Search Results - "Angius, Andrea"

DNA hydroxymethylation controls cardiomyocyte gene expression in development and hypertrophy by Greco, Carolina M., Kunderfranco, Paolo, Rubino, Marcello, Larcher, Veronica, Carullo, Pierluigi, Anselmo, Achille, Kurz, Kerstin, Carell, Thomas, Angius, Andrea, Latronico, Michael V. G., Papait, Roberto, Condorelli, Gianluigi

“…Methylation at 5-cytosine (5-mC) is a fundamental epigenetic DNA modification associated recently with cardiac disease. In contrast, the role of…”
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Genetic variants regulating immune cell levels in health and disease by Orrù, Valeria, Steri, Maristella, Sole, Gabriella, Sidore, Carlo, Virdis, Francesca, Dei, Mariano, Lai, Sandra, Zoledziewska, Magdalena, Busonero, Fabio, Mulas, Antonella, Floris, Matteo, Mentzen, Wieslawa I, Urru, Silvana A M, Olla, Stefania, Marongiu, Michele, Piras, Maria G, Lobina, Monia, Maschio, Andrea, Pitzalis, Maristella, Urru, Maria F, Marcelli, Marco, Cusano, Roberto, Deidda, Francesca, Serra, Valentina, Oppo, Manuela, Pilu, Rosella, Reinier, Frederic, Berutti, Riccardo, Pireddu, Luca, Zara, Ilenia, Porcu, Eleonora, Kwong, Alan, Brennan, Christine, Tarrier, Brendan, Lyons, Robert, Kang, Hyun M, Uzzau, Sergio, Atzeni, Rossano, Valentini, Maria, Firinu, Davide, Leoni, Lidia, Rotta, Gianluca, Naitza, Silvia, Angius, Andrea, Congia, Mauro, Whalen, Michael B, Jones, Chris M, Schlessinger, David, Abecasis, Gonçalo R, Fiorillo, Edoardo, Sanna, Serena, Cucca, Francesco

“…The complex network of specialized cells and molecules in the immune system has evolved to defend against pathogens, but inadvertent immune system attacks on…”
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Assessing Mitochondrial DNA Variation and Copy Number in Lymphocytes of ~2,000 Sardinians Using Tailored Sequencing Analysis Tools by Ding, Jun, Sidore, Carlo, Butler, Thomas J., Wing, Mary Kate, Qian, Yong, Meirelles, Osorio, Busonero, Fabio, Tsoi, Lam C., Maschio, Andrea, Angius, Andrea, Kang, Hyun Min, Nagaraja, Ramaiah, Cucca, Francesco, Abecasis, Gonçalo R., Schlessinger, David

“…DNA sequencing identifies common and rare genetic variants for association studies, but studies typically focus on variants in nuclear DNA and ignore the…”
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Assessing the Predictive Power of the Hemoglobin/Red Cell Distribution Width Ratio in Cancer: A Systematic Review and Future Directions by Coradduzza, Donatella, Medici, Serenella, Chessa, Carla, Zinellu, Angelo, Madonia, Massimo, Angius, Andrea, Carru, Ciriaco, De Miglio, Maria Rosaria

“…Background and Objectives: The hemoglobin (Hb)/red cell distribution width (RDW) ratio has emerged as an accessible, repeatable, and inexpensive prognostic…”
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Loss of Mismatched HLA in Leukemia after Stem-Cell Transplantation by Vago, Luca, Perna, Serena Kimi, Zanussi, Monica, Mazzi, Benedetta, Barlassina, Cristina, Stanghellini, Maria Teresa Lupo, Perrelli, Nicola Flavio, Cosentino, Cristian, Torri, Federica, Angius, Andrea, Forno, Barbara, Casucci, Monica, Bernardi, Massimo, Peccatori, Jacopo, Corti, Consuelo, Bondanza, Attilio, Ferrari, Maurizio, Rossini, Silvano, Roncarolo, Maria Grazia, Bordignon, Claudio, Bonini, Chiara, Ciceri, Fabio, Fleischhauer, Katharina

“…Five patients with acute myelogenous leukemia received hematopoietic stem-cell transplants from a haploidentical donor. They also received T cells from the…”
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The Changing Landscape of Naive T Cell Receptor Repertoire With Human Aging by Egorov, Evgeny S., Kasatskaya, Sofya A., Zubov, Vasiliy N., Izraelson, Mark, Nakonechnaya, Tatiana O., Staroverov, Dmitriy B., Angius, Andrea, Cucca, Francesco, Mamedov, Ilgar Z., Rosati, Elisa, Franke, Andre, Shugay, Mikhail, Pogorelyy, Mikhail V., Chudakov, Dmitriy M., Britanova, Olga V.

