Suchergebnisse - "Aspelund, Thor"

A genome-wide association study of serum proteins reveals shared loci with common diseases von Gudjonsson, Alexander, Gudmundsdottir, Valborg, Axelsson, Gisli T., Gudmundsson, Elias F., Jonsson, Brynjolfur G., Launer, Lenore J., Lamb, John R., Jennings, Lori L., Aspelund, Thor, Emilsson, Valur, Gudnason, Vilmundur

“… With the growing number of genetic association studies, the genotype-phenotype atlas has become increasingly more complex, yet the functional consequences of …”
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Co-regulatory networks of human serum proteins link genetics to disease von Emilsson, Valur, Ilkov, Marjan, Lamb, John R, Finkel, Nancy, Gudmundsson, Elias F, Pitts, Rebecca, Hoover, Heather, Gudmundsdottir, Valborg, Horman, Shane R, Aspelund, Thor, Shu, Le, Trifonov, Vladimir, Sigurdsson, Sigurdur, Manolescu, Andrei, Zhu, Jun, Olafsson, Örn, Jakobsdottir, Johanna, Lesley, Scott A, To, Jeremy, Zhang, Jia, Harris, Tamara B, Launer, Lenore J, Zhang, Bin, Eiriksdottir, Gudny, Yang, Xia, Orth, Anthony P, Jennings, Lori L, Gudnason, Vilmundur

“… Proteins circulating in the blood are critical for age-related disease processes; however, the serum proteome has remained largely unexplored. To this end, …”
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Coding and regulatory variants are associated with serum protein levels and disease von Emilsson, Valur, Gudmundsdottir, Valborg, Gudjonsson, Alexander, Jonmundsson, Thorarinn, Jonsson, Brynjolfur G., Karim, Mohd A., Ilkov, Marjan, Staley, James R., Gudmundsson, Elias F., Launer, Lenore J., Lindeman, Jan H., Morton, Nicholas M., Aspelund, Thor, Lamb, John R., Jennings, Lori L., Gudnason, Vilmundur

“… Circulating proteins can be used to diagnose and predict disease-related outcomes. A deep serum proteome survey recently revealed close associations between …”
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Arterial stiffness, pressure and flow pulsatility and brain structure and function: the Age, Gene/Environment Susceptibility--Reykjavik study von Mitchell, Gary F, van Buchem, Mark A, Sigurdsson, Sigurdur, Gotal, John D, Jonsdottir, Maria K, Kjartansson, Ólafur, Garcia, Melissa, Aspelund, Thor, Harris, Tamara B, Gudnason, Vilmundur, Launer, Lenore J

“… Aortic stiffness increases with age and vascular risk factor exposure and is associated with increased risk for structural and functional abnormalities in the …”
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Increased respiratory morbidity associated with exposure to a mature volcanic plume from a large Icelandic fissure eruption von Carlsen, Hanne Krage, Ilyinskaya, Evgenia, Baxter, Peter J., Schmidt, Anja, Thorsteinsson, Throstur, Pfeffer, Melissa Anne, Barsotti, Sara, Dominici, Francesca, Finnbjornsdottir, Ragnhildur Gudrun, Jóhannsson, Thorsteinn, Aspelund, Thor, Gislason, Thorarinn, Valdimarsdóttir, Unnur, Briem, Haraldur, Gudnason, Thorolfur

“… The 2014–15 Holuhraun eruption in Iceland was the largest fissure eruption in over 200 years, emitting prodigious amounts of gas and particulate matter into …”
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Adverse childhood experiences and resilience among adult women: A population-based study von Daníelsdóttir, Hilda Björk, Aspelund, Thor, Thordardottir, Edda Bjork, Fall, Katja, Fang, Fang, Tómasson, Gunnar, Rúnarsdóttir, Harpa, Yang, Qian, Choi, Karmel W, Kennedy, Beatrice, Halldorsdottir, Thorhildur, Lu, Donghao, Song, Huan, Jakobsdóttir, Jóhanna, Hauksdóttir, Arna, Valdimarsdóttir, Unnur Anna

