Haploidentical Transplantation Concepts & Clinical Application /

In this book, world-renowned experts in the field express well-reasoned opinions on a range of issues and controversies relating to haploidentical transplantation with the aim of providing practicing hematologists with clinically relevant and readily applicable information. Among the areas covered a...

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Format: Elektronisch E-Book
Sprache:Englisch
Veröffentlicht: Cham : Springer International Publishing, 2018.
Ausgabe:1st ed. 2018.
Schriftenreihe:Advances and Controversies in Hematopoietic Transplantation and Cell Therapy,
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ISBN:9783319543109
ISSN:2569-1376
Online-Zugang: Volltext
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024 7 |a 10.1007/978-3-319-54310-9  |2 doi 
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040 |a Springer-Nature  |b eng  |c CVTISR  |e AACR2 
041 |a eng 
245 1 0 |a Haploidentical Transplantation  |h [electronic resource] :  |b Concepts & Clinical Application /  |c edited by Stefan O. Ciurea, Rupert Handgretinger. 
250 |a 1st ed. 2018. 
260 1 |a Cham :  |b Springer International Publishing,  |c 2018. 
300 |a XI, 337 p. 25 illus., 18 illus. in color.  |b online resource. 
490 1 |a Advances and Controversies in Hematopoietic Transplantation and Cell Therapy,  |x 2569-1376 
500 |a Medicine  
505 0 |a Historical perspective and current trends in haploidentical transplantion -- Part 1: Graft manipulation and methods to control T-cell alloreactivity. -Positive CD34+ cell selection -- Selective allo-depletion: αβ and CD19+ cell T cell depletion -- T cell addback in T- cell depleted haploidentical transplant -- Hematopoietic myeloid growth factor primed bone marrow and peripheral blood hematopoietic progenitor cells -- Photodepletion of allo-reactive T cells -- Post-transplant cyclophosphamide in haploidentical transplant -- Part 2: Ideal graft & donor -- Graft source: Marrow versus peripheral blood with PTCy- Does it matter? -- Anti-HLA antibodies: Assessment and mitigating strategies -- Selection of haploidentical donors: What is the art? -- Myeloablative versus non-myeloablative conditioning regimen- Does it matter and how best to select? -- Part 3: Disease-specific pediatric population -- Nonmalignant diseases in children.- en.-="" part="" 4:="" disease-specific="" adult="" population.-="" non-malignant="" adults.-="" acute="" myelogenous="" leukemia="" lymphomas-="" parameswaran="" hari.-="" chronic="" leukemias="" and="" myeloproliferative="" neoplasms.-="" immunologic="" reconstitution="" after="" haploidentical="" transplantation.-="" prevention="" treatment="" of="" relapse="" transplant.-="" unique="" complications="" limitations="" future="" prospects="" transplantation. 
516 |a text file PDF 
520 |a In this book, world-renowned experts in the field express well-reasoned opinions on a range of issues and controversies relating to haploidentical transplantation with the aim of providing practicing hematologists with clinically relevant and readily applicable information. Among the areas covered are graft manipulation and methods to control T-cell alloreactivity, the nature of the ideal graft and donor, haploidentical transplantation in pediatric and adult patients with malignant and nonmalignant diseases, immunologic reconstitution following transplantation, complications, and the prevention and treatment of relapse post transplantation. Attention is drawn to the implications of high-impact clinical trials whenever such trials are available. The readily intelligible text is complemented by numerous helpful tables, algorithms, and figures. The book will provide practical support for hematologists and transplant physicians as they attempt to provide optimal care in this exciting but increasingly complex medical specialty. 
650 0 |a Hematology. 
650 0 |a Oncology . 
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