RNA Therapeutics

Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence...

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Bibliographische Detailangaben
Format: Elektronisch E-Book
Sprache:Englisch
Veröffentlicht: Cham : Springer International Publishing, 2018.
Ausgabe:1st ed. 2018.
Schriftenreihe:Topics in Medicinal Chemistry, 27
Schlagworte:
Medicinal chemistry.
Bioorganic chemistry.
Pharmaceutical technology.
ISBN:9783319680910
ISSN:1862-2461 ;
Online-Zugang: Volltext
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Inhaltsangabe:
  • Computational Tools for Design of Selective Small Molecules Targeting RNA: From Small Molecule Microarrays to Chemical Similarity Searching
  • A Modular Approach to the Discovery and Affinity Maturation of Sequence-Selective RNA-Binding Compounds
  • Structure-Based Discovery of Small Molecules Binding to RNA
  • Approaches for the Discovery of Small Molecule Ligands Targeting microRNAs
  • Viral RNA Targets and Their Small Molecule Ligands
  • Drugging Pre-mRNA Splicing
  • Targeting RNA G-Quadruplexes for Potential Therapeutic Applications
  • The Therapeutic Targeting of Long Noncoding RNA
  • Messenger RNA as a Novel Therapeutic Approach.

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