“… Adverse childhood experiences (ACEs) have consistently been associated with elevated risk of multiple adverse health outcomes, yet their contribution to coping …”
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Improved brain perfusion after electrical cardioversion of atrial fibrillation von Gardarsdottir, Marianna, Sigurdsson, Sigurdur, Aspelund, Thor, Gardarsdottir, Valdis Anna, Forsberg, Lars, Gudnason, Vilmundur, Arnar, David O

“… Abstract Aims Atrial fibrillation (AF) has been associated with reduced brain volume, cognitive impairment, and reduced cerebral blood flow. The causes of …”
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Prevalence and prognosis of ischaemic and non-ischaemic myocardial fibrosis in older adults von Shanbhag, Sujata M, Greve, Anders M, Aspelund, Thor, Schelbert, Erik B, Cao, J Jane, Danielsen, Ragnar, Þorgeirsson, Guðmundur, Sigurðsson, Sigurður, Eiríksdóttir, Guðný, Harris, Tamara B, Launer, Lenore J, Guðnason, Vilmundur, Arai, Andrew E

“… Non-ischaemic cardiomyopathies (NICM) can cause heart failure and death. Cardiac magnetic resonance (CMR) detects myocardial scar/fibrosis associated with …”
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Heterogeneity in White Blood Cells Has Potential to Confound DNA Methylation Measurements von Adalsteinsson, Bjorn T., Gudnason, Haukur, Aspelund, Thor, Harris, Tamara B., Launer, Lenore J., Eiriksdottir, Gudny, Smith, Albert V., Gudnason, Vilmundur

“… Epigenetic studies are commonly conducted on DNA from tissue samples. However, tissues are ensembles of cells that may each have their own epigenetic profile, …”
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Preeclampsia and academic performance in children: A nationwide study from Iceland von Sverrisson, Fridgeir A., Bateman, Brian T., Aspelund, Thor, Skulason, Sigurgrimur, Zoega, Helga

“… Hypertensive disorders complicate up to 10% of pregnancies. Evidence suggests a potential association between maternal hypertensive disorders during pregnancy, …”
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Prevalence and prognosis of unrecognized myocardial infarction determined by cardiac magnetic resonance in older adults von Schelbert, Erik B, Cao, Jie J, Sigurdsson, Sigurdur, Aspelund, Thor, Kellman, Peter, Aletras, Anthony H, Dyke, Christopher K, Thorgeirsson, Gudmundur, Eiriksdottir, Gudny, Launer, Lenore J, Gudnason, Vilmundur, Harris, Tamara B, Arai, Andrew E

“… Unrecognized myocardial infarction (MI) is prognostically important. Electrocardiography (ECG) has limited sensitivity for detecting unrecognized MI (UMI) …”
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Definition of excessive daytime sleepiness in the general population: Feeling sleepy relates better to sleep‐related symptoms and quality of life than the Epworth Sleepiness Scale score. Results from an epidemiological study von Thorarinsdottir, Elin H., Bjornsdottir, Erla, Benediktsdottir, Bryndis, Janson, Christer, Gislason, Thorarinn, Aspelund, Thor, Kuna, Samuel T., Pack, Allan I., Arnardottir, Erna S.

“… Many different subjective tools are being used to measure excessive daytime sleepiness (EDS) but the most widely used is the Epworth Sleepiness Scale (ESS) …”
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The Proteomic Profile of Interstitial Lung Abnormalities von Axelsson, Gisli Thor, Gudmundsson, Gunnar, Pratte, Katherine A, Aspelund, Thor, Putman, Rachel K, Sanders, Jason L, Gudmundsson, Elias F, Hatabu, Hiroto, Gudmundsdottir, Valborg, Gudjonsson, Alexander, Hino, Takuya, Hida, Tomoyuki, Hobbs, Brian D, Cho, Michael H, Silverman, Edwin K, Bowler, Russell P, Launer, Lenore J, Jennings, Lori L, Hunninghake, Gary M, Emilsson, Valur, Gudnason, Vilmundur

“… Knowledge on biomarkers of interstitial lung disease is incomplete. Interstitial lung abnormalities (ILAs) are radiologic changes that may present in its early …”
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Fractures and survival in multiple myeloma: results from a population-based study von Thorsteinsdottir, Sigrun, Gislason, Gauti, Aspelund, Thor, Sverrisdottir, Ingigerdur, Landgren, Ola, Turesson, Ingemar, Björkholm, Magnus, Kristinsson, Sigurður Y.

