Abdominal Neuroendocrine Tumors

This book aims to equip readers with a better understanding of neuroendocrine tumors of the abdomen and explains how to manage them optimally by making use of novel therapeutic options that represent major advances on previous treatments. The most recent advances in epidemiology, genetics, molecular...

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Bibliographic Details
Format: Electronic eBook
Language:English
Published: Milano : Springer Milan , 2018.
Edition:1st ed. 2018.
Series:Updates in Surgery,
Subjects:
Abdominal surgery.
Surgical oncology.
Endocrinology .
ISBN:9788847039551
ISSN:2280-9848
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Table of Contents:
  • Foreword
  • Preface
  • 1 Anatomophysiology of the neuroendocrine system: Embryology, Anatomy - Histology - Citology, Physiology
  • 2 Epidemiology: Risk factors
  • 3 Classification: WHO (grading), site
  • 4 Pathology: Anatomic pathology, Immunohistochemistry. - 5 Molecular biology: Molecular pathways, Oncogenes, Suppressor genes
  • 6 Clinical presentations: Non functioning NETs
  • 7 Clinical presentations: Hormone releasing NETs (Carcinoid syndrome, Insulinoma, Glucagonoma, VIPoma, Somatostatinoma, Others, GRFoma
  • 8 MEN 1, MEN 2am, MEN 2b, and Others (TSC, VHL, NF1)
  • 9 Diagnosis: (Serum biomarkers, Endoscopy, Imaging (US, CT Scan, MRI, Angiography, Scintigraphy, PET)
  • 10 Staging: TNM
  • 11 Surgical treatment: Gastric NETs, Duodenum NETs, Jejuno-ileal NETs, Colorectal NETs, Pancreatic NETs (Head, Body-tail), Adrenal NETs
  • 12 Non surgical treatments: Chemotherapy, Hormonal syndrome treatment, Targeted therapies, IFN
  • 13 Metastatic disease: Liver metastases (Surgery, RF ablation and cryoablation, Arterial chemoembolization)
  • 14 Systemic therapy (Somatostatina analogs, Alpha IFN, Cytotoxic chemotherapy, Peptide receptor radiotherapy, VEGF inhibitors, mTOR inhibitors
  • 15 Flow-charts.

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