Suchergebnisse - "Ayidah, Matilda"
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Molecular dependencies and genomic consequences of a global DNA damage tolerance defect
ISSN: 1474-760X, 1474-7596, 1474-760XVeröffentlicht: London BioMed Central 31.12.2024Veröffentlicht in Genome Biology (31.12.2024)“… Background DNA damage tolerance (DDT) enables replication to continue in the presence of fork stalling lesions. In mammalian cells, DDT is regulated by two …”
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Huwe1 supports B-cell development, B-cell-dependent immunity, somatic hypermutation and class switch recombination by regulating proliferation
ISSN: 1664-3224, 1664-3224Veröffentlicht: Switzerland Frontiers Media S.A 09.01.2023Veröffentlicht in Frontiers in immunology (09.01.2023)“… The development and differentiation of B cells is intimately linked to cell proliferation and the generation of diverse immunoglobulin gene ( Ig ) repertoires …”
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Mammalian life depends on two distinct pathways of DNA damage tolerance
ISSN: 1091-6490, 1091-6490Veröffentlicht: United States 24.01.2023Veröffentlicht in Proceedings of the National Academy of Sciences - PNAS (24.01.2023)“… DNA damage threatens genomic integrity and instigates stem cell failure. To bypass genotoxic lesions during replication, cells employ DNA damage tolerance …”
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Molecular dependencies and genomic consequences of a global DNA damage tolerance defect
ISSN: 2692-8205, 2692-8205Veröffentlicht: Cold Spring Harbor Cold Spring Harbor Laboratory Press 06.11.2023Veröffentlicht in bioRxiv (06.11.2023)“… DNA damage tolerance (DDT) enables replication to continue in the presence of fork stalling lesions. To determine the molecular and genomic impact of a global …”
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