Výsledky vyhledávání - "631/337/384/331"

Stability of Circulating Exosomal miRNAs in Healthy Subjects Autor Sanz-Rubio, David, Martin-Burriel, Inmaculada, Gil, Ana, Cubero, Pablo, Forner, Marta, Khalyfa, Abdelnaby, Marin, Jose M.

“… MiRNA levels were tested in 7 healthy subjects who underwent four different blood extractions…”
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Normalization strategies differently affect circulating miRNA profile associated with the training status Autor Faraldi, Martina, Gomarasca, Marta, Sansoni, Veronica, Perego, Silvia, Banfi, Giuseppe, Lombardi, Giovanni

“… profiles in sedentary and highly-trained subjects. As the physically active status is known to affect miRNA expression, they could be effective biomarkers of the homeostatic response…”
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MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins Autor Vickers, Kasey C., Palmisano, Brian T., Shoucri, Bassem M., Shamburek, Robert D., Remaley, Alan T.

“…–miRNA profile of normal subjects is significantly…”
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The widespread regulation of microRNA biogenesis, function and decay Autor Krol, Jacek, Loedige, Inga, Filipowicz, Witold

“… Recent research indicates that miRNA regulators themselves are subject to sophisticated control at the levels of miRNA metabolism and function…”
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Exosomal microRNA miR-92a concentration in serum reflects human brown fat activity Autor Chen, Yong, Buyel, Joschka J., Hanssen, Mark J. W., Siegel, Franziska, Pan, Ruping, Naumann, Jennifer, Schell, Michael, van der Lans, Anouk, Schlein, Christian, Froehlich, Holger, Heeren, Joerg, Virtanen, Kirsi A., van Marken Lichtenbelt, Wouter, Pfeifer, Alexander

“…) is still the standard for measuring BAT activity, but exposes subjects to ionizing radiation…”
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Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA Autor Zhang, Lin, Hou, Dongxia, Chen, Xi, Li, Donghai, Zhu, Lingyun, Zhang, Yujing, Li, Jing, Bian, Zhen, Liang, Xiangying, Cai, Xing, Yin, Yuan, Wang, Cheng, Zhang, Tianfu, Zhu, Dihan, Zhang, Dianmu, Xu, Jie, Chen, Qun, Ba, Yi, Liu, Jing, Wang, Qiang, Chen, Jianqun, Wang, Jin, Wang, Meng, Zhang, Qipeng, Zhang, Junfeng, Zen, Ke, Zhang, Chen-Yu

“… MIR168a is abundant in rice and is one of the most highly enriched exogenous plant miRNAs in the sera of Chinese subjects…”
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AGO-bound mature miRNAs are oligouridylated by TUTs and subsequently degraded by DIS3L2 Autor Yang, Acong, Shao, Tie-Juan, Bofill-De Ros, Xavier, Lian, Chuanjiang, Villanueva, Patricia, Dai, Lisheng, Gu, Shuo

“…’ ends are subject to frequent sequence modifications, which have been proposed to affect miRNA stability…”
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miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia Autor Jiang, Xi, Hu, Chao, Arnovitz, Stephen, Bugno, Jason, Yu, Miao, Zuo, Zhixiang, Chen, Ping, Huang, Hao, Ulrich, Bryan, Gurbuxani, Sandeep, Weng, Hengyou, Strong, Jennifer, Wang, Yungui, Li, Yuanyuan, Salat, Justin, Li, Shenglai, Elkahloun, Abdel G., Yang, Yang, Neilly, Mary Beth, Larson, Richard A., Le Beau, Michelle M., Herold, Tobias, Bohlander, Stefan K., Liu, Paul P., Zhang, Jiwang, Li, Zejuan, He, Chuan, Jin, Jie, Hong, Seungpyo, Chen, Jianjun

“…MicroRNAs are subject to precise regulation and have key roles in tumorigenesis. In contrast to the oncogenic role of miR-22 reported in myelodysplastic syndrome (MDS…”
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Decreased lipid metabolism but increased FA biosynthesis are coupled with changes in liver microRNAs in obese subjects with NAFLD Autor Latorre, J, Moreno-Navarrete, J M, Mercader, J M, Sabater, M, Rovira, Ò, Gironès, J, Ricart, W, Fernández-Real, J M, Ortega, F J

“…) call for additional validations. This study sought to investigate variations in genes and hepatic miRNAs in a sample of obese patients with or without NAFLD and human hepatocytes (HH). Subjects/Methods…”
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A Novel Serum 4-microRNA Signature for Lung Cancer Detection Autor Nadal, Ernest, Truini, Anna, Nakata, Asuka, Lin, Jules, Reddy, Rishindra M., Chang, Andrew C., Ramnath, Nithya, Gotoh, Noriko, Beer, David G., Chen, Guoan

