Selenium

This book summarizes the fast-growing and current knowledge about selenium interaction with cancer, diabetes, neuro-degeneration, heart disease, muscle disorders, HIV and several more. A special focus will be placed on in-depth knowledge about gene expression, selenoprotein biosynthesis, seleno-meta...

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Médium: Elektronický zdroj E-kniha
Jazyk:angličtina
Vydáno: Cham : Springer International Publishing, 2018.
Vydání:1st ed. 2018.
Edice:Molecular and Integrative Toxicology,
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ISBN:9783319953908
ISSN:2168-4219
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020 |a 9783319953908 
024 7 |a 10.1007/978-3-319-95390-8  |2 doi 
035 |a CVTIDW13906 
040 |a Springer-Nature  |b eng  |c CVTISR  |e AACR2 
041 |a eng 
245 1 0 |a Selenium  |h [electronic resource] /  |c edited by Bernhard Michalke. 
250 |a 1st ed. 2018. 
260 1 |a Cham :  |b Springer International Publishing,  |c 2018. 
300 |a XV, 522 p. 57 illus., 28 illus. in color.  |b online resource. 
490 1 |a Molecular and Integrative Toxicology,  |x 2168-4219 
500 |a Biomedical and Life Sciences  
505 0 |a Part I - Overview: 1. Selenium in Human Health and Disease: an Overview -- Part II - Bioaccessibility and Dietary Aspects of Selenium: 2. Selenium in Soils and Crops -- 3. Dietary Aspects for Selenium and/or Selenium Compounds -- Part III - Genes, Proteins, Pathways, and Metabolism Related to Selenium: 4. Contribution of the Yeast Saccharomyces Cerevisiae Model to Understand the Mechanisms of Selenium Toxicity -- 5. Selenium Metabolism, Regulation And Sex Differences In Mammals -- Part IV - The Role of Selenium within Redox System, Inflammation, and Thyroid Interaction: 6. Oxidative Stress, Selenium Redox Systems Including GPX / TXNRD Families -- 7. Selenium and Inflammatory Mediators -- 8. Selenium and Thyroid Function -- Part V - The Role of Selenium in Neurodevelopment and Neurological Disorders: 9. Selenium and Neurodevelopment -- 10. Selenium and Autism Spectrum Disorder -- 11. Selenium in Ischemic Stroke -- 12. Selenium neurotoxicity and Amyotrophic Lateral Sclerosis: An Epidemiologic Perspective -- Part VI - The Role of Selenium in Cancer: 13. Therapeutic Potential of Selenium Compounds in the Treatment of Cancer -- 14. Selenocystine and Cancer -- 15. Selenium in Radiation Oncology -- Part VII - The Role of Selenium in Various Diseases and Health Issues: 16. Selenium and Cardiovascular Disease: Epidemiological Evidence of a Possible U-Shaped Relationship -- 17. Selenium and Diabetes -- 18. Uncovering the Importance of Selenium in Muscle Disease -- 19. Selenium in Immune Response and Intensive Care -- 20. Selenium and Toxicological Aspects: Cytotoxicity, Cellular Bioavailability and Biotransformation of Se-Species -- 21. Selenium Nanoparticles - Biomedical Application -- 22. Selenium Interactions with Other Trace Elements, with Nutrients (and Drugs) in Humans -- Part VIII - Selenium Analytics, Speciation and Biomonitoring: 23. Biomarkers of Selenium Status -- 24. Human Biomonitoring of Selenium Exposure -- 25. Bioanalytical Chemistry of Selenium. 
516 |a text file PDF 
520 |a This book summarizes the fast-growing and current knowledge about selenium interaction with cancer, diabetes, neuro-degeneration, heart disease, muscle disorders, HIV and several more. A special focus will be placed on in-depth knowledge about gene expression, selenoprotein biosynthesis, seleno-metabolism--as well as the molecular pathways, physiological roles, and the molecular action of selenium including interaction with other elements and vitamins or as Se-nanoparticles. The reader will receive the newest information regarding redox status and redox regulatory systems, specifically in relation to different glutathione peroxidases and thioredoxin-reductases as well as about cellular bioavailability and cytotoxicity, de-balanced immune response, inflammation or dietary aspects. 
650 0 |a Pharmacology. 
650 0 |a Medical biochemistry. 
650 0 |a Molecular biology. 
856 4 0 |u http://hanproxy.cvtisr.sk/han/cvti-ebook-springer-eisbn-978-3-319-95390-8  |y Vzdialený prístup pre registrovaných používateľov 
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919 |a 978-3-319-95390-8 
974 |a andrea.lebedova  |f Elektronické zdroje 
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