“… Multiple myeloma causes lytic bone lesions and fractures. The impact of fractures on multiple myeloma (MM) survival is unclear. The aim of this study was to …”
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Prevalence and determinants of carotid plaque in the cross-sectional REFINE-Reykjavik study von Sturlaugsdottir, Ran, Aspelund, Thor, Bjornsdottir, Gudlaug, Sigurdsson, Sigurdur, Thorsson, Bolli, Eiriksdottir, Gudny, Gudnason, Vilmundur

“… ObjectiveCarotid plaque and intima-media thickness are non-invasive arterial markers that are used as surrogate end points for cardiovascular disease. The aim …”
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Trends in the incidence and prevalence of atrial fibrillation in Iceland and future projections von Stefansdottir, Hrafnhildur, Aspelund, Thor, Gudnason, Vilmundur, Arnar, David O.

“… Aims Data are scarce on the epidemiology of atrial fibrillation (AF) in Europe. The aim of this study was to examine recent trends in the incidence and …”
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Cardiovascular disease and subsequent risk of psychiatric disorders: a nationwide sibling-controlled study von Shen, Qing, Song, Huan, Aspelund, Thor, Yu, Jingru, Lu, Donghao, Jakobsdóttir, Jóhanna, Bergstedt, Jacob, Yi, Lu, Sullivan, Patrick, Sjölander, Arvid, Ye, Weimin, Fall, Katja, Fang, Fang, Valdimarsdóttir, Unnur

“… The association between cardiovascular disease (CVD) and selected psychiatric disorders has frequently been suggested while the potential role of familial …”
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Blood metabolite markers of preclinical Alzheimer's disease in two longitudinally followed cohorts of older individuals von Casanova, Ramon, Varma, Sudhir, Simpson, Brittany, Kim, Min, An, Yang, Saldana, Santiago, Riveros, Carlos, Moscato, Pablo, Griswold, Michael, Sonntag, Denise, Wahrheit, Judith, Klavins, Kristaps, Jonsson, Palmi V, Eiriksdottir, Gudny, Aspelund, Thor, Launer, Lenore J, Gudnason, Vilmundur, Legido Quigley, Cristina, Thambisetty, Madhav

“… Recently, quantitative metabolomics identified a panel of 10 plasma lipids that were highly predictive of conversion to Alzheimer's disease (AD) in cognitively …”
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Hemostatic Factors and Risk of Coronary Heart Disease in General Populations: New Prospective Study and Updated Meta-Analyses von Willeit, Peter, Thompson, Alexander, Aspelund, Thor, Rumley, Ann, Eiriksdottir, Gudny, Lowe, Gordon, Gudnason, Vilmundur, Di Angelantonio, Emanuele

“… Activation of blood coagulation and fibrinolysis may be associated with increased risk of coronary heart disease. We aimed to assess associations of …”
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Mediation analysis of aortic stiffness and renal microvascular function von Woodard, Todd, Sigurdsson, Sigurdur, Gotal, John D, Torjesen, Alyssa A, Inker, Lesley A, Aspelund, Thor, Eiriksdottir, Gudny, Gudnason, Vilmundur, Harris, Tamara B, Launer, Lenore J, Levey, Andrew S, Mitchell, Gary F

“… Aortic stiffening, assessed by carotid-femoral pulse wave velocity, is associated with CKD. Transmission of excessive flow pulsatility into the low-impedance …”
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