Search Results - Transcription Factor Networks in Reprogramming
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Abstract 2938 Dissecting the Epigenetic and Transcriptional Dynamics of Somatic-to-iPS Reprogramming at Single-Cell Resolution
ISSN: 0021-9258Published: Elsevier Inc 01.05.2025Published in The Journal of biological chemistry (01.05.2025)Get full text
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The pluripotency transcription factor network at work in reprogramming
ISSN: 0959-437X, 1879-0380, 1879-0380Published: England Elsevier Ltd 01.10.2014Published in Current opinion in genetics & development (01.10.2014)“…-associated transcription factor network…”
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Single-cell sequencing revealed metabolic reprogramming and its transcription factor regulatory network in prostate cancer
ISSN: 1936-5233, 1936-5233Published: United States Elsevier Inc 01.06.2024Published in Translational oncology (01.06.2024)“…: Insights from Single-Cell Sequencing.•Unlocking Metabolic Variations and Transcription Factor Dynamics Across Distinct Prostate Cancer Subtypes via Single-Cell Sequencing…”
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Lessons from a transcription factor: Alx1 provides insights into gene regulatory networks, cellular reprogramming, and cell type evolution
ISSN: 1557-8933, 1557-8933Published: United States 2022Published in Current topics in developmental biology (2022)“… The homeodomain-containing transcription factor, Alx1, was originally shown to be a core component of the skeletogenic GRN of the sea urchin embryo…”
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Diverse reprogramming codes for neuronal identity
ISSN: 0028-0836, 1476-4687, 1476-4687Published: London Nature Publishing Group UK 01.05.2018Published in Nature (London) (01.05.2018)“… The relationship between reprogramming factors and the transcriptional networks that produce neuronal identity and diversity remains largely unknown…”
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Krüppel-like factor 1 is a core cardiomyogenic trigger in zebrafish
ISSN: 1095-9203, 1095-9203Published: United States 09.04.2021Published in Science (American Association for the Advancement of Science) (09.04.2021)“… Transient Klf1 activation is sufficient to expand mature myocardium in uninjured hearts. Klf1 directs epigenetic reprogramming of the cardiac transcription factor network, permitting coordinated cardiomyocyte dedifferentiation and proliferation…”
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Liver-fibrosis-activated transcriptional networks govern hepatocyte reprogramming and intra-hepatic communication
ISSN: 1932-7420, 1932-7420Published: United States 03.08.2021Published in Cell metabolism (03.08.2021)“… The hepatocyte reprogramming was under tight cooperative control of a network of fibrosis-activated transcription factors, as exemplified by the transcription factor Elf-3 (ELF3…”
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Cellular reprogramming by transcription factor engineering
ISSN: 0959-437X, 1879-0380, 1879-0380Published: England Elsevier Ltd 01.10.2014Published in Current opinion in genetics & development (01.10.2014)“… Recent researches have identified multiple transcription factors as permissible reprogramming factors to pluripotency and lineage switching…”
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In Vivo Cellular Reprogramming: The Next Generation
ISSN: 1097-4172, 1097-4172Published: United States 08.09.2016Published in Cell (08.09.2016)“… While a combinatorial code was initially found to reprogram somatic cells to pluripotency, a "second generation" of cellular reprogramming involves lineage-restricted transcription factors and micro…”
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A Gene Regulatory Network for Cellular Reprogramming in Plant Regeneration
ISSN: 0032-0781, 1471-9053, 1471-9053Published: Japan Oxford University Press 01.04.2018Published in Plant and cell physiology (01.04.2018)“…) associated with plant cellular reprogramming by using an enhanced yeast one-hybrid (eY1H) screen systematically to identify regulatory relationships between 252 transcription factors (TFs) and 48 promoters…”
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Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice
ISSN: 2041-1723, 2041-1723Published: London Nature Publishing Group UK 28.03.2018Published in Nature communications (28.03.2018)“…Temporal and spatial-specific regulation of pluripotency networks is largely dependent on the precise modifications of core transcription factors…”
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Network analysis of transcription factors for nuclear reprogramming into induced pluripotent stem cell using bioinformatics
ISSN: 2228-5806, 2228-5814Published: Iran Royan Institute of Iran 2014Published in Cell journal (Yakhteh) (2014)“… As there is a lack of data on intra- and inter-networking among these six different transcription factors, the objective of this study is to analyze the intra- and inter-networks between them using bioinformatic…”
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Transcriptional pause release is a rate-limiting step for somatic cell reprogramming
ISSN: 1875-9777, 1875-9777Published: United States 06.11.2014Published in Cell stem cell (06.11.2014)“…Reactivation of the pluripotency network during somatic cell reprogramming by exogenous transcription factors involves chromatin remodeling and the recruitment of RNA polymerase II (Pol II) to target loci…”
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NKX3-1 is required for induced pluripotent stem cell reprogramming and can replace OCT4 in mouse and human iPSC induction
ISSN: 1465-7392, 1476-4679, 1476-4679Published: London Nature Publishing Group UK 01.08.2018Published in Nature cell biology (01.08.2018)“… Reprogramming somatic cells to induced pluripotent stem cells (iPSCs) is now routinely accomplished by overexpression of the four Yamanaka factors…”
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Reprogramming and remodeling: transcriptional and epigenetic regulation of salicylic acid-mediated plant defense
ISSN: 1460-2431, 1460-2431Published: England 17.08.2020Published in Journal of experimental botany (17.08.2020)“… Plant transcription factors and their co-regulators are critical players in establishing a transcription regulatory network and boosting plant immunity…”
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A single factor elicits multilineage reprogramming of astrocytes in the adult mouse striatum
ISSN: 1091-6490, 1091-6490Published: United States 15.03.2022Published in Proceedings of the National Academy of Sciences - PNAS (15.03.2022)“… In this study, we performed a series of in vivo screens and reveal that a single factor can induce resident brain astrocytes to become induced neural progenitor cells (iNPCs…”
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Delineating chromatin accessibility re-patterning at single cell level during early stage of direct cardiac reprogramming
ISSN: 0022-2828, 1095-8584, 1095-8584Published: England Elsevier Ltd 01.01.2022Published in Journal of molecular and cellular cardiology (01.01.2022)“…) on early reprogramming iCMs given the known epigenetic changes as early as day 3. This approach unveiled networks of transcription factors (TFs…”
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Transcriptional reprogramming at the intersection of the heat shock response and proteostasis
ISSN: 1097-4164, 1097-4164Published: United States 04.01.2024Published in Molecular cell (04.01.2024)“… The dramatic rewiring of gene and enhancer networks is driven by key transcription factors, including heat shock factors (HSFs…”
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DeepNEU: cellular reprogramming comes of age – a machine learning platform with application to rare diseases research
ISSN: 1750-1172, 1750-1172Published: London BioMed Central 10.01.2019Published in Orphanet journal of rare diseases (10.01.2019)“… We have developed an unsupervised deep machine learning technology, called DeepNEU that is based on a fully-connected recurrent neural network…”
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Nac1 facilitates pluripotency gene activation for establishing somatic cell reprogramming
ISSN: 0006-291X, 1090-2104, 1090-2104Published: United States Elsevier Inc 15.10.2019Published in Biochemical and biophysical research communications (15.10.2019)“…Transcription factors play a central role in pluripotency transcription circuitry for establishing pluripotent reprogramming…”
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