Suchergebnisse - "• Algorithms and Bioinformatics"

Gene Selection and Classification in High-Throughput Biological Data With Integrated Machine Learning Algorithms and Bioinformatics Approaches von Patil, Abhijeet R

“… With the rise of high throughput technologies in biomedical research, large volumes of expression profiling, methylation profiling, and RNA-sequencing data are …”
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Efficient Sequence Comparison Via Combining Alignment and Alignment-Free Techniques : Algorithms and Bioinformatics Research von Ayad, Lorraine Abdelmasih Khalil

“… Sequence comparison is the core computation of many applications involving textual representations of data. Edit distance is the most widely used measure to …”
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Statistical Algorithms and Bioinformatics Tools Development for Computational Analysis of High-throughput Transcriptomic Data von McDermaid, Adam

“… Next-Generation Sequencing technologies allow for a substantial increase in the amount of data available for various biological studies. In order to …”
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Optimizing background therapy in treatment-experienced HIV-1 patients by rules-based algorithms and bioinformatics von Svard, J, Sonnerborg, A

“… In HIV-1-infected patients with extensive drug resistance, the optimization of background antiretroviral therapy is essential when changing drugs after …”
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Prediction of NR3C1 as a methylation marker for the prevention and treatment of gastric cancer in Rhizoma Atractylodis Macrocephalae based on machine learning algorithm and bioinformatics analysis von Huang, Shicong, Gu, Qian, Chen, Yan, Huang, Xiaofang, Du, Yuhua, Zhou, Ziying, Nan, Yi, Yuan, Ling

“… The aim of this study was to identify the markers of Rhizoma Atractylodis Macrocephalae (RAM) for the prevention and treatment of gastric cancer using …”
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Molecular biomarkers for the prognosis of breast cancer: role of amino acid metabolism genes von Zhou, Yudong, Yu, Shibo, Zhu, Lizhe, Wang, Yalong, Duan, Chenglong, Li, Danni, Du, Jinsui, Zhang, Jiaqi, Zhang, Jianing, Ma, Ruichao, He, Jianjun, Ren, Yu, Wang, Bin

“… By employing advanced machine learning algorithms and bioinformatics analysis techniques, the impact of amino acid metabolism-related genes (AAMRGs …”
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Exosomal lncRNAs and cancer: connecting the missing links von Naderi-Meshkin, Hojjat, Lai, Xin, Amirkhah, Raheleh, Vera, Julio, Rasko, John E J, Schmitz, Ulf

“… Abstract Motivation Extracellular vesicles (EVs), including exosomes and microvesicles, are potent and clinically valuable tools for early diagnosis, prognosis …”
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Identification of metabolic biomarkers in idiopathic pulmonary arterial hypertension using targeted metabolomics and bioinformatics analysis von Yang, Chuang, Liu, Yi-Hang, Zheng, Hai-Kuo

“… This study used metabolomics, machine learning algorithms and bioinformatics to screen for potential metabolic biomarkers associated with the diagnosis of PAH …”
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Computational Structural Validation of CYP2C9 Mutations and Evaluation of Machine Learning Algorithms in Predicting the Therapeutic Outcomes of Warfarin von Sridharan, Kannan, Kumar, Thirumal, Manikandan, Suchetha, Prasanna, Gaurav, G, Lalitha, Al Banna, Rashed, Doss, George Priya

“… The study aimed to identify the key pharmacogenetic variable influencing the therapeutic outcomes of warfarin using machine learning algorithms and bioinformatics tools …”
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Modeling and experimental validation of covalent immobilization of Trametes maxima laccase on glyoxyl and MANA‐Sepharose CL 4B supports, for the use in bioconversion of residual colorants von Cutiño‐Avila, Bessy V., Sánchez‐López, María I., Cárdenas‐Moreno, Yosberto, González‐Durruthy, Michael, Ramos‐Leal, Miguel, Guerra‐Rivera, Gilda, González‐Bacerio, Jorge, Guisán, José M., Ruso, Juan M., Monte‐Martínez, Alberto

“… Our novel strategy for the rational design of immobilized derivatives (RDID) is directed to predict the behavior of the protein immobilized derivative before its synthesis, by the usage of mathematic algorithms and bioinformatics tools …”
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A comprehensive pan-cancer analysis of prognostic value and potential clinical implications of FTH1 in cancer immunotherapy von Luo, Yuejun, Liu, Chengming, Yao, Yuxin, Tang, Xiaoya, Yin, Enzhi, Lu, Zhiliang, Sun, Nan, He, Jie

“… The immune landscape and underlying mechanisms of FTH1 in the TIME were investigated by multiple algorithms and bioinformatics methods …”
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Recent advances in quantitative neuroproteomics von Craft, George E., Chen, Anshu, Nairn, Angus C.

