Chemistry of Nucleic Acids /

Life in all its forms is based on nucleic acids which store and transfer genetic information. The book addresses the main aspects of synthesis, hydrolytic stability, solution equilibria of nucleosides and nucleotides as well as base modifications of nucleic acids. The author further describes their...

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Hlavní autor: Lönnberg, Harri (Autor)
Médium: E-kniha
Jazyk:angličtina
Vydáno: Berlin ; Boston : De Gruyter, [2020]
©2020
Edice:De Gruyter Textbook
Témata:
Medizinische Biochemie.
Nucleinsäuren.
Nucleinsäurestoffwechsel.
Pro-Pharmakon.
SCIENCE / Life Sciences / Biochemistry.
biochémia
nukleová kyselina
elektronické dokumenty
ISBN:9783110609295
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Obsah:
  • Frontmatter
  • Preface
  • Contents
  • 1 Nucleosides: structure, nomenclature and solution equilibria
  • 2 Nucleosides: synthesis, reactions and use in chemotherapy
  • 3 Nucleotides
  • 4 Oligonucleotides: synthesis
  • 5 Oligonucleotides: reactions of phosphodiester linkages
  • 6 Oligonucleotide conjugates
  • 7 Nucleic acids
  • 8 Catalytic nucleic acids
  • 9 Nucleic acids as drugs and drug targets 1: antisense, splice-switching, triplex-forming and immune-stimulatory oligonucleotides
  • 10 Nucleic acids as drugs and drug targets 2: RNA interference, 2',5'-oligoadenylates and riboswitches
  • 11 Nucleic acids as drugs and drug targets 3: target recognition and delivery
  • Abbreviations
  • Index

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