Delta Opioid Receptor Pharmacology and Therapeutic Applications

This volume describes our current understanding of the biological role of the delta-opioid receptor (DOR) system, focusing on its unique mechanisms of receptor trafficking and signaling in disease states. Part 1 covers the endogenous ligands that regulate the DOR system as well as novel compounds an...

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Médium: Elektronický zdroj E-kniha
Jazyk:angličtina
Vydáno: Cham : Springer International Publishing, 2018.
Vydání:1st ed. 2018.
Edice:Handbook of Experimental Pharmacology, 247
Témata:
Pharmacology.
Neurosciences.
Human physiology.
ISBN:9783319951331
ISSN:0171-2004 ;
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Obsah:
  • Part 1. DOPR Ligands
  • 1. Delta Opioid Receptor (DOR) Ligands and Pharmacology: Development of Indolo- and Quinolinomorphinan Derivatives Based on the Message-Address Concept
  • 2. Multifunctional Opioid Ligands
  • 3. Contribution of Delta-Opioid Receptors to Pathophysiological Events Explored by Endogenous Enkephalins
  • Part 2. DOPR Signaling
  • 4. Ligand-Directed Signaling at the Delta Opioid Receptor
  • 5. Delta Opioid Receptor Expression and Function in Primary Afferent Somatosensory Neurons
  • 6. Evidence and Function Relevance of Native DOR-MOR Heteromers
  • Part 3. DOPR and Disease
  • 8. The Delta Opioid Receptor in Pain Control
  • 9. Delta Opioid Receptors and Modulation of Mood and Emotion
  • 10. Delta Opioid Pharmacology in Relation to Alcohol Behaviors
  • 11. Delta Opioid Receptors: Learning and Motivation
  • 12. Delta Opioid Pharmacology in Parkinson's Disease
  • 13. Delta Opioid Receptor and Peptide: A Dynamic Therapy for Stroke and Other Neurological Disorders
  • 14. Delta Opioid Receptors and Cardioprotection
  • 15. The Roles of Opioid Receptors in Cutaneous Wound Healing. .

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