Acute and Chronic Neural Stimulation via Mechano-Sensitive Ion Channels

This book describes the tools, developed by the author, for perturbing endogenous mechano-sensitive ion channels for magneto-mechanical neuro-modulation. He explores the ways in which these tools compare against existing ones such as electricity, chemicals, optogenetics, and techniques like thermos/...

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Bibliographische Detailangaben
1. Verfasser: Tay, Andy Kah Ping (VerfasserIn)
Format: Elektronisch E-Book
Sprache:Englisch
Veröffentlicht: Cham : Springer International Publishing, 2018.
Ausgabe:1st ed. 2018.
Schriftenreihe:Springer Theses, Recognizing Outstanding Ph.D. Research,
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ISBN:9783319690599
ISSN:2190-5053
Online-Zugang: Volltext
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Beschreibung
Zusammenfassung:This book describes the tools, developed by the author, for perturbing endogenous mechano-sensitive ion channels for magneto-mechanical neuro-modulation. He explores the ways in which these tools compare against existing ones such as electricity, chemicals, optogenetics, and techniques like thermos/magneto-genetics. The author also reports on two platforms-magnetic ratcheting and magnetic microfluidics for directed evolution and high throughput culture of magnetotactic bacteria-that produce high quality magnetic nanoparticles for biomedical applications like neural stimulations. This thesis was submitted to and approved by the University of California, Los Angeles. Introduces technology for non-invasive control of neural activities that offer deep tissue penetration and controllable dosage; Examines the effects of biomechanical forces on cellular functions; Explores how to improve the reproducibility and uptake of magnetic tools for non-invasive neural modulation.
Beschreibung:Engineering
Beschreibung:XVII, 119 p. 33 illus., 32 illus. in color. online resource.
ISBN:9783319690599
ISSN:2190-5053