Delta Opioid Receptor Pharmacology and Therapeutic Applications
This volume describes our current understanding of the biological role of the delta-opioid receptor (DOR) system, focusing on its unique mechanisms of receptor trafficking and signaling in disease states. Part 1 covers the endogenous ligands that regulate the DOR system as well as novel compounds an...
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| Médium: | Elektronický zdroj E-kniha |
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| Jazyk: | angličtina |
| Vydáno: |
Cham :
Springer International Publishing,
2018.
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| Vydání: | 1st ed. 2018. |
| Edice: | Handbook of Experimental Pharmacology,
247 |
| Témata: | |
| ISBN: | 9783319951331 |
| ISSN: | 0171-2004 ; |
| On-line přístup: |
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| Shrnutí: | This volume describes our current understanding of the biological role of the delta-opioid receptor (DOR) system, focusing on its unique mechanisms of receptor trafficking and signaling in disease states. Part 1 covers the endogenous ligands that regulate the DOR system as well as novel compounds and therapies used to modulate the DOR system. Part 2 describes new insights into the localization and trafficking of the DOR and how ligand-directed signaling alters the fate of the receptor. Part 3 concentrates on the potential role of the DOR system in disease states, such as pain, mood, addiction, and Parkinson's disease. Throughout the book, the DOR system as a target for drug development will be discussed. |
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| Popis jednotky: | Biomedical and Life Sciences |
| Fyzický popis: | VIII, 345 p. online resource. |
| ISBN: | 9783319951331 |
| ISSN: | 0171-2004 ; |