Suchergebnisse - "Ayala Ceja, Melanie"

Self-regulating CAR-T cells modulate cytokine release syndrome in adoptive T-cell therapy von Lin, Meng-Yin, Nam, Eunwoo, Shih, Ryan M, Shafer, Amanda, Bouren, Amber, Ayala Ceja, Melanie, Harris, Caitlin, Khericha, Mobina, Vo, Kenny H, Kim, Minsoo, Tseng, Chi-Hong, Chen, Yvonne Y

“… Cytokine release syndrome (CRS) is a frequently observed side effect of chimeric antigen receptor (CAR)-T cell therapy. Here, we report self-regulating T cells …”
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CAR-T cell manufacturing: Major process parameters and next-generation strategies von Ayala Ceja, Melanie, Khericha, Mobina, Harris, Caitlin M, Puig-Saus, Cristina, Chen, Yvonne Y

“… Chimeric antigen receptor (CAR)-T cell therapies have demonstrated strong curative potential and become a critical component in the array of B-cell malignancy …”
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CD19/CD20 Bispecific Chimeric Antigen Receptor (CAR) in Naive/Memory T Cells for the Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma von Larson, Sarah M, Walthers, Christopher M, Ji, Brenda, Ghafouri, Sanaz N, Naparstek, Jacob, Trent, Jacqueline, Chen, Jia Ming, Roshandell, Mobina, Harris, Caitlin, Khericha, Mobina, Schweppe, Thomas, Berent-Maoz, Beata, Gosliner, Stanley B, Almaktari, Amr, Ceja, Melanie Ayala, Allen-Auerbach, Martin S, Said, Jonathan, Nawaly, Karla, Mead, Monica, de Vos, Sven, Young, Patricia A, Oliai, Caspian, Schiller, Gary J, Timmerman, John M, Ribas, Antoni, Chen, Yvonne Y

“… To address antigen escape and loss of T-cell functionality, we report a phase I clinical trial (NCT04007029) evaluating autologous naive and memory T (TN/MEM) …”
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