RNA Metabolism in Neurodegenerative Diseases

It has become evident over the last years that abnormalities in RNA processing play a fundamental part in the pathogenesis of neurodegenerative diseases. Cellular viability depends on proper regulation of RNA metabolism and subsequent protein synthesis, which requires the interplay of many processes...

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Bibliographic Details
Format: Electronic eBook
Language:English
Published: Cham : Springer International Publishing, 2018.
Edition:1st ed. 2018.
Series:Advances in Neurobiology, 20
Subjects:
ISBN:9783319896892
ISSN:2190-5215 ;
Online Access: Get full text
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Table of Contents:
  • RNA Metabolism in Neurodegenerative Diseases
  • Mechanism of Splicing Regulation of Spinal Muscular Atrophy Genes
  • RNA Editing Deficiency in Neurodegeneration
  • RNA Nucleocytoplasmic Transport Defects in Neurodegenerative Diseases
  • RNA Degradation in Neurodegenerative Disease
  • RNP Assembly Defects in Spinal Muscular Atrophy
  • Stress Granules and ALS: A Case of Causation or Correlation?
  • Deregulation of RNA Metabolism in Microsatellite Expansion Diseases
  • Mechanisms Associated with TDP-43 Neurotoxicity in ALS/FTLD
  • Senataxin, a Novel Helicase at the Interface of RNA Transcriptome Regulation and Neurobiology: From Normal Function to Pathological Roles in Motor Neuron Disease and Cerebellar Degeneration
  • Lost in Translation - Evidence for Protein Synthesis Deficits in ALS/FTD and Related Neurodegenerative Diseases.