Suchergebnisse - "Berti, Matteo"

The plasticity of DNA replication forks in response to clinically relevant genotoxic stress von Berti, Matteo, Cortez, David, Lopes, Massimo

“… Complete and accurate DNA replication requires the progression of replication forks through DNA damage, actively transcribed regions, structured DNA and …”
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Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells von Zellweger, Ralph, Dalcher, Damian, Mutreja, Karun, Berti, Matteo, Schmid, Jonas A, Herrador, Raquel, Vindigni, Alessandro, Lopes, Massimo

“… Replication fork reversal protects forks from breakage after poisoning of Topoisomerase 1. We here investigated fork progression and chromosomal breakage in …”
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Replication fork reversal triggers fork degradation in BRCA2-defective cells von Mijic, Sofija, Zellweger, Ralph, Chappidi, Nagaraja, Berti, Matteo, Jacobs, Kurt, Mutreja, Karun, Ursich, Sebastian, Ray Chaudhuri, Arnab, Nussenzweig, Andre, Janscak, Pavel, Lopes, Massimo

“… Besides its role in homologous recombination, the tumor suppressor BRCA2 protects stalled replication forks from nucleolytic degradation. Defective fork …”
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Sequential role of RAD51 paralog complexes in replication fork remodeling and restart von Berti, Matteo, Teloni, Federico, Mijic, Sofija, Ursich, Sebastian, Fuchs, Jevgenij, Palumbieri, Maria Dilia, Krietsch, Jana, Schmid, Jonas A., Garcin, Edwige B., Gon, Stéphanie, Modesti, Mauro, Altmeyer, Matthias, Lopes, Massimo

“… Homologous recombination (HR) factors were recently implicated in DNA replication fork remodeling and protection. While maintaining genome stability, …”
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Runoff‐generated debris flows: Observation of initiation conditions and erosion–deposition dynamics along the channel at Cancia (eastern Italian Alps) von Simoni, Alessandro, Bernard, Martino, Berti, Matteo, Boreggio, Mauro, Lanzoni, Stefano, Stancanelli, Laura Maria, Gregoretti, Carlo

“… In the Dolomitic region, abundant coarse hillslope sediment is commonly found at the toe of rocky cliffs. Ephemeral channels originate where lower permeability …”
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The perfect debris flow? Aggregated results from 28 large-scale experiments von Iverson, Richard M., Logan, Matthew, LaHusen, Richard G., Berti, Matteo

“… Aggregation of data collected in 28 controlled experiments reveals reproducible debris‐flow behavior that provides a clear target for model tests. In each …”
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Debris-flow monitoring and warning: Review and examples von Hürlimann, Marcel, Coviello, Velio, Bel, Coraline, Guo, Xiaojun, Berti, Matteo, Graf, Christoph, Hübl, Johannes, Miyata, Shusuke, Smith, Joel B., Yin, Hsiao-Yuan

“… Debris flows represent one of the most dangerous types of mass movements, because of their high velocities, large impact forces and long runout distances. This …”
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Landslide prediction, monitoring and early warning: a concise review of state-of-the-art von Chae, Byung-Gon, Park, Hyuck-Jin, Catani, Filippo, Simoni, Alessandro, Berti, Matteo

“… Landslide is one of the repeated geological hazards during rainy season, which causes fatalities, damage to property and economic losses in Korea. Landslides …”
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DNA2 drives processing and restart of reversed replication forks in human cells von Thangavel, Saravanabhavan, Berti, Matteo, Levikova, Maryna, Pinto, Cosimo, Gomathinayagam, Shivasankari, Vujanovic, Marko, Zellweger, Ralph, Moore, Hayley, Lee, Eu Han, Hendrickson, Eric A, Cejka, Petr, Stewart, Sheila, Lopes, Massimo, Vindigni, Alessandro

“… Accurate processing of stalled or damaged DNA replication forks is paramount to genomic integrity and recent work points to replication fork reversal and …”
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The influence of preferential flow on pressure propagation and landslide triggering of the Rocca Pitigliana landslide von Shao, Wei, Bogaard, Thom, Bakker, Mark, Berti, Matteo

