Suchergebnisse - "Aziz, N. Ahmad"

Genetic Variants in Sulfonylurea Targets Affect Parkinson's Disease Risk: A Two‐Sample Mendelian Randomization Study von Aziz, N. Ahmad, Wüllner, Ullrich

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Life Course Adiposity and Amyotrophic Lateral Sclerosis: A Mendelian Randomization Study von Aziz, N. Ahmad

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Seroprevalence and correlates of SARS-CoV-2 neutralizing antibodies from a population-based study in Bonn, Germany von Aziz, N. Ahmad, Corman, Victor M., Echterhoff, Antje K. C., Müller, Marcel A., Richter, Anja, Schmandke, Antonio, Schmidt, Marie Luisa, Schmidt, Thomas H., de Vries, Folgerdiena M., Drosten, Christian, Breteler, Monique M. B.

“… To estimate the seroprevalence and temporal course of SARS-CoV-2 neutralizing antibodies, we embedded a multi-tiered seroprevalence survey within an ongoing …”
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Insulin resistance accounts for metabolic syndrome‐related alterations in brain structure von Lu, Ran, Aziz, N. Ahmad, Diers, Kersten, Stöcker, Tony, Reuter, Martin, Breteler, Monique M.B.

“… Metabolic syndrome (MetS) is a major public health burden worldwide and associated with brain abnormalities. Although insulin resistance is considered a …”
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Visual impairment and retinal and brain neurodegeneration: A population‐based study von Garzone, Davide, Finger, Robert P., Mauschitz, Matthias M., Koch, Alexandra, Reuter, Martin, Breteler, Monique M. B., Aziz, N. Ahmad

“… Visual impairment and retinal neurodegeneration are intrinsically connected and both have been associated with cognitive impairment and brain atrophy, but the …”
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Statin use and delayed onset of Huntington's disease von Aziz, N. Ahmad

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The lipidomic correlates of epigenetic aging across the adult lifespan: A population‐based study von Liu, Dan, Aziz, N. Ahmad, Landstra, Elvire Nadieh, Breteler, Monique M. B.

“… Lipid signaling is involved in longevity regulation, but which specific lipid molecular species affect human biological aging remains largely unknown. We …”
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Genome-wide associations of aortic distensibility suggest causality for aortic aneurysms and brain white matter hyperintensities von Francis, Catherine M., Futschik, Matthias E., Huang, Jian, Bai, Wenjia, Sargurupremraj, Muralidharan, Teumer, Alexander, Breteler, Monique M. B., Petretto, Enrico, Ho, Amanda S. R., Amouyel, Philippe, Engelter, Stefan T., Bülow, Robin, Völker, Uwe, Völzke, Henry, Dörr, Marcus, Imtiaz, Mohammed-Aslam, Aziz, N. Ahmad, Lohner, Valerie, Ware, James S., Debette, Stephanie, Elliott, Paul, Dehghan, Abbas, Matthews, Paul M.

“… Aortic dimensions and distensibility are key risk factors for aortic aneurysms and dissections, as well as for other cardiovascular and cerebrovascular …”
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Telomere length as a modifier of age-at-onset in Huntington disease: a two-sample Mendelian randomization study von Aziz, N. Ahmad, Weydt, Patrick

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Overlap between age-at-onset and disease-progression determinants in Huntington disease von Aziz, N Ahmad, van der Burg, Jorien M M, Tabrizi, Sarah J, Landwehrmeyer, G Bernhard

“… A fundamental but still unresolved issue regarding Huntington disease (HD) pathogenesis is whether the factors that determine age at onset are the same as …”
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Single cell whole-genome sequencing of brain cells: age- and cell-type specific mutational profiles von Capasso, Melania, Aziz, N. Ahmad

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Insulin Sensitivity in De Novo Parkinson's Disease: A Hyperinsulinemic‐Euglycemic Clamp Study von Aziz, N. Ahmad, Roos, Raymund A.C., Pijl, Hanno

