Coordinating Organismal Physiology Through the Unfolded Protein Response

This volume reviews the current research focused on the functional importance of unfolded protein response (UPR) signaling in the context of health and disease. The chapters present cutting-edge work describing the diverse functions of UPR signaling critical for regulating cellular and organismal ph...

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Médium: Elektronický zdroj E-kniha
Jazyk:angličtina
Vydáno: Cham : Springer International Publishing, 2018.
Vydání:1st ed. 2018.
Edice:Current Topics in Microbiology and Immunology, 414
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ISBN:9783319785301
ISSN:0070-217X ;
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245 1 0 |a Coordinating Organismal Physiology Through the Unfolded Protein Response  |h [electronic resource] /  |c edited by R. Luke Wiseman, Cole M. Haynes. 
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490 1 |a Current Topics in Microbiology and Immunology,  |x 0070-217X ;  |v 414 
500 |a Biomedical and Life Sciences  
505 0 |a Adapting Secretory Proteostasis and Function Through the Unfolded Protein Response -- Cell Non-Autonomous UPRER Signaling -- The unfolded protein response in the immune cell development: Putting the caretaker in the driving seat -- Mitochondria associated membranes and ER stress -- Coordinating Organismal Metabolism during Protein Misfolding in the ER Through the Unfolded Protein Response -- ER stress and neurodegenerative disease: a cause or effect relationship?- Driving cancer tumorigenesis and metastasis through UPR signaling -- ER Protein Quality Control and the Unfolded Protein Response in the Heart. 
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520 |a This volume reviews the current research focused on the functional importance of unfolded protein response (UPR) signaling in the context of health and disease. The chapters present cutting-edge work describing the diverse functions of UPR signaling critical for regulating cellular and organismal physiology under physiologic and pathologic conditions. Written by internationally respected scientists, this volume is designed to provide a broad view of the diverse functional importance of UPR, and as such appeals to clinicians and academic researchers alike. 
650 0 |a Immunology. 
650 0 |a Human physiology. 
650 0 |a Neurosciences. 
650 0 |a Cancer research. 
650 0 |a Infectious diseases. 
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