Výsledky vyhledávání - Cellular Reprogramming Techniques - history

A decade of transcription factor-mediated reprogramming to pluripotency Autor Takahashi, Kazutoshi, Yamanaka, Shinya

“…) by transcription factor-mediated somatic cell reprogramming. Takahashi and Yamanaka portray the path towards this ground-breaking discovery and discuss how, since then…”
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10th anniversary of iPS cells: the challenges that lie ahead Autor Aoi, Takashi

“… For example, various technologies for generating iPS cells have been developed, and we have cultivated a better understanding of the mechanisms involved in reprogramming…”
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Reprogramming lineage identity through cell–cell fusion Autor Brown, Karen E, Fisher, Amanda G

“…•Cell–cell fusion is a tractable system for studying the earliest events in lineage reprogramming…”
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What's in a cardiomyocyte – And how do we make one through reprogramming? Autor Keepers, Benjamin, Liu, Jiandong, Qian, Li

“…Substantial progress is being made in the field cardiac reprogramming, and those in the field are hopeful that the technology will be formulated for therapeutic use…”
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Otto Warburg: The journey towards the seminal discovery of tumor cell bioenergetic reprogramming Autor Urbano, Ana M.

“…Metabolic reprogramming is now regarded as a hallmark of cancer. This phenomenon was first observed at the level of cellular energetics, in the form of very…”
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Nuclear reprogramming in eggs Autor Gurdon, John

“… We could then understand how egg-reprogramming factors work. We might be able to reprogram somatic cell nuclei much more efficiently, using the endogenous molecules…”
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Historical review of research on plant cell dedifferentiation Autor Sugiyama, Munetaka

“… Subsequently, plant tissue and cell culture techniques, in which exciting progress was achieved after discovery of the hormonal control of cell proliferation and organogenesis in vitro in the 1950s…”
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Long-term culture and cloning of primary human bronchial basal cells that maintain multipotent differentiation capacity and CFTR channel function Autor Peters-Hall, Jennifer R, Coquelin, Melissa L, Torres, Michael J, LaRanger, Ryan, Alabi, Busola R, Sho, Sei, Calva-Moreno, Jose F, Thomas, Philip J, Shay, Jerry W

“… Recently, conditional reprogramming of cells (CRC) with a Rho-associated protein kinase (ROCK) inhibitor and culture on an irradiated fibroblast feeder layer resulted…”
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The egg and the nucleus: a battle for supremacy Autor Gurdon, J B

“… on the reprogramming field…”
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Konrad Hochedlinger: the new kid of nuclear reprogramming Autor Hochedlinger, Konrad

“…Hochedlinger pushes cells' developmental rewind buttons to examine their epigenetic history…”
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Nuclear transfer and reprogramming in fish Autor Wang, Xue-Geng, Zhu, Zuo-Yan, Sun, Yong-Hua, Zhao, Jue

“… Due to its advantages, zebrafish has become a unique animal model to study the mystery of reprogramming in nuclear transfer…”
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The cloning of a frog Autor Gurdon, J B

“…It is relatively unusual for the Nobel Prize in Physiology or Medicine to be made, to a large extent, on the basis of a single author paper, published over 50…”
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Regenerative Cardiovascular Therapies: Stem Cells and Beyond Autor Wernly, Bernhard, Mirna, Moritz, Rezar, Richard, Prodinger, Christine, Jung, Christian, Podesser, Bruno K., Kiss, Attila, Hoppe, Uta C., Lichtenauer, Michael

“…Although reperfusion therapy has improved outcomes, acute myocardial infarction (AMI) is still associated with both significant mortality and morbidity. Once…”
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The mysteries of induced pluripotency: where will they lead? Autor Nagy, Andras, Nagy, Kristina

“… model for studying the molecular nature of cellular identity…”
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Single-Cell Analysis of Clonal and Transcriptional Dynamics During Direct Reprogramming Autor Biddy, Brent Alan

“… This facilitates the construction of multi-level lineage trees, providing insights into cellular reprogramming trajectories…”
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Generation of induced pluripotent stem cells as a potential source of hematopoietic stem cells for transplant in PNH patients Autor Phondeechareon, Tanapol, Wattanapanitch, Methichit, U-pratya, Yaowalak, Damkham, Chanapa, Klincumhom, Nuttha, Lorthongpanich, Chanchao, Kheolamai, Pakpoom, Laowtammathron, Chuti, Issaragrisil, Surapol

“…Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired hemolytic anemia caused by lack of CD55 and CD59 on blood cell membrane leading to increased…”
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NOBEL 2012 Physiology or medicine: Mature cells can be rejuvenated Autor Rossant, Janet, Mummery, Christine

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Neuronal differentiation strategies: insights from single-cell sequencing and machine learning Autor Konstantinides, Nikolaos, Desplan, Claude

“…Neuronal replacement therapies rely on the differentiation of specific cell types from embryonic or induced pluripotent stem cells, or on the direct reprogramming of differentiated adult cells via…”
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Modeling of Human Genetic Diseases Via Cellular, Reprogramming Autor Kang, Min-Yong, Suh, Ji-Hoon, Han, Yong-Mahn

“… In this review, we summarized the concept and history of cellular reprogramming or iPSC generation and highlight recent progresses for disease modeling using patient-specific iPSCs. KCI Citation Count: 0…”
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Obituary: Xiangzhong (Jerry) Yang (1959-2009) Autor Trounson, Alan

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