“… •The influence of preferential flow on pressure propagation and slope stability is investigated with a 1D dual-permeability model coupled with an …”
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Rainfall‐Runoff Modeling in Rocky Headwater Catchments for the Prediction of Debris Flow Occurrence von Bernard, Martino, Barbini, Matteo, Berti, Matteo, Boreggio, Mauro, Simoni, Alessandro, Gregoretti, Carlo

“… In the Dolomites, steep rocky cliffs are marked by numerous narrow gullies. When high‐intensity short‐duration precipitation occurs, these gullies concentrate …”
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ATR-Mediated Global Fork Slowing and Reversal Assist Fork Traverse and Prevent Chromosomal Breakage at DNA Interstrand Cross-Links von Mutreja, Karun, Krietsch, Jana, Hess, Jeannine, Ursich, Sebastian, Berti, Matteo, Roessler, Fabienne K., Zellweger, Ralph, Patra, Malay, Gasser, Gilles, Lopes, Massimo

“… Interstrand cross-links (ICLs) are toxic DNA lesions interfering with DNA metabolism that are induced by widely used anticancer drugs. They have long been …”
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Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition von Berti, Matteo, Ray Chaudhuri, Arnab, Thangavel, Saravanabhavan, Gomathinayagam, Shivasankari, Kenig, Sasa, Vujanovic, Marko, Odreman, Federico, Glatter, Timo, Graziano, Simona, Mendoza-Maldonado, Ramiro, Marino, Francesca, Lucic, Bojana, Biasin, Valentina, Gstaiger, Matthias, Aebersold, Ruedi, Sidorova, Julia M, Monnat, Raymond J, Lopes, Massimo, Vindigni, Alessandro

“… The cytotoxic effects of topoisomerase I inhibitors such as camptothecin can be modulated by replication fork reversal, in a process that requires …”
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Application of hydrological model simulations in landslide predictions von Zhao, Binru, Dai, Qiang, Han, Dawei, Zhang, Jun, Zhuo, Lu, Berti, Matteo

“… The importance of soil moisture conditions in the initiation of landslides has been widely recognized. This study takes advantage of the distributed …”
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Evaluation of Remotely Sensed Soil Moisture for Landslide Hazard Assessment von Zhuo, Lu, Dai, Qiang, Han, Dawei, Chen, Ningsheng, Zhao, Binru, Berti, Matteo

“… Soil moisture is important in the triggering of many types of landslides. However, in situ soil moisture data are rarely available in hazardous zones. The …”
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Field evidence of pore pressure diffusion in clayey soils prone to landsliding von Berti, Matteo, Simoni, Alessandro

“… The hydrologic behavior of shallow weathered soils commonly determines the propensity for slope failure. Here we use laboratory data and field data collected …”
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Observation and analysis of near-surface pore-pressure measurements in clay-shales slopes von Berti, Matteo, Simoni, Alessandro

“… Clay‐shales largely outcrop in the Northern Apennines of Italy, where they are associated with frequent and widespread landslide activity. The paper presents …”
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Threshold Definition for Monitoring Gapa Landslide under Large Variations in Reservoir Level Using GNSS von Wu, Shuangshuang, Hu, Xinli, Zheng, Wenbo, Berti, Matteo, Qiao, Zhitian, Shen, Wei

“… The triggering threshold is one of the most important parameters for landslide early warning systems (EWSs) at the slope scale. In the present work, a velocity …”
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MAMODIS - A low-cost monitoring system for debris flows based on infrasound and seismic signals von Schimmel, Andreas, Berti, Matteo

“… The automatic detection of sediment related disasters like landslides, debris flows and debris floods, gets increasing importance for hazard mitigation and …”
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Surface-wave velocity measurements of shear stiffness of moving earthflows von Berti, Matteo, Bertello, Lara, Squarzoni, Gabriela

“… Earthflows are a flow-like movement of plastic clayey soils characterized by long periods of slow motion (at rates averaging a few meters per year or less) …”
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