Výsledky vyhledávání - "692/4028/67/589/466"

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  1. 1

    Truncation and constitutive activation of the androgen receptor by diverse genomic rearrangements in prostate cancer Autor Henzler, Christine, Li, Yingming, Yang, Rendong, McBride, Terri, Ho, Yeung, Sprenger, Cynthia, Liu, Gang, Coleman, Ilsa, Lakely, Bryce, Li, Rui, Ma, Shihong, Landman, Sean R., Kumar, Vipin, Hwang, Tae Hyun, Raj, Ganesh V., Higano, Celestia S., Morrissey, Colm, Nelson, Peter S., Plymate, Stephen R., Dehm, Scott M.

    ISSN: 2041-1723, 2041-1723
    Vydáno: London Nature Publishing Group UK 29.11.2016
    Vydáno v Nature communications (29.11.2016)
    “…Molecularly targeted therapies for advanced prostate cancer include castration modalities that suppress ligand-dependent transcriptional activity of the…”
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  2. 2

    Androgen receptor binding sites enabling genetic prediction of mortality due to prostate cancer in cancer-free subjects Autor Ito, Shuji, Liu, Xiaoxi, Ishikawa, Yuki, Conti, David D., Otomo, Nao, Kote-Jarai, Zsofia, Suetsugu, Hiroyuki, Eeles, Rosalind A., Koike, Yoshinao, Hikino, Keiko, Yoshino, Soichiro, Tomizuka, Kohei, Horikoshi, Momoko, Ito, Kaoru, Uchio, Yuji, Momozawa, Yukihide, Kubo, Michiaki, Kamatani, Yoichiro, Matsuda, Koichi, Haiman, Christopher A., Ikegawa, Shiro, Nakagawa, Hidewaki, Terao, Chikashi

    ISSN: 2041-1723, 2041-1723
    Vydáno: London Nature Publishing Group UK 23.08.2023
    Vydáno v Nature communications (23.08.2023)
    “…), which has a critical role in PrCa. Taking advantage of large Japanese samples ever, a multi-ancestry meta-analysis comprising more than 300,000 subjects in total identifies 9 unreported loci including ZFHX3 , a tumor suppressor gene…”
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  3. 3

    Prostate cancer risk, screening and management in patients with germline BRCA1/2 mutations Autor Rajwa, Pawel, Quhal, Fahad, Pradere, Benjamin, Gandaglia, Giorgio, Ploussard, Guillaume, Leapman, Michael S, Gore, John L, Paradysz, Andrzej, Tilki, Derya, Merseburger, Axel S, Morgan, Todd M, Briganti, Alberto, Palapattu, Ganesh S, Shariat, Shahrokh F

    ISSN: 1759-4812, 1759-4820, 1759-4820
    Vydáno: England Nature Publishing Group 01.04.2023
    Vydáno v Nature reviews. Urology (01.04.2023)
    “…; however, optimal screening protocols for individuals with these mutations have been a subject of debate…”
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  4. 4

    A QSP model of prostate cancer immunotherapy to identify effective combination therapies Autor Coletti, Roberta, Leonardelli, Lorena, Parolo, Silvia, Marchetti, Luca

    ISSN: 2045-2322, 2045-2322
    Vydáno: London Nature Publishing Group UK 03.06.2020
    Vydáno v Scientific reports (03.06.2020)
    “…Immunotherapy, by enhancing the endogenous anti-tumor immune responses, is showing promising results for the treatment of numerous cancers refractory to…”
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  5. 5

    Thiol Groups as a Biomarker for the Diagnosis and Prognosis of Prostate Cancer Autor Koike, Alexsandro, Robles, Brunna Emanuella França, da Silva Bonacini, Ana Gabriela, de Alcantara, Camila Cataldi, Reiche, Edna Maria Vissoci, Dichi, Isaias, Maes, Michael, Cecchini, Rubens, Simão, Andréa Name Colado

    ISSN: 2045-2322, 2045-2322
    Vydáno: London Nature Publishing Group UK 04.06.2020
    Vydáno v Scientific reports (04.06.2020)
    “… This case-control study recruited 204 subjects, 73 patients with PCa, 67 patients with benign prostate hyperplasia (BPH…”
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  6. 6

    Intraprostatic locations of tumor foci of higher grade missed by diagnostic prostate biopsy among potential candidates for active surveillance Autor Kim, Kwangmo, Lee, Jung Keun, Choe, Gheeyoung, Hong, Sung Kyu

    ISSN: 2045-2322, 2045-2322
    Vydáno: London Nature Publishing Group UK 09.11.2016
    Vydáno v Scientific reports (09.11.2016)
    “… Among 444 subjects, patients with upgrading showed relatively higher prevalence of index tumor foci in anterior prostate than those without upgrading, though not reaching statistical significance (p = 0.252…”
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