Delta Opioid Receptor Pharmacology and Therapeutic Applications
This volume describes our current understanding of the biological role of the delta-opioid receptor (DOR) system, focusing on its unique mechanisms of receptor trafficking and signaling in disease states. Part 1 covers the endogenous ligands that regulate the DOR system as well as novel compounds an...
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| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | Englisch |
| Veröffentlicht: |
Cham :
Springer International Publishing,
2018.
|
| Ausgabe: | 1st ed. 2018. |
| Schriftenreihe: | Handbook of Experimental Pharmacology,
247 |
| Schlagworte: | |
| ISBN: | 9783319951331 |
| ISSN: | 0171-2004 ; |
| Online-Zugang: |
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| 020 | |a 9783319951331 | ||
| 024 | 7 | |a 10.1007/978-3-319-95133-1 |2 doi | |
| 035 | |a CVTIDW08291 | ||
| 040 | |a Springer-Nature |b eng |c CVTISR |e AACR2 | ||
| 041 | |a eng | ||
| 245 | 1 | 0 | |a Delta Opioid Receptor Pharmacology and Therapeutic Applications |h [electronic resource] / |c edited by Emily M. Jutkiewicz. |
| 250 | |a 1st ed. 2018. | ||
| 260 | 1 | |a Cham : |b Springer International Publishing, |c 2018. | |
| 300 | |a VIII, 345 p. |b online resource. | ||
| 490 | 1 | |a Handbook of Experimental Pharmacology, |x 0171-2004 ; |v 247 | |
| 500 | |a Biomedical and Life Sciences | ||
| 505 | 0 | |a Part 1. DOPR Ligands -- 1. Delta Opioid Receptor (DOR) Ligands and Pharmacology: Development of Indolo- and Quinolinomorphinan Derivatives Based on the Message-Address Concept -- 2. Multifunctional Opioid Ligands -- 3. Contribution of Delta-Opioid Receptors to Pathophysiological Events Explored by Endogenous Enkephalins -- Part 2. DOPR Signaling -- 4. Ligand-Directed Signaling at the Delta Opioid Receptor -- 5. Delta Opioid Receptor Expression and Function in Primary Afferent Somatosensory Neurons -- 6. Evidence and Function Relevance of Native DOR-MOR Heteromers -- Part 3. DOPR and Disease -- 8. The Delta Opioid Receptor in Pain Control -- 9. Delta Opioid Receptors and Modulation of Mood and Emotion -- 10. Delta Opioid Pharmacology in Relation to Alcohol Behaviors -- 11. Delta Opioid Receptors: Learning and Motivation -- 12. Delta Opioid Pharmacology in Parkinson's Disease -- 13. Delta Opioid Receptor and Peptide: A Dynamic Therapy for Stroke and Other Neurological Disorders -- 14. Delta Opioid Receptors and Cardioprotection -- 15. The Roles of Opioid Receptors in Cutaneous Wound Healing. . | |
| 516 | |a text file PDF | ||
| 520 | |a This volume describes our current understanding of the biological role of the delta-opioid receptor (DOR) system, focusing on its unique mechanisms of receptor trafficking and signaling in disease states. Part 1 covers the endogenous ligands that regulate the DOR system as well as novel compounds and therapies used to modulate the DOR system. Part 2 describes new insights into the localization and trafficking of the DOR and how ligand-directed signaling alters the fate of the receptor. Part 3 concentrates on the potential role of the DOR system in disease states, such as pain, mood, addiction, and Parkinson's disease. Throughout the book, the DOR system as a target for drug development will be discussed. | ||
| 650 | 0 | |a Pharmacology. | |
| 650 | 0 | |a Neurosciences. | |
| 650 | 0 | |a Human physiology. | |
| 856 | 4 | 0 | |u http://hanproxy.cvtisr.sk/han/cvti-ebook-springer-eisbn-978-3-319-95133-1 |y Vzdialený prístup pre registrovaných používateľov |
| 910 | |b ZE05571 | ||
| 919 | |a 978-3-319-95133-1 | ||
| 974 | |a andrea.lebedova |f Elektronické zdroje | ||
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