“… improvements in mass spectrometric platforms, peptide identification algorithms and bioinformatic …”
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The hair follicle enigma von Bernard, Bruno A.

“… One can predict that computer science, algorithms and bioinformatics will assist in fostering our understanding hair biology …”
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Natural Plasmodium falciparum Infection Stimulates Human Antibodies to MSP1 Epitopes Identified in Mice Infection Models upon Non-Natural Modified Peptidomimetic Vaccination von Rodríguez, Zully Johana, Melo, Fredy Leonardo, Torres, Angela, Agrawal, Nikhil, Cortés-Vecino, Jesús Alfredo, Lozano, José Manuel

“… : Some predictive algorithms and bioinformatics tools resembling different biological environments, such as phagosome-lysosome proteolytic degradation, affinity, and the high frequency of malaria …”
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Integration of graph neural networks and transcriptomics analysis identify key pathways and gene signature for immunotherapy response and prognosis of skin melanoma von Ye, Maodong, Ren, Shuai, Luo, Huanjuan, Wu, Xiumin, Lian, Hongwei, Cai, Xiangna, Ji, Yingchang

“… Graph neural networks (GNNs), alongside other deep learning algorithms and bioinformatics approaches, have demonstrated substantial promise in advancing cancer diagnosis and treatment strategies …”
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Differential Expression of miR‐4520a Associated With Pyrin Mutations in Familial Mediterranean Fever (FMF) von Latsoudis, Helen, Mashreghi, Mir‐Farzin, Grün, Joachim R., Chang, Hyun‐Dong, Stuhlmüller, Bruno, Repa, Argyro, Gergiannaki, Irini, Kabouraki, Eleni, Vlachos, George S., Häupl, Thomas, Radbruch, Andreas, Sidiropoulos, Prodromos, Doukoumetzidis, Kimon, Kardassis, Dimitris, Niewold, Timothy B., Boumpas, Dimitrios T., Goulielmos, George N.

“… Implementation of in silico gene network prediction algorithms and bioinformatics analyses showed that miR …”
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Application of an angiogenesis-related genes risk model in lung adenocarcinoma prognosis and immunotherapy von Wang, Jinsong, Cui, Xue, Weng, Yiming, Wei, Jiayan, Chen, Xinyi, Wang, Peiwei, Wang, Tong, Qin, Jian, Peng, Min

“… Based on machine algorithms and bioinformatics, angiogenic gene-related risk scores (RS) were calculated. Patients in the high-risk category had a worse prognosis …”
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Identification of CD8 + T cell-related biomarkers and immune infiltration characteristic of rheumatoid arthritis von Wang, Qizun, Li, Qianqian, Wang, Ronghuan, Li, Yanning, Wang, Jie, Guo, Zhu, Li, Feng, Chen, Bohua, Xiang, Hongfei, Wang, Tianrui, Wu, Xiaolin

“… ) were chosen for KEGG and GO analysis. Besides, to explore biomarkers of RA in depth, machine learning algorithms and bioinformatics analysis were used, and we identified GDF15, IGLC1, and IGHM as diagnostic markers of RA …”
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Identification of T cell dysfunction molecular subtypes and exploration of potential immunotherapy targets in BRAF V600E-mutant colorectal cancer von Gu, Tiefeng, Qi, Haonan, Wang, Jiaqi, Sun, Liangwei, Su, Yongqi, Hu, Hanqing

“… Background Immunotherapy is an effective treatment for BRAF V600E-mutant colorectal cancer, but currently, only a few benefit from it. Therefore, exploring new …”
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Identification of neutrophil extracellular trap-related biomarkers in ulcerative colitis based on bioinformatics and machine learning von Li, Jiao, Liu, Yupei, Sun, Zhiyi, Zeng, Suqi, Zheng, Caisong

“… The incidence of ulcerative colitis (UC) is rapidly increasing worldwide, but existing therapeutics are limited. Neutrophil extracellular traps (NETs), which …”
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