorphisms are associated with osteonecrosis in a sickle cell anaemia cohort von Arcanjo, Gabriela S., Souza, Mariana B., Domingos, Igor F., Pereira‐Martins, Diego A., Falcão, Diego A., Batista, Jessica V., Hatzlhofer, Betania L., Diniz, Madi V., Silva, Alexsandro P., Guaraná, Werbson L., Hazin, Manuela F., Araujo, Aderson S., Cunha, Anderson F., Saad, Sara O., Costa, Fernando F., Lucena‐Araujo, Antonio R., Bezerra, Marcos André C.

“… Summary The occurrence and severity of osteonecrosis in sickle cell anaemia (SCA) vary due to risk factors, including genetic modifiers. Bone morphogenetic …”
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Global gene expression reveals an increase of HMGB1 and APEX1 proteins and their involvement in oxidative stress, apoptosis and inflammation pathways among beta‐thalassaemia intermedia and major phenotypes von Maia de Oliveira da Silva, João Pedro, Brugnerotto, Ana Flávia, S. Romanello, Karen, K. L. Teixeira, Karina, Lanaro, Carolina, S. Duarte, Adriana, G. L. Costa, Gustavo, da Silva Araújo, Aderson, C. Bezerra, Marcos André, de Farias Domingos, Igor, Pereira Martins, Diego A., Malavazi, Iran, F. Costa, Fernando, Cunha, Anderson F.

“… Summary Beta‐thalassaemia (BT) is classified according to blood transfusion requirement as minor (BTMi), intermedia (BTI) and major (BTM). BTM is the most …”
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Neutrophil extracellular trap regulators in sickle cell disease: Modulation of gene expression of PADI4, neutrophil elastase, and myeloperoxidase during vaso‐occlusive crisis von Hounkpe, Bidossessi Wilfried, Chenou, Francine, Domingos, Igor de Farias, Cardoso, Evilazio Cunha, Costa Sobreira, Marcondes José de Vasconcelos, Araujo, Aderson S., Lucena‐Araújo, Antonio Roberto, da Silva Neto, Pedro Vieira, Malheiro, Adriana, Fraiji, Nelson Abrahim, Costa, Fernando Ferreira, Bezerra, Marcos André C., Santos, Magnun Nueldo Nunes, De Paula, Erich Vinicius

“… Recent evidence suggests that generation of neutrophil extracellular traps (NETosis), one of the components of immunothrombosis, is associated with the …”
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Global analysis of erythroid cells redox status reveals the involvement of Prdx1 and Prdx2 in the severity of beta thalassemia von Romanello, Karen S., Teixeira, Karina K. L., Silva, João Pedro M. O., Nagamatsu, Sheila T., Bezerra, Marcos André C., Domingos, Igor F., Martins, Diego A. P., Araujo, Aderson S., Lanaro, Carolina, Breyer, Carlos A., Ferreira, Regiane A., Franco-Penteado, Carla, Costa, Fernando F., Malavazi, Iran, Netto, Luis E. S., de Oliveira, Marcos A., Cunha, Anderson F.

“… β-thalassemia is a worldwide distributed monogenic red cell disorder, characterized by an absent or reduced beta globin chain synthesis. The unbalance of …”
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Women with TT genotype for eNOS gene are more responsive in lowering blood pressure in response to exercise von Sponton, Carlos H G, Rezende, Tiago M, Mallagrino, Pamella A, Franco-Penteado, Carla F, Bezerra, Marcos André C, Zanesco, Angelina

“… The aim of this study was to investigate whether -786T>C endothelial nitric oxide synthase (eNOS) gene polymorphism might influence the effect of long-term …”
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MTHFR polymorphic variant C677T is associated to vascular complications in sickle-cell disease von Hatzlhofer, Betânia L D, Bezerra, Marcos André C, Santos, Magnun N N, Albuquerque, Dulcinéia M, Freitas, Elizabete M, Costa, Fernando F, Araújo, Aderson S, Muniz, Maria Tereza C

“… Vaso-occlusion is a determinant for most signs and symptoms of sickle-cell anemia (SCA). The mechanisms involved in the pathogenesis of vascular complications …”
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Molecular Variations Linked to the Grouping of β- and α-Globin Genes in Neonatal Patients with Sickle Cell Disease in the State of Pernambuco, Brazil von Bezerra, Marcos André C., Santos, Magnun N.N., Araújo, Aderson S., Gomes, Yara M., Abath, Frederico G.C., Bandeira, Flavia M.G.C.

“… Various factors have been described as phenotypic modulators of sickle cell disease, such as levels of fetal hemoglobin (Hb F), presence of α-thalassemia …”
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Follow-up of children with hemoglobinopathies diagnosed by the Brazilian Neonatal Screening Program in the State of Pernambuco von Soares, Ana Caroline Novaes, Samico, Isabella Chagas, Araújo, Aderson Silva, Bezerra, Marcos André C., Hatzlhofer, Betânia Lucena Domingues

“… To determine the geographical distribution of hemoglobinopathies in the State of Pernambuco, to characterize the children with these diseases and to describe …”
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Family screening for HBBS gene and detection of new cases of sickle cell trait in Northeastern Brazil von Bandeira, Flavia Miranda Gomes C, Santos, Magnun Nueldo Nunes, Bezerra, Marcos André M, Gomes, Yara M, Araujo, Aderson Silva, Braga, Maria Cynthia, Souza, Wayner Vieira, Abath, Frederico G C

“… To estimate the additional number of affected individuals based on the prevalence of sickle-cell syndromes among relatives of index cases. Cross-sectional …”
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Prevalence of dyslipidemia in middle-aged adults with NOS3 gene polymorphism and low cardiorespiratory fitness von Malagrino, Pamella A, Sponton, Carlos H G, Esposti, Rodrigo D, Franco-Penteado, Carla F, Fernandes, Romulo A, Bezerra, Marcos André C, Albuquerque, Dulcinéia M, Rodovalho, Cynara M, Bacci, Maurício, Zanesco, Angelina

“… To evaluate the influence of the interaction between endothelial nitric oxide synthase gene (NOS3) polymorphisms at positions -786T>C, Glu298Asp and intron …”
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