D-type Cyclins and Cancer

This volume provides an integrated account of our current understanding of the functions of D-type cyclins during development and tumorigenesis, with special emphasis on the kinase-independent functions of these proteins. The volume will provide a thorough review of the latest discoveries on the new...

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Bibliographische Detailangaben
Format: Elektronisch E-Book
Sprache:Englisch
Veröffentlicht: Cham : Springer International Publishing, 2018.
Ausgabe:1st ed. 2018.
Schriftenreihe:Current Cancer Research,
Schlagworte:
Cancer research.
Cell cycle.
Molecular biology.
ISBN:9783319644516
ISSN:2199-2584
Online-Zugang: Volltext
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Inhaltsangabe:
  • The D-type Cyclins: A Historical Perspective
  • Mammalian Development and Cancer - A Brief History of Mice Lacking D-type Cyclins or Cdk4/6
  • D-type Cyclins and Gene Transcription
  • Splice Variants and Phosphorylated Isoforms of Cyclin D1 in Tumorigenesis
  • Cyclin D1, Metabolism, and the Autophagy-Senescence Balance
  • Shifting a Paradigm: Cyclin D Activates pRb by Mono-Phosphorylation.

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