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Polygenic risk scores for schizophrenia are associated with oculomotor endophenotypes von Coors, Annabell, Imtiaz, Mohammed-Aslam, Boenniger, Meta M., Aziz, N. Ahmad, Breteler, Monique M. B., Ettinger, Ulrich

“… Schizophrenia is a heterogeneous disorder with substantial heritability. The use of endophenotypes may help clarify its aetiology. Measures from the smooth …”
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Genome-wide association meta-analysis of human olfactory identification discovers sex-specific and sex-differential genetic variants von Förster, Franz, Emmert, David, Horn, Katrin, Pott, Janne, Frasnelli, Johannes, Imtiaz, Mohammed Aslam, Melas, Konstantinos, Talevi, Valentina, Chen, Honglei, Engel, Christoph, Filosi, Michele, Fornage, Myriam, Gögele, Martin, Löffler, Markus, Mosley, Thomas H., Pattaro, Cristian, Pramstaller, Peter, Shrestha, Srishti, Aziz, N. Ahmad, Breteler, Monique M. B., Wirkner, Kerstin, Scholz, Markus, Fuchsberger, Christian

“… Smelling is a human sense, expressing strong sexual dimorphisms. We aim to improve the knowledge of the genetics of human olfactory perception by performing an …”
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Peripheral whole blood microRNA expression in relation to vascular function: a population-based study von Talevi, Valentina, Melas, Konstantinos, Pehlivan, Gökhan, Imtiaz, Mohammed A., Krüger, Dennis Manfred, Centeno, Tonatiuh Pena, Aziz, N. Ahmad, Fischer, Andre, Breteler, Monique M.B.

“… Background As key regulators of gene expression, microRNAs affect many cardiovascular mechanisms and have been associated with several cardiovascular diseases …”
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The Molecular Basis of Spinocerebellar Ataxia Type 7 von Goswami, Rituparna, Bello, Abudu I., Bean, Joe, Costanzo, Kara M., Omer, Bwaar, Cornelio-Parra, Dayanne, Odah, Revan, Ahluwalia, Amit, Allan, Shefaa K., Nguyen, Nghi, Shores, Taylor, Aziz, N. Ahmad, Mohan, Ryan D.

“… Spinocerebellar ataxia (SCA) type 7 (SCA7) is caused by a CAG trinucleotide repeat expansion in the ataxin 7 ( ATXN7 ) gene, which results in polyglutamine …”
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Associations of genetic liability for Alzheimer’s disease with cognition and eye movements in a large, population-based cohort study von Coors, Annabell, Imtiaz, Mohammed-Aslam, Boenniger, Meta M., Aziz, N. Ahmad, Ettinger, Ulrich, Breteler, Monique M. B.

“… To identify cognitive measures that may be particularly sensitive to early cognitive decline in preclinical Alzheimer’s disease (AD), we investigated the …”
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Increased hypothalamic-pituitary-adrenal axis activity in Huntington's disease von Aziz, N Ahmad, Pijl, Hanno, Frölich, Marijke, van der Graaf, A W Maurits, Roelfsema, Ferdinand, Roos, Raymund A C

“… Huntington's disease (HD) is a fatal hereditary neurodegenerative disorder characterized by motor, cognitive, and behavioral disturbances …”
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Isolated slow orthostatic tremor of the trunk von Aziz, N. Ahmad, Grobe-Einsler, Marcus, Kaut, Oliver

“… Slow orthostatic tremor is an extremely rare movement disorder with relatively low-frequency tremor (< 13 Hz) in the legs and trunk, which is evoked by …”
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Repeat length variations in polyglutamine disease-associated genes affect body mass index von Gardiner, Sarah L, de Mutsert, Renée, Trompet, Stella, Boogaard, Merel W, van Dijk, Ko Willems, Jukema, P J Wouter, Slagboom, P Eline, Roos, Raymund A C, Pijl, Hanno, Rosendaal, Frits R, Aziz, N Ahmad

“… The worldwide prevalence of obesity, a major risk factor for numerous debilitating chronic disorders, is increasing rapidly. Although a substantial amount of …”
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