Suchergebnisse - "Agache, Ioana"

Endotypes of allergic diseases and asthma: An important step in building blocks for the future of precision medicine von Agache, Ioana, Akdis, Cezmi A.

“… Discoveries from basic science research in the last decade have brought significant progress in knowledge of pathophysiologic processes of allergic diseases, …”
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Astegolimab (anti-ST2) efficacy and safety in adults with severe asthma: A randomized clinical trial von Kelsen, Steven G., Agache, Ioana O., Soong, Weily, Israel, Elliot, Chupp, Geoffrey L., Cheung, Dorothy S., Theess, Wiebke, Yang, Xiaoying, Staton, Tracy L., Choy, David F., Fong, Alice, Dash, Ajit, Dolton, Michael, Pappu, Rajita, Brightling, Christopher E.

“… The IL-33/ST2 pathway is linked with asthma susceptibility. Inhaled allergens, pollutants, and respiratory viruses, which trigger asthma exacerbations, induce …”
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Advances and highlights in asthma in 2021 von Agache, Ioana, Eguiluz‐Gracia, Ibon, Cojanu, Catalina, Laculiceanu, Alexandru, Giacco, Stefano, Zemelka‐Wiacek, Magdalena, Kosowska, Anna, Akdis, Cezmi A., Jutel, Marek

“… Last year brought a significant advance in asthma management, unyielding to the pressure of the pandemics. Novel key findings in asthma pathogenesis focus on …”
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The effect of allergy and asthma as a comorbidity on the susceptibility and outcomes of COVID-19 von Gao, Ya-Dong, Agache, Ioana, Akdis, Mübeccel, Nadeau, Kari, Klimek, Ludger, Jutel, Marek, Akdis, Cezmi A

“… The coronavirus disease 2019 (COVID-19) pandemic causes an overwhelming number of hospitalization and deaths with a significant socioeconomic impact. The vast …”
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Biomarkers for diagnosis and prediction of therapy responses in allergic diseases and asthma von Breiteneder, Heimo, Peng, Ya‐Qi, Agache, Ioana, Diamant, Zuzana, Eiwegger, Thomas, Fokkens, Wytske J., Traidl‐Hoffmann, Claudia, Nadeau, Kari, O'Hehir, Robyn E., O'Mahony, Liam, Pfaar, Oliver, Torres, Maria J., Wang, De‐Yun, Zhang, Luo, Akdis, Cezmi A.

“… Modern health care requires a proactive and individualized response to diseases, combining precision diagnosis and personalized treatment. Accordingly, the …”
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Increased serum IL-17 is an independent risk factor for severe asthma von Agache, Ioana, Ciobanu, Cristina, Agache, Costel, Anghel, Mariana

“… IL-17 expression was found to be associated with many inflammatory diseases in humans, such as rheumatoid arthritis, asthma, systemic lupus erythematosus and …”
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EAACI statement on the diagnosis, management and prevention of severe allergic reactions to COVID‐19 vaccines von Sokolowska, Milena, Eiwegger, Thomas, Ollert, Markus, Torres, Maria J., Barber, Domingo, Del Giacco, Stefano, Jutel, Marek, Nadeau, Kari C., Palomares, Oscar, Rabin, Ronald L., Riggioni, Carmen, Vieths, Stefan, Agache, Ioana, Shamji, Mohamed H.

“… The first approved COVID‐19 vaccines include Pfizer/BioNTech BNT162B2, Moderna mRNA‐1273 and AstraZeneca recombinant adenoviral ChAdOx1‐S. Soon after approval, …”
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EAACI Biologicals Guidelines—Recommendations for severe asthma von Agache, Ioana, Akdis, Cezmi A., Akdis, Mubeccel, Canonica, Giorgio Walter, Casale, Thomas, Chivato, Tomas, Corren, Jonathan, Chu, Derek K., Del Giacco, Stefano, Eiwegger, Thomas, Flood, Breda, Firinu, Davide, Gern, James E., Hamelmann, Eckard, Hanania, Nicola, Hernández‐Martín, Irene, Knibb, Rebeca, Mäkelä, Mika, Nair, Parameswaran, O’Mahony, Liam, Papadopoulos, Nikolaos G., Papi, Alberto, Park, Hae‐Sim, Pérez de Llano, Luis, Pfaar, Oliver, Quirce, Santiago, Sastre, Joaquin, Shamji, Mohamed, Schwarze, Jurgen, Palomares, Oscar, Jutel, Marek

“… Severe asthma imposes a significant burden on patients, families and healthcare systems. Management is difficult, due to disease heterogeneity, co‐morbidities, …”
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Immunotherapy: State-of-the-art review of therapies and theratypes von Agache, Ioana, Zemelka-Wiącek, Magdalena, Shamji, Mohamed H., Jutel, Marek

“… Through its disease-modifying potential, immunotherapy is the keystone to curing allergic diseases. Allergen immunotherapy, applied for more than a century, is …”
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Diagnosis and management of NSAID‐Exacerbated Respiratory Disease (N‐ERD)—a EAACI position paper von Kowalski, Marek L., Agache, Ioana, Bavbek, Sevim, Bakirtas, Arzu, Blanca, Miguel, Bochenek, Grażyna, Bonini, Matteo, Heffler, Enrico, Klimek, Ludger, Laidlaw, Tanya M., Mullol, Joaquim, Niżankowska‐Mogilnicka, Ewa, Park, Hae‐Sim, Sanak, Marek, Sanchez‐Borges, Mario, Sanchez‐Garcia, Silvia, Scadding, Glenis, Taniguchi, Masami, Torres, Maria J., White, Andrew A., Wardzyńska, Aleksandra