“…Human aging is associated with a profound loss of thymus productivity, yet naïve T lymphocytes still maintain their numbers by division in the periphery for…”
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Biomarker dynamics affecting neoadjuvant therapy response and outcome of HER2-positive breast cancer subtype by Orrù, Sandra, Pascariello, Emanuele, Pes, Barbara, Rallo, Vincenzo, Barbara, Raffaele, Muntoni, Marta, Notari, Francesca, Fancello, Gianfranco, Mocci, Cristina, Muroni, Maria Rosaria, Cossu-Rocca, Paolo, Angius, Andrea, De Miglio, Maria Rosaria

“…HER2+ breast cancer (BC) is an aggressive subtype genetically and biologically heterogeneous. We evaluate the predictive and prognostic role of HER2…”
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A Novel Null Homozygous Mutation Confirms CACNA2D2 as a Gene Mutated in Epileptic Encephalopathy by Pippucci, Tommaso, Parmeggiani, Antonia, Palombo, Flavia, Maresca, Alessandra, Angius, Andrea, Crisponi, Laura, Cucca, Francesco, Liguori, Rocco, Valentino, Maria Lucia, Seri, Marco, Carelli, Valerio

“…Contribution to epileptic encephalopathy (EE) of mutations in CACNA2D2, encoding α2δ-2 subunit of Voltage Dependent Calcium Channels, is unclear. To date only…”
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Transcriptome organization of white blood cells through gene co-expression network analysis in a large RNA-seq dataset by Forabosco, Paola, Pala, Mauro, Crobu, Francesca, Diana, Maria Antonietta, Marongiu, Mara, Cusano, Roberto, Angius, Andrea, Steri, Maristella, Orrù, Valeria, Schlessinger, David, Fiorillo, Edoardo, Devoto, Marcella, Cucca, Francesco

“…Gene co-expression network analysis enables identification of biologically meaningful clusters of co-regulated genes (modules) in an unsupervised manner. We…”
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Landscape of transcriptome variations uncovering known and novel driver events in colorectal carcinoma by Pira, Giovanna, Uva, Paolo, Scanu, Antonio Mario, Rocca, Paolo Cossu, Murgia, Luciano, Uleri, Elena, Piu, Claudia, Porcu, Alberto, Carru, Ciriaco, Manca, Alessandra, Persico, Ivana, Muroni, Maria Rosaria, Sanges, Francesca, Serra, Caterina, Dolei, Antonia, Angius, Andrea, De Miglio, Maria Rosaria

“…We focused on an integrated view of genomic changes in Colorectal cancer (CRC) and distant normal colon tissue (NTC) to test the effectiveness of expression…”
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A large-scale screening identified in USH2A gene the P3272L founder pathogenic variant explaining familial Usher syndrome in Sardinia, Italy by Serra, Rita, Rallo, Vincenzo, Steri, Maristella, Olla, Stefania, Piras, Maria Grazia, Marongiu, Michele, Gorospe, Myriam, Schlessinger, David, Pinna, Antonio, Fiorillo, Edoardo, Cucca, Francesco, Angius, Andrea

“…Background Usher syndrome (USH) encompasses a group of disorders characterized by congenital sensorineural hearing loss (SNHL) and retinitis pigmentosa (RP)…”
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Population Genomic Analysis of Ancient and Modern Genomes Yields New Insights into the Genetic Ancestry of the Tyrolean Iceman and the Genetic Structure of Europe by Sikora, Martin, Carpenter, Meredith L., Moreno-Estrada, Andres, Henn, Brenna M., Underhill, Peter A., Sánchez-Quinto, Federico, Zara, Ilenia, Pitzalis, Maristella, Sidore, Carlo, Busonero, Fabio, Maschio, Andrea, Angius, Andrea, Jones, Chris, Mendoza-Revilla, Javier, Nekhrizov, Georgi, Dimitrova, Diana, Theodossiev, Nikola, Harkins, Timothy T., Keller, Andreas, Maixner, Frank, Zink, Albert, Abecasis, Goncalo, Sanna, Serena, Cucca, Francesco, Bustamante, Carlos D.

