Chemistry of Nucleic Acids /
Life in all its forms is based on nucleic acids which store and transfer genetic information. The book addresses the main aspects of synthesis, hydrolytic stability, solution equilibria of nucleosides and nucleotides as well as base modifications of nucleic acids. The author further describes their...
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| Format: | E-Book |
| Sprache: | Englisch |
| Veröffentlicht: |
Berlin ; Boston :
De Gruyter,
[2020]
©2020 |
| Schriftenreihe: | De Gruyter Textbook
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| Schlagworte: | |
| ISBN: | 9783110609295 |
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| 024 | 7 | |a 10.1515/9783110609295 |2 doi | |
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| 040 | |a DeGruyter |b eng |c CVTI SR |e AACR 2 | ||
| 041 | 0 | |a eng | |
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| 080 | |a 577 |2 2011 | ||
| 080 | |a 547.963.3 |2 2011 | ||
| 100 | 1 | |a Lönnberg, Harri, |e author. |4 aut | |
| 245 | 1 | 0 | |a Chemistry of Nucleic Acids / |c Harri Lönnberg. |
| 260 | |a Berlin ; |a Boston : |b De Gruyter, |c [2020] | ||
| 260 | |c ©2020 | ||
| 300 | |a 1 online resource (XI, 353 s.) | ||
| 490 | 0 | |a De Gruyter Textbook | |
| 500 | |a Popis urobený na základe titulnej stránky e-zdroja v PDF (web vydavateľa). | ||
| 505 | 0 | 0 | |t Frontmatter -- |t Preface -- |t Contents -- |t 1 Nucleosides: structure, nomenclature and solution equilibria -- |t 2 Nucleosides: synthesis, reactions and use in chemotherapy -- |t 3 Nucleotides -- |t 4 Oligonucleotides: synthesis -- |t 5 Oligonucleotides: reactions of phosphodiester linkages -- |t 6 Oligonucleotide conjugates -- |t 7 Nucleic acids -- |t 8 Catalytic nucleic acids -- |t 9 Nucleic acids as drugs and drug targets 1: antisense, splice-switching, triplex-forming and immune-stimulatory oligonucleotides -- |t 10 Nucleic acids as drugs and drug targets 2: RNA interference, 2',5'-oligoadenylates and riboswitches -- |t 11 Nucleic acids as drugs and drug targets 3: target recognition and delivery -- |t Abbreviations -- |t Index |
| 516 | |a text file PDF | ||
| 520 | |a Life in all its forms is based on nucleic acids which store and transfer genetic information. The book addresses the main aspects of synthesis, hydrolytic stability, solution equilibria of nucleosides and nucleotides as well as base modifications of nucleic acids. The author further describes their structural analogues used as therapeutic drugs, such as antivirals and anticancer agents, and prodrug strategies of nucleotides. | ||
| 538 | |a Internet via World Wide Web | ||
| 650 | 4 | |a Medizinische Biochemie. | |
| 650 | 4 | |a Nucleinsäuren. | |
| 650 | 4 | |a Nucleinsäurestoffwechsel. | |
| 650 | 4 | |a Pro-Pharmakon. | |
| 650 | 7 | |a SCIENCE / Life Sciences / Biochemistry. | |
| 653 | |a biochémia | ||
| 653 | |a nukleová kyselina | ||
| 655 | 4 | |a elektronické dokumenty | |
| 856 | 4 | 0 | |u http://hanproxy.cvtisr.sk/han/cvti-book-de-gruyter-isbn-9783110609295 |y Vzdialený prístup pre registrovaných používateľov. |
| 910 | |b ZE13007 | ||
| 959 | |a 44 | ||
| 974 | |a andrea.lebedova |f Elektronické zdroje | ||
| 992 | |a SUD | ||
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