The Heterogeneity of Cancer Metabolism

Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabo...

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Bibliographic Details
Format: Electronic eBook
Language:English
Published: Cham : Springer International Publishing, 2018.
Edition:1st ed. 2018.
Series:Advances in Experimental Medicine and Biology, 1063
Subjects:
Cancer research.
Immunology.
ISBN:9783319777368
ISSN:0065-2598 ;
Online Access: Get full text
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Table of Contents:
  • Part 1: The metabolism of cancer cells
  • Chapter 1: Glucose Metabolism
  • Chapter 2: Glutamine Metabolism
  • Chapter 3: Amino Acid Metabolism
  • Chapter 4: Lipid Metabolism
  • Chapter 5: Epigenetics and oncometabolites
  • Part 2: Heterogeneity of Cancer Metabolism - Chapter 1: Specific oncogenetic mutations lead to specific metabolic phenotypes within the same tissue of origin
  • Chapter 2: Intratumoral heterogeneity of cancer cell metabolism
  • - Chapter 3: Differential metabolism in vitro and in vivo
  • Part 3: Carcinoma associated fibroblasts
  • Chapter 1: Characteristics of CAF's
  • Chapter 2: Reverse Warbug EFF
  • Chapter 3: Metabolic exchange between CAFs and cancer cells. .

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