“… NSAID‐exacerbated respiratory disease (N‐ERD) is a chronic eosinophilic, inflammatory disorder of the respiratory tract occurring in patients with asthma …”
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Advances and recent developments in asthma in 2020 von Cevhertas, Lacin, Ogulur, Ismail, Maurer, Debbie J., Burla, Daniel, Ding, Mei, Jansen, Kirstin, Koch, Jana, Liu, Chengyao, Ma, Siyuan, Mitamura, Yasutaka, Peng, Yaqi, Radzikowska, Urszula, Rinaldi, Arturo O., Satitsuksanoa, Pattraporn, Globinska, Anna, Veen, Willem, Sokolowska, Milena, Baerenfaller, Katja, Gao, Ya‐dong, Agache, Ioana, Akdis, Mübeccel, Akdis, Cezmi A.

“… In this review, we discuss recent publications on asthma and review the studies that have reported on the different aspects of the prevalence, risk factors and …”
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From phenotypes to endotypes to asthma treatment von Agache, Ioana O

“… The current guidelines for asthma diagnosis and management do not recognize that different phenotypes of asthma exist, with significant variations in the …”
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EAACI Guidelines on Allergen Immunotherapy: House dust mite‐driven allergic asthma von Agache, Ioana, Lau, Susanne, Akdis, Cezmi A., Smolinska, Sylwia, Bonini, Matteo, Cavkaytar, Ozlem, Flood, Breda, Gajdanowicz, Pawe, Izuhara, Kenji, Kalayci, Omer, Mosges, Ralph, Palomares, Oscar, Papadopoulos, Nikolaos G., Sokolowska, Milena, Angier, Elisabeth, Fernandez‐Rivas, Montserrat, Pajno, Giovanni, Pfaar, Oliver, Roberts, Graham C., Ryan, Dermot, Sturm, Gunter J., Ree, Ronald, Varga, Eva M., Wijk, Roy Gerth, Yepes‐Nuñez, Juan José, Jutel, Marek

“… Allergen immunotherapy (AIT) has been in use for the treatment of allergic disease for more than 100 years. Asthma treatment relies mainly on corticosteroids …”
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Allergen immunotherapy for asthma prevention: A systematic review and meta‐analysis of randomized and non‐randomized controlled studies von Farraia, Mariana, Paciência, Inês, Castro Mendes, Francisca, Cavaleiro Rufo, João, Shamji, Mohamed, Agache, Ioana, Moreira, André

“… Background Allergen immunotherapy (AIT) is a disease‐modifying treatment for IgE‐mediated diseases. Randomized controlled trials (RCTs) support AIT's potential …”
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Asthma Biomarkers: Do They Bring Precision Medicine Closer to the Clinic? von Agache, Ioana, Rogozea, Liliana

“… Measurement of biomarkers has been incorporated within clinical research of asthma to characterize the population and to associate the disease with …”
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Role of dietary fiber in promoting immune health—An EAACI position paper von Venter, Carina, Meyer, Rosan W., Greenhawt, Matthew, Pali‐Schöll, Isabella, Nwaru, Bright, Roduit, Caroline, Untersmayr, Eva, Adel‐Patient, Karine, Agache, Ioana, Agostoni, Carlo, Akdis, Cezmi A., Feeney, Mary, Hoffmann‐Sommergruber, Karin, Lunjani, Nonhlanhla, Grimshaw, Kate, Reese, Imke, Smith, Peter K., Sokolowska, Milena, Vassilopoulou, Emilia, Vlieg‐Boerstra, Berber, Amara, Shriya, Walter, Jens, O'Mahony, Liam

“… Microbial metabolism of specific dietary components, such as fiber, contributes to the sophisticated inter‐kingdom dialogue in the gut that maintains a stable …”
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Hot topics in allergen immunotherapy, 2023: Current status and future perspective von Zemelka‐Wiacek, Magdalena, Agache, Ioana, Akdis, Cezmi A., Akdis, Mübeccel, Casale, Thomas B., Dramburg, Stephanie, Jahnz‐Różyk, Karina, Kosowska, Anna, Matricardi, Paolo M., Pfaar, Oliver, Shamji, Mohamed H., Jutel, Marek

“… The importance of allergen immunotherapy (AIT) is multifaceted, encompassing both clinical and quality‐of‐life improvements and cost‐effectiveness in the long …”
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Recent advances in the epithelial barrier theory von Pat, Yagiz, Yazici, Duygu, D’Avino, Paolo, Li, Manru, Ardicli, Sena, Ardicli, Ozge, Mitamura, Yasutaka, Akdis, Mübeccel, Dhir, Raja, Nadeau, Kari, Agache, Ioana, Ogulur, Ismail, Akdis, Cezmi A

“… The epithelial barrier theory links the recent rise in chronic non-communicable diseases, notably autoimmune and allergic disorders, to environmental agents …”
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Emerging concepts and challenges in implementing the exposome paradigm in allergic diseases and asthma: a Practall document von Agache, Ioana, Miller, Rachel, Gern, James E., Hellings, Peter W., Jutel, Marek, Muraro, Antonella, Phipatanakul, Wanda, Quirce, Santiago, Peden, David

“… Exposome research can improve the understanding of the mechanistic connections between exposures and health to help mitigate adverse health outcomes across the …”
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The Concept of One Health for Allergic Diseases and Asthma von Agache, Ioana, Laculiceanu, Alexandru, Spanu, Daniela, Grigorescu, Dan

“… The worldwide prevalence of allergic disease is rising as a result of complex gene-environment interactions that shape the immune system and host response …”
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