“…Genome sequencing of the 5,300-year-old mummy of the Tyrolean Iceman, found in 1991 on a glacier near the border of Italy and Austria, has yielded new insights…”
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Harnessing Minimal Residual Disease as a Predictor for Colorectal Cancer: Promising Horizons Amidst Challenges by Wen, Xiaofen, Coradduzza, Donatella, Shen, Jiaxin, Scanu, Antonio Mario, Muroni, Maria Rosaria, Massidda, Matteo, Rallo, Vincenzo, Carru, Ciriaco, Angius, Andrea, De Miglio, Maria Rosaria

“…Minimal Residual Disease (MRD) detection has emerged as an independent factor in clinical and pathological cancer assessment offering a highly effective method…”
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Environmental and Genetic Contribution to Hypertension Prevalence: Data from an Epidemiological Survey on Sardinian Genetic Isolates by Biino, Ginevra, Parati, Gianfranco, Concas, Maria Pina, Adamo, Mauro, Angius, Andrea, Vaccargiu, Simona, Pirastu, Mario

“…Hypertension represents a major cause of cardiovascular morbidity and mortality worldwide but its prevalence has been shown to vary in different countries. The…”
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A Portrait of Intratumoral Genomic and Transcriptomic Heterogeneity at Single-Cell Level in Colorectal Cancer by Angius, Andrea, Scanu, Antonio Mario, Arru, Caterina, Muroni, Maria Rosaria, Carru, Ciriaco, Porcu, Alberto, Cossu-Rocca, Paolo, De Miglio, Maria Rosaria

“…In the study of cancer, omics technologies are supporting the transition from traditional clinical approaches to precision medicine. Intra-tumoral…”
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Novel ANKRD11 gene mutation in an individual with a mild phenotype of KBG syndrome associated to a GEFS+ phenotypic spectrum: a case report by Alves, Rita Maria, Uva, Paolo, Veiga, Marielza F., Oppo, Manuela, Zschaber, Fabiana C. R., Porcu, Giampiero, Porto, Henrique P., Persico, Ivana, Onano, Stefano, Cuccuru, Gianmauro, Atzeni, Rossano, Vieira, Lauro C. N., Pires, Marcos V. A., Cucca, Francesco, Toralles, Maria Betânia P., Angius, Andrea, Crisponi, Laura

“…Background KBG syndrome is a very rare autosomal dominant disorder, characterized by macrodontia, distinctive craniofacial findings, skeletal findings,…”
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A novel founder MYO15A frameshift duplication is the major cause of genetic hearing loss in Oman by Palombo, Flavia, Al-Wardy, Nadia, Ruscone, Guido Alberto Gnecchi, Oppo, Manuela, Kindi, Mohammed Nasser Al, Angius, Andrea, Al Lamki, Khalsa, Girotto, Giorgia, Giangregorio, Tania, Benelli, Matteo, Magi, Alberto, Seri, Marco, Gasparini, Paolo, Cucca, Francesco, Sazzini, Marco, Al Khabori, Mazin, Pippucci, Tommaso, Romeo, Giovanni

“…The increased risk for autosomal recessive disorders is one of the most well-known medical implications of consanguinity. In the Sultanate of Oman, a country…”
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Correction: Assessing Mitochondrial DNA Variation and Copy Number in Lymphocytes of ~2,000 Sardinians Using Tailored Sequencing Analysis Tools by Ding, Jun, Sidore, Carlo, Butler, Thomas J., Wing, Mary Kate, Qian, Yong, Meirelles, Osorio, Busonero, Fabio, Tsoi, Lam C., Maschio, Andrea, Angius, Andrea, Kang, Hyun Min, Nagaraja, Ramaiah, Cucca, Francesco, Abecasis, Gonçalo R., Schlessinger, David

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High Differentiation among Eight Villages in a Secluded Area of Sardinia Revealed by Genome-Wide High Density SNPs Analysis by Pistis, Giorgio, Piras, Ignazio, Pirastu, Nicola, Persico, Ivana, Sassu, Alessandro, Picciau, Andrea, Prodi, Dionigio, Fraumene, Cristina, Mocci, Evelina, Manias, Maria Teresa, Atzeni, Rossano, Cosso, Massimiliano, Pirastu, Mario, Angius, Andrea

“…To better design association studies for complex traits in isolated populations it's important to understand how history and isolation moulded the genetic…”
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A novel founder MYO15A frameshift duplication is the major cause of genetic hearing loss in Oman by Palombo, Flavia, Al-Wardy, Nadia, Ruscone, Guido Alberto Gnecchi, Oppo, Manuela, Kindi, Mohammed Nasser Al, Angius, Andrea, Al Lamki, Khalsa, Girotto, Giorgia, Giangregorio, Tania, Benelli, Matteo, Magi, Alberto, Seri, Marco, Gasparini, Paolo, Cucca, Francesco, Sazzini, Marco, Al Khabori, Mazin, Pippucci, Tommaso, Romeo, Giovanni

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