Search Results - "Bakshi, Rohit"

COVID-19 mRNA vaccination leading to CNS inflammation: a case series by Khayat-Khoei, Mahsa, Bhattacharyya, Shamik, Katz, Joshua, Harrison, Daniel, Tauhid, Shahamat, Bruso, Penny, Houtchens, Maria K., Edwards, Keith R., Bakshi, Rohit

“…The availability of vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), provides hope towards mitigation of the coronavirus…”
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Gut Microbiome in Progressive Multiple Sclerosis by Cox, Laura M., Maghzi, Amir Hadi, Liu, Shirong, Tankou, Stephanie K., Dhang, Fyonn H., Willocq, Valerie, Song, Anya, Wasén, Caroline, Tauhid, Shahamat, Chu, Renxin, Anderson, Mark C., De Jager, Philip L., Polgar‐Turcsanyi, Mariann, Healy, Brian C., Glanz, Bonnie I., Bakshi, Rohit, Chitnis, Tanuja, Weiner, Howard L.

“…Objective This study was undertaken to investigate the gut microbiome in progressive multiple sclerosis (MS) and how it relates to clinical disease. Methods We…”
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The neutrophil-to-lymphocyte and monocyte-to-lymphocyte ratios are independently associated with neurological disability and brain atrophy in multiple sclerosis by Hemond, Christopher C., Glanz, Bonnie I., Bakshi, Rohit, Chitnis, Tanuja, Healy, Brian C.

“…Background Serum hematological indices such as the neutrophil-lymphocyte ratio (NLR) or monocyte-lymphocyte ratio (MLR) have been used as biomarkers of…”
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Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation by Mayo, Lior, Trauger, Sunia A, Blain, Manon, Nadeau, Meghan, Patel, Bonny, Alvarez, Jorge I, Mascanfroni, Ivan D, Yeste, Ada, Kivisäkk, Pia, Kallas, Keith, Ellezam, Benjamin, Bakshi, Rohit, Prat, Alexandre, Antel, Jack P, Weiner, Howard L, Quintana, Francisco J

“…In multiple sclerosis and experimental autoimmune encephalomyelitis, astrocytes produce lactosylceramide, a glycolipid that promotes astrocyte and microglial…”
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7T MRI cerebral leptomeningeal enhancement is common in relapsing-remitting multiple sclerosis and is associated with cortical and thalamic lesions by Zurawski, Jonathan, Tauhid, Shahamat, Chu, Renxin, Khalid, Fariha, Healy, Brian C, Weiner, Howard L, Bakshi, Rohit

“…Meningeal inflammation may contribute to gray matter (GM) involvement in multiple sclerosis (MS) and is proposed to manifest as magnetic resonance imaging…”
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Exploration of machine learning techniques in predicting multiple sclerosis disease course by Zhao, Yijun, Healy, Brian C., Rotstein, Dalia, Guttmann, Charles R. G., Bakshi, Rohit, Weiner, Howard L., Brodley, Carla E., Chitnis, Tanuja

“…To explore the value of machine learning methods for predicting multiple sclerosis disease course. 1693 CLIMB study patients were classified as increased…”
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The measurement and clinical relevance of brain atrophy in multiple sclerosis by Bermel, Robert A, Bakshi, Rohit

“…Brain atrophy has emerged as a clinically relevant component of disease progression in multiple sclerosis. Progressive loss of brain tissue bulk can be…”
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FABP7 is increased in progressive multiple sclerosis and induces a pro-inflammatory phenotype in monocytes through a glycolytic switch by Patel, Rohit, King, Devin, LaBarre, Brenna, Lokhande, Hrishikesh, Caefer, Danielle, Varghese, Johnna F., Warner, Keturah, Bouffard, Marc A., Saxena, Shrishti, Zhirova, Alena, Bakshi, Rohit, Chitnis, Tanuja

“…Multiple sclerosis (MS) involves dysregulation of innate immune cells including monocytes, especially in progressive MS. Fatty acid binding proteins (FABP) are…”
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Spatial distribution of multiple sclerosis lesions in the cervical spinal cord by Eden, Dominique, Gros, Charley, Badji, Atef, Dupont, Sara M, De Leener, Benjamin, Maranzano, Josefina, Zhuoquiong, Ren, Liu, Yaou, Granberg, Tobias, Ouellette, Russell, Stawiarz, Leszek, Hillert, Jan, Talbott, Jason, Bannier, Elise, Kerbrat, Anne, Edan, Gilles, Labauge, Pierre, Callot, Virginie, Pelletier, Jean, Audoin, Bertrand, Rasoanandrianina, Henitsoa, Brisset, Jean-Christophe, Valsasina, Paola, Rocca, Maria A, Filippi, Massimo, Bakshi, Rohit, Tauhid, Shahamat, Prados, Ferran, Yiannakas, Marios, Kearney, Hugh, Ciccarelli, Olga, Smith, Seth A, Andrada Treaba, Constantina, Mainero, Caterina, Lefeuvre, Jennifer, Reich, Daniel S, Nair, Govind, Shepherd, Timothy M, Charlson, Erik, Tachibana, Yasuhiko, Hori, Masaaki, Kamiya, Kouhei, Chougar, Lydia, Narayanan, Sridar, Cohen-Adad, Julien