“… in a discovery set of 70 serum samples obtained at lung tumor resection and 22 non-cancer subjects (NC…”
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Identification of miRNAs and their targets in wild tomato at moderately and acutely elevated temperatures by high-throughput sequencing and degradome analysis Autor Zhou, Rong, Wang, Qian, Jiang, Fangling, Cao, Xue, Sun, Mintao, Liu, Min, Wu, Zhen

“… High temperatures have been the subject of considerable attention due to their negative effects on plant growth and development…”
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Assessment of Circulating LncRNAs Under Physiologic and Pathologic Conditions in Humans Reveals Potential Limitations as Biomarkers Autor Schlosser, Kenny, Hanson, Jennifer, Villeneuve, Patrick J., Dimitroulakos, Jim, McIntyre, Lauralyn, Pilote, Louise, Stewart, Duncan J.

“…). Eighty-four lncRNAs, representing some of the most abundant and functionally relevant candidates identified in cellular studies, were assessed via RT-qPCR in plasma from PAH and healthy subjects…”
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Faecal miRNA profiles associated with age, sex, BMI, and lifestyle habits in healthy individuals Autor Francavilla, Antonio, Gagliardi, Amedeo, Piaggeschi, Giulia, Tarallo, Sonia, Cordero, Francesca, Pensa, Ruggero G., Impeduglia, Alessia, Caviglia, Gian Paolo, Ribaldone, Davide Giuseppe, Gallo, Gaetano, Grioni, Sara, Ferrero, Giulio, Pardini, Barbara, Naccarati, Alessio

“…) as derived by a self-reported questionnaire, using small RNA-sequencing data of samples from 335 healthy subjects…”
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microRNA-221 and microRNA-18a identification in stool as potential biomarkers for the non-invasive diagnosis of colorectal carcinoma Autor Yau, T O, Wu, C W, Dong, Y, Tang, C-M, Ng, S S M, Chan, F K L, Sung, J J Y, Yu, J

“…Background: The detection of microRNA (miRNA) dysregulation in stool is a novel approach for the diagnosis of colorectal carcinoma (CRC). The aim of this study…”
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Time-course responses of circulating microRNAs to three resistance training protocols in healthy young men Autor Cui, Shufang, Sun, Biao, Yin, Xin, Guo, Xia, Chao, Dingming, Zhang, Chunni, Zhang, Chen-Yu, Chen, Xi, Ma, Jizheng

“… The present study investigated the effects of three acute resistance training (RT) protocols on the time-course changes of the c-miRNAs profiles in young males. The subjects (n = 45…”
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Decreased HD-MIR2911 absorption in human subjects with the SIDT1 polymorphism fails to inhibit SARS-CoV-2 replication Autor Zhou, Zhen, Zhou, Yu, Jiang, Xia-Ming, Wang, Yanbo, Chen, Xi, Xiao, Gengfu, Zhang, Chen-Yu, Yi, Yongxiang, Zhang, Lei-Ke, Li, Liang

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MiR-135b-5p and MiR-499a-3p Promote Cell Proliferation and Migration in Atherosclerosis by Directly Targeting MEF2C Autor Xu, Zhiliang, Han, Yeming, Liu, Jiying, Jiang, Fan, Hu, Huili, Wang, Yan, Liu, Qiji, Gong, Yaoqin, Li, Xi

“… We compared the miRNA expressions in serum samples from 13 atherosclerotic CAD patients and 5 healthy control subjects and identified 36 differentially expressed miRNAs…”
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MicroRNA profiling of diagnostic needle aspirates from patients with pancreatic cancer Autor Ali, S, Saleh, H, Sethi, S, Sarkar, F H, Philip, P A

“… Subjects…”
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Gastric bypass surgery with exercise alters plasma microRNAs that predict improvements in cardiometabolic risk Autor Nunez Lopez, Y O, Coen, P M, Goodpaster, B H, Seyhan, A A

“… β-cell function in obese non-diabetic subjects. Exercise also improves S I and may be an effective adjunct therapy to RYGB surgery…”
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Adulthood blood levels of hsa-miR-29b-3p associate with preterm birth and adult metabolic and cognitive health Autor Marttila, Saara, Rovio, Suvi, Mishra, Pashupati P., Seppälä, Ilkka, Lyytikäinen, Leo-Pekka, Juonala, Markus, Waldenberger, Melanie, Oksala, Niku, Ala-Korpela, Mika, Harville, Emily, Hutri-Kähönen, Nina, Kähönen, Mika, Raitakari, Olli, Lehtimäki, Terho, Raitoharju, Emma

“…) and serum NMR metabolomics were performed for Young Finns Study subjects (aged 34–49 years, full-term n = 682, preterm n = 84). Preterm birth (vs. full-term…”
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