Delta Opioid Receptor Pharmacology and Therapeutic Applications

This volume describes our current understanding of the biological role of the delta-opioid receptor (DOR) system, focusing on its unique mechanisms of receptor trafficking and signaling in disease states. Part 1 covers the endogenous ligands that regulate the DOR system as well as novel compounds an...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Format: Elektronisch E-Book
Sprache:Englisch
Veröffentlicht: Cham : Springer International Publishing, 2018.
Ausgabe:1st ed. 2018.
Schriftenreihe:Handbook of Experimental Pharmacology, 247
Schlagworte:
ISBN:9783319951331
ISSN:0171-2004 ;
Online-Zugang: Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

MARC

LEADER 00000nam a22000005i 4500
003 SK-BrCVT
005 20220618115403.0
007 cr nn 008mamaa
008 180927s2018 gw | s |||| 0|eng d
020 |a 9783319951331 
024 7 |a 10.1007/978-3-319-95133-1  |2 doi 
035 |a CVTIDW08291 
040 |a Springer-Nature  |b eng  |c CVTISR  |e AACR2 
041 |a eng 
245 1 0 |a Delta Opioid Receptor Pharmacology and Therapeutic Applications  |h [electronic resource] /  |c edited by Emily M. Jutkiewicz. 
250 |a 1st ed. 2018. 
260 1 |a Cham :  |b Springer International Publishing,  |c 2018. 
300 |a VIII, 345 p.  |b online resource. 
490 1 |a Handbook of Experimental Pharmacology,  |x 0171-2004 ;  |v 247 
500 |a Biomedical and Life Sciences  
505 0 |a Part 1. DOPR Ligands -- 1. Delta Opioid Receptor (DOR) Ligands and Pharmacology: Development of Indolo- and Quinolinomorphinan Derivatives Based on the Message-Address Concept -- 2. Multifunctional Opioid Ligands -- 3. Contribution of Delta-Opioid Receptors to Pathophysiological Events Explored by Endogenous Enkephalins -- Part 2. DOPR Signaling -- 4. Ligand-Directed Signaling at the Delta Opioid Receptor -- 5. Delta Opioid Receptor Expression and Function in Primary Afferent Somatosensory Neurons -- 6. Evidence and Function Relevance of Native DOR-MOR Heteromers -- Part 3. DOPR and Disease -- 8. The Delta Opioid Receptor in Pain Control -- 9. Delta Opioid Receptors and Modulation of Mood and Emotion -- 10. Delta Opioid Pharmacology in Relation to Alcohol Behaviors -- 11. Delta Opioid Receptors: Learning and Motivation -- 12. Delta Opioid Pharmacology in Parkinson's Disease -- 13. Delta Opioid Receptor and Peptide: A Dynamic Therapy for Stroke and Other Neurological Disorders -- 14. Delta Opioid Receptors and Cardioprotection -- 15. The Roles of Opioid Receptors in Cutaneous Wound Healing. . 
516 |a text file PDF 
520 |a This volume describes our current understanding of the biological role of the delta-opioid receptor (DOR) system, focusing on its unique mechanisms of receptor trafficking and signaling in disease states. Part 1 covers the endogenous ligands that regulate the DOR system as well as novel compounds and therapies used to modulate the DOR system. Part 2 describes new insights into the localization and trafficking of the DOR and how ligand-directed signaling alters the fate of the receptor. Part 3 concentrates on the potential role of the DOR system in disease states, such as pain, mood, addiction, and Parkinson's disease. Throughout the book, the DOR system as a target for drug development will be discussed. 
650 0 |a Pharmacology. 
650 0 |a Neurosciences. 
650 0 |a Human physiology. 
856 4 0 |u http://hanproxy.cvtisr.sk/han/cvti-ebook-springer-eisbn-978-3-319-95133-1  |y Vzdialený prístup pre registrovaných používateľov 
910 |b ZE05571 
919 |a 978-3-319-95133-1 
974 |a andrea.lebedova  |f Elektronické zdroje 
992 |a SUD 
999 |c 273136  |d 273136