“…Spinal cord lesions detected on MRI hold important diagnostic and prognostic value for multiple sclerosis. Previous attempts to correlate lesion burden with…”
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Automated segmentation of cerebral deep gray matter from MRI scans: effect of field strength on sensitivity and reliability by Chu, Renxin, Hurwitz, Shelley, Tauhid, Shahamat, Bakshi, Rohit

“…Background The cerebral subcortical deep gray matter nuclei (DGM) are a common, early, and clinically-relevant site of atrophy in multiple sclerosis (MS)…”
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Serum NfL but not GFAP predicts cognitive decline in active progressive multiple sclerosis patients by Barro, Christian, Healy, Brian C, Saxena, Shrishti, Glanz, Bonnie I, Paul, Anu, Polgar-Turcsanyi, Mariann, Guttmann, Charles Rg, Bakshi, Rohit, Weiner, Howard L, Chitnis, Tanuja

“…Cognitive decline is inadequately captured by the standard neurological examination. Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein…”
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Accuracy of serum neurofilament light to identify contrast-enhancing lesions in multiple sclerosis by Bose, Gauruv, Healy, Brian C, Barro, Christian, Moreira Ferreira, Vanessa F, Saxena, Shrishti, Glanz, Bonnie I, Lokhande, Hrishikesh A, Polgar-Turcsanyi, Mariann, Bakshi, Rohit, Weiner, Howard L, Chitnis, Tanuja

“…Contrast-enhancing magnetic resonance imaging (MRI) lesions (CELs) indicate acute multiple sclerosis inflammation. Serum biomarkers, neurofilament light…”
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Ensemble learning predicts multiple sclerosis disease course in the SUMMIT study by Zhao, Yijun, Wang, Tong, Bove, Riley, Cree, Bruce, Henry, Roland, Lokhande, Hrishikesh, Polgar-Turcsanyi, Mariann, Anderson, Mark, Bakshi, Rohit, Weiner, Howard L., Chitnis, Tanuja

“…The rate of disability accumulation varies across multiple sclerosis (MS) patients. Machine learning techniques may offer more powerful means to predict…”
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Rapid semi-automatic segmentation of the spinal cord from magnetic resonance images: Application in multiple sclerosis by Horsfield, Mark A., Sala, Stefania, Neema, Mohit, Absinta, Martina, Bakshi, Anshika, Sormani, Maria Pia, Rocca, Maria A., Bakshi, Rohit, Filippi, Massimo

“…A new semi-automatic method for segmenting the spinal cord from MR images is presented. The method is based on an active surface (AS) model of the cord…”
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Novel serum biomarker associations with 7 Tesla MRI-defined cortical lesions, leptomeningeal enhancement, and deep gray matter volume in early multiple sclerosis by Miclea, Andrei, Zurawski, Jonathan, Healy, Brian C., Saxena, Shrishti, Lokhande, Hrishikesh, Quattrucci, Molly, Chu, Renxin, Weiner, Howard L., Bakshi, Rohit, Chitnis, Tanuja

“…Gray matter demyelinating lesions, brain atrophy and meningeal inflammation are hypothesized to be relevant in multiple sclerosis (MS) disease pathogenesis,…”
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Whole brain and deep gray matter atrophy detection over 5 years with 3T MRI in multiple sclerosis using a variety of automated segmentation pipelines by Chu, Renxin, Kim, Gloria, Tauhid, Shahamat, Khalid, Fariha, Healy, Brian C., Bakshi, Rohit

“…Cerebral atrophy is common in multiple sclerosis (MS) and selectively involves gray matter (GM). Several fully automated methods are available to measure whole…”
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PARE: A framework for removal of confounding effects from any distance-based dimension reduction method by Chen, Andrew A., Clark, Kelly, Dewey, Blake E., DuVal, Anna, Pellegrini, Nicole, Nair, Govind, Jalkh, Youmna, Khalil, Samar, Zurawski, Jon, Calabresi, Peter A., Reich, Daniel S., Bakshi, Rohit, Shou, Haochang, Shinohara, Russell T.

“…Dimension reduction tools preserving similarity and graph structure such as t -SNE and UMAP can capture complex biological patterns in high-dimensional data…”
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Automatic spinal cord localization, robust to MRI contrasts using global curve optimization by Gros, Charley, De Leener, Benjamin, Dupont, Sara M., Martin, Allan R., Fehlings, Michael G., Bakshi, Rohit, Tummala, Subhash, Auclair, Vincent, McLaren, Donald G., Callot, Virginie, Cohen-Adad, Julien, Sdika, Michaël

“…•Automatic, fast and robust method to detect the center of the spinal cord on MRI data.•Machine learning based method followed by a global curve…”
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Iron in Chronic Brain Disorders: Imaging and Neurotherapeutic Implications by Stankiewicz, James, Panter, S. Scott, Neema, Mohit, Arora, Ashish, Batt, Courtney E., Bakshi, Rohit

“…Iron is important for brain oxygen transport, electron transfer, neurotransmitter synthesis, and myelin production. Though iron deposition has been observed in…”
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Trajectories of Symbol Digit Modalities Test performance in individuals with multiple sclerosis by Healy, Brian C, Barker, Lindsay, Bakshi, Rohit, Benedict, Ralph H B, Gonzalez, Cindy T, Chitnis, Tanuja, Weiner, Howard L, Glanz, Bonnie I

“…Although cognitive problems have been identified in people with multiple sclerosis (PwMS), few studies have investigated the long-term change in